KEGG   ENZYME: 4.3.1.1Help
Entry
EC 4.3.1.1                  Enzyme                                 
Name aspartate ammonia-lyase;
aspartase;
fumaric aminase;
L-aspartase;
L-aspartate ammonia-lyase
Class Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname L-aspartate ammonia-lyase (fumarate-forming)
Reaction(IUBMB) L-aspartate = fumarate + NH3 [RN:R00490]
Reaction(KEGG) R00490
Show
Substrate L-aspartate [CPD:C00049]
Product fumarate [CPD:C00122];
NH3 [CPD:C00014]
Pathway PATH: ec00250  Alanine, aspartate and glutamate metabolism
PATH: ec00910  Nitrogen metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K01744  aspartate ammonia-lyase
Genes ECO: b4139(aspA)
ECJ: JW4099(aspA)
ECD: ECDH10B_4332(aspA)
EBW: BWG_3852(aspA)
ECE: Z5744(aspA)
ECS: ECs5120(aspA)
ECF: ECH74115_5655(aspA)
ETW: ECSP_5239(aspA)
ECG: E2348C_4465(aspA)
ECC: c5222(aspA)
ECI: UTI89_C4736(aspA)
ECP: ECP_4383(aspA)
ECV: APECO1_2250(aspA)
ECW: EcE24377A_4694(aspA)
ECX: EcHS_A4380(aspA)
ECM: EcSMS35_1116 EcSMS35_4608(aspA)
ECY: ECSE_4438(aspA)
ECL: EcolC_3873(aspA)
ECK: EC55989_4694(aspA)
ECQ: ECED1_4927(aspA)
ECR: ECIAI1_4372(aspA)
ECT: ECIAI39_4604(aspA)
ECZ: ECS88_4725(aspA)
EUM: ECUMN_4674(aspA)
ELF: LF82_0173(aspA)
EBL: B21_03971(aspA)
EBD: ECBD_3892
EBR: ECB_04009(aspA)
EOH: ECO103_4934(aspA)
EOI: ECO111_5074(aspA)
EOJ: ECO26_5305(aspA)
EFE: EFER_4191(aspA)
STY: STY4685(aspA)
STT: t4377(aspA)
SPT: SPA4142(aspA)
SEK: SSPA3846(aspA)
SPQ: SPAB_05455(aspA)
SEI: SPC_4476(aspA)
SEC: SC4204(aspA)
SEH: SeHA_C4744(aspA)
SEE: SNSL254_A4687(aspA)
SEW: SeSA_A4596(aspA)
SEA: SeAg_B4604(aspA)
SED: SeD_A4722(aspA)
SEG: SG4168(aspA)
SET: SEN4096(aspA)
SES: SARI_03306(aspA)
STM: STM4326(aspA)
YPE: YPO0348(aspA)
YPK: y0606(aspA)
YPM: YP_0502(aspA)
YPA: YPA_3934(aspA)
YPN: YPN_3322(aspA)
YPG: YpAngola_A0725(aspA)
YPP: YPDSF_3625(aspA)
YPS: YPTB0402(aspA)
YPI: YpsIP31758_3678(aspA)
YPY: YPK_3825(aspA)
YPB: YPTS_0428(aspA)
YEN: YE0351(aspA)
SFL: SF4293(aspA)
SFX: S4560(aspA)
SFV: SFV_4295(aspA)
SSN: SSON_4322(aspA)
SBO: SBO_4317(aspA)
SBC: SbBS512_E4668(aspA)
