KEGG   ENZYME: 4.2.3.63Help
Entry
EC 4.2.3.63                 Enzyme                                 

Name
(+)-cubenene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-cubenene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (+)-cubenene + diphosphate [RN:R09615]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(+)-cubenene [CPD:C19741];
diphosphate [CPD:C00013]
Comment
Requires Mg2+.
History
EC 4.2.3.63 created 2011
Reference
1
  Authors
Nabeta, K., Kigure, K., Fujita, M., Nagoya, T., Ishikawa, T., Okuyama, H. and Takasawa, T.
  Title
Bioynthesis of (+)-cubenene and (+)-epicubenol by cell-free extracts of cultured cells of Heteroscyphus planus and cyclization of [2H]farnesyl diphosphates.
  Journal
J. Chem. Soc., Perkin Trans. 1 (1995) 1935-1939.
Reference
2
  Authors
Nabeta, K., Fujita, M., Komuro, K., Katayama, K., and Takasawa, T.
  Title
In vitro biosynthesis of cadinanes by cell-free extracts of cultured cells of Heteroscyphus planus.
  Journal
J. Chem. Soc., Perkin Trans. 1 (1997) 2065-2070.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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