KEGG   ENZYME: 4.2.3.57Help
Entry
EC 4.2.3.57                 Enzyme                                 

Name
(-)-beta-caryophyllene synthase;
beta-caryophyllene synthase;
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (caryophyllene-forming)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(-)-beta-caryophyllene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (-)-beta-caryophyllene + diphosphate [RN:R08541]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(-)-beta-caryophyllene [CPD:C09629];
diphosphate [CPD:C00013]
Comment
Widely distributed in higher plants, cf. EC 4.2.3.89 (+)-beta-caryophyllene synthase.
History
EC 4.2.3.57 created 2011, modified 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K14184  
alpha-humulene/beta-caryophyllene synthase
K15808  
beta-caryophyllene synthase
Genes
ATH: 
AT5G23960(TPS21)
ALY: 
CRB: 
EUS: 
Taxonomy
Reference
1  [PMID:12409018]
  Authors
Cai Y, Jia JW, Crock J, Lin ZX, Chen XY, Croteau R.
  Title
A cDNA clone for beta-caryophyllene synthase from Artemisia annua.
  Journal
Phytochemistry. 61 (2002) 523-9.
  Sequence
[up:Q8SA63]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
110639-18-4

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