SDY: SDY_4444(aspA)
ECA: ECA0426(aspA1) ECA0621(aspA)
PCT: PC1_0398 PC1_0506
PWA: Pecwa_0480 Pecwa_0725
ETA: ETA_29860(aspA)
PLU: plu4137(aspA)
PAY: PAU_03760(aspA)
WBR: WGLp395(aspA)
SGL: SG0303
ENT: Ent638_0326(aspA)
ESA: ESA_00151(aspA)
CTU: Ctu_37170(aspA)
KPN: KPN_04529(aspA)
KPE: KPK_5142(aspA)
KPU: KP1_0395(aspA)
CKO: CKO_03696(aspA)
SPE: Spro_0406(aspA)
PMR: PMI2546(aspA)
EIC: NT01EI_0377
ETR: ETAE_0311(aspA)
HDE: HDEF_2247(aspA)
DDA: Dd703_3407
DDC: Dd586_0533
DZE: Dd1591_3532
HIN: HI0534(aspA)
HIT: NTHI0660(aspA)
HIP: CGSHiEE_00320(aspA)
HIQ: CGSHiGG_05925(aspA)
HDU: HD0564(aspA)
HAP: HAPS_1109(aspA)
HSO: HS_0466(aspA)
HSM: HSM_0765(aspA)
PMU: PM1103(aspA)
MSU: MS1984(aspA)
APL: APL_1091(aspA)
APJ: APJL_1107(aspA)
APA: APP7_1149(aspA)
ASU: Asuc_0141(aspA)
AAP: NT05HA_1685
AAT: D11S_0597
VCH: VC2698(aspA)
VCO: VC0395_A2270(aspA)
VCM: VCM66_2618(aspA)
VCJ: VCD_001670
VVU: VV1_1249(aspA)
VVY: VV3118(aspA)
VPA: VP2863(aspA)
VHA: VIBHAR_00154(aspA)
VSP: VS_2921(aspA)
VEX: VEA_002214
VFI: VF_2353(aspA)
VFM: VFMJ11_2474(aspA)
VSA: VSAL_I2806(aspA)
PPR: PBPRA3391(aspA) PBPRB0046
PAE: PA5429(aspA)
PAU: PA14_71650(aspA)
PAP: PSPA7_6217(aspA)
PAG: PLES_58241(aspA)
PPU: PP_5338(aspA)
PPF: Pput_5247(aspA)
PPG: PputGB1_5387(aspA)
PPW: PputW619_0135(aspA)
PST: PSPTO_5499(aspA)
PSB: Psyr_5051(aspA)
PSP: PSPPH_5133(aspA)
PFL: PFL_6128(aspA)
PFO: Pfl01_5625(aspA)
PFS: PFLU6057(aspA)
PEN: PSEEN5482(aspA)
PMY: Pmen_0128(aspA)
PSA: PST_0197(aspA)
PCR: Pcryo_1417(aspA)
PRW: PsycPRwf_1545(aspA)
ACI: ACIAD1744(aspA)
ACB: A1S_1726(aspA)
ABY: ABAYE1921(aspA)
ABC: ACICU_01762(aspA)
ABN: AB57_1955(aspA)
ABB: ABBFA_001769(aspA)
SFR: Sfri_0682(aspA)
SAZ: Sama_0789
SBL: Sbal_3747(aspA)
SBM: Shew185_0618(aspA)
SBN: Sbal195_0645(aspA)
SBP: Sbal223_0640(aspA)
SSE: Ssed_1091(aspA)
SWD: Swoo_1178(aspA)
CPS: CPS_2052(aspA)
HCH: HCH_01841(aspA)
MMW: Mmwyl1_1905 Mmwyl1_2652
AHA: AHA_0856(aspA)
ASA: ASA_3435(aspA)
TAU: Tola_3006
DNO: DNO_0874(aspA)
BCI: BCI_0593(aspA)
NMA: NMA1459(aspA)
NME: NMB1029(aspA)
NMC: NMC1185(aspA)
NMN: NMCC_1166(aspA)
NMI: NMO_1099(aspA)
NGO: NGO0556(aspA)
NGK: NGK_1372(aspA)
CVI: CV_4112(aspA)
REU: Reut_A1791(aspA)
BVI: Bcep1808_4633(aspA)
BUR: Bcep18194_B1984(aspA)
BCN: Bcen_4302(aspA)
BCH: Bcen2424_4064(aspA)
BCM: Bcenmc03_3458(aspA)
BCJ: BCAM1190(aspA)
BAM: Bamb_3457(aspA)
BAC: BamMC406_3964(aspA)
BPH: Bphy_5639
PNU: Pnuc_1746
RFR: Rfer_3846(aspA)
DIA: Dtpsy_1365
VAP: Vapar_0827
CTT: CtCNB1_4639
HAR: HEAR0768(aspA)
AZO: azo0437
DAR: Daro_0481(aspA)
TBD: Tbd_2119(aspA)
APP: CAP2UW1_3016
HPY: HP0649(aspA)
HPJ: jhp0594(aspA)
HPA: HPAG1_0634(aspA)
HPS: HPSH_03615(aspA)
HPG: HPG27_611(aspA)
HPP: HPP12_0662(aspA)
HPB: HELPY_0722(aspA)
HHE: HH0722(aspA)
HAC: Hac_1065(aspA)
WSU: WS0662(aspA)
CJE: Cj0087(aspA)
CJR: CJE0082(aspA)
CJJ: CJJ81176_0122(aspA)
CJU: C8J_0079(aspA)
CJD: JJD26997_0094(aspA)
CFF: CFF8240_1643(aspA)
CCV: CCV52592_2124
CHA: CHAB381_1555
CCO: CCC13826_0391
CLA: Cla_0140(aspA)
ABU: Abu_1581(aspA)
SDL: Sdel_2008 Sdel_2009
GSU: GSU0479(aspA)
GME: Gmet_3082(aspA)
GUR: Gura_0940(aspA)
GBM: Gbem_2795
GEO: Geob_1755
GEM: GM21_1415
PCA: Pcar_1630(aspA)
PPD: Ppro_0550 Ppro_1493(aspA)
DVU: DVU1766 DVU1871(aspA)
DVL: Dvul_1293(aspA) Dvul_1389
DVM: DvMF_0565(aspA)
DDE: Dde_1663(aspA) Dde_3552
DMA: DMR_00400(aspA) DMR_02490
DSA: Desal_1336 Desal_3071
LIP: LI0913(aspA)
DBA: Dbac_3455
DRT: Dret_2167
BBA: Bd2857(aspA)
DPS: DP0352(aspA)
ADE: Adeh_1757(aspA) Adeh_2602
ACP: A2cp1_2177
ANK: AnaeK_2083(aspA)
SFU: Sfum_0589(aspA) Sfum_1842(aspA) Sfum_2438
ATU: Atu3793(aspA)
ATC: AGR_L_2078
ARA: Arad_8849(aspA)
RET: RHE_PE00351(aspA)
REC: RHECIAT_PA0000281(aspA) RHECIAT_PC0000790(aspA)
RLT: Rleg2_4956(aspA) Rleg2_5752(aspA)
RHI: NGR_b07010(aspA)
BME: BMEI0109(aspA)
BMF: BAB1_1959(aspA)
BMB: BruAb1_1934(aspA)
BMC: BAbS19_I18370(aspA)
BMS: BR1958(aspA)
BMT: BSUIS_A1798(aspA)
BOV: BOV_1884(aspA)
BCS: BCAN_A2003(aspA)
BMR: BMI_I1980(aspA)
BJA: blr1326(aspA)
MEX: Mext_3958
MEA: Mex_1p4341(aspA)
MDI: METDI4950(aspA)
MET: M446_6431(aspA)
MPO: Mpop_4435
MCH: Mchl_4326
MNO: Mnod_2072
MSL: Msil_0461
SIL: SPO2663(aspA)
PDE: Pden_0939(aspA) Pden_1095
BSU: BSU23570(ansB)
BHA: BH1426(aspA)
BAN: BA0609(aspA) BA1800(aspA-2) BA3136(aspA-3)
BAR: GBAA0609(aspA) GBAA1800(aspA-2) GBAA3136(aspA-3)
BAA: BA_1192 BA_2305 BA_3637
BAT: BAS0576(aspA) BAS1667 BAS2915
BAH: BAMEG_1476(aspA3) BAMEG_2792(aspA2) BAMEG_3977(aspA1)
BAI: BAA_0692(aspA1) BAA_1870(aspA2) BAA_3183(aspA3)
BCE: BC0611(aspA) BC1740 BC3093
BCA: BCE_0677(aspA) BCE_1872(aspA)
BCZ: BCZK0520(aspA) BCZK1614(aspA) BCZK2845(aspA)
BCR: BCAH187_A0736(aspA) BCAH187_A1921(aspA2) BCAH187_A3158(aspA3)
BCB: BCB4264_A0647(aspA) BCB4264_A1811(aspA2) BCB4264_A3115(aspA3)
BCU: BCAH820_0665(aspA) BCAH820_1847(aspA2) BCAH820_3135(aspA3)
BCG: BCG9842_B2122(aspA3) BCG9842_B3530(aspA2) BCG9842_B4691(aspA)
BCQ: BCQ_0674(aspA) BCQ_1812(aspA-2) BCQ_2943(ansB)
BCX: BCA_0641(aspA1) BCA_1807(aspA2)
BCY: Bcer98_0526(aspA)
BTK: BT9727_0520(aspA) BT9727_1649(aspA) BT9727_2883(ansB)
BTL: BALH_0548(aspA) BALH_1582(aspA) BALH_2796(aspA)
BWE: BcerKBAB4_0523(aspA) BcerKBAB4_1665
BLI: BL02922(ansB) BL05376(ansB)
BLD: BLi00528(ansB) BLi04139(aspA)
BCL: ABC1732(aspA)
BAY: RBAM_021700(aspA)
BPU: BPUM_3547(ansB2)
GTN: GTNG_2275(aspA)
GYM: GYMC10_0501
AFL: Aflv_2046(aspA)
LSP: Bsph_2697(aspA)
BBE: BBR47_36910(ansA)
LPL: lp_2830(aspA)
LPJ: JDM1_2272(aspA)
LDB: Ldb1750(aspA)
LBU: LBUL_1622(aspA)
LCA: LSEI_2863(aspA)
LCB: LCABL_30650(aspA)
LRH: LGG_02872(ansB)
LRL: LC705_02857(ansB)
LME: LEUM_0153
LCI: LCK_00155
CAC: CAC0274(ansB) CAC1652(aspA)
CTC: CTC00824(aspA)
CBE: Cbei_2342(aspA) Cbei_3220 Cbei_3244(aspA)
CKL: CKL_1546(aspA1) CKL_2331(aspA)
CKR: CKR_1437 CKR_2051
STH: STH833(aspA)
VPR: Vpar_1504
ATE: Athe_0474
DSY: DSY3182(aspA)
DHD: Dhaf_4355
DAE: Dtox_0184
PTH: PTH_0981(aspA)
DAU: Daud_0162(aspA)
FMA: FMG_0521
APR: Apre_0092
TTE: TTE0813(aspA)
TEX: Teth514_0682(aspA)
TPD: Teth39_0244(aspA)
MTA: Moth_1273(aspA)
ADG: Adeg_1240
CSC: Csac_1124(aspA)
NTH: Nther_2667
HOR: Hore_03150
MSM: MSMEG_1677(aspA)
CGL: NCgl1446(aspA)
CGB: cg1697(aspA)
CGT: cgR_1563(aspA) cgR_2809
CEF: CE1633(aspA)
CDI: DIP1254(aspA)
CJK: jk0951(aspA)
CUR: cur_1036(aspA)
CAR: cauri_1255(aspA)
CKP: ckrop_1567
RHA: RHA1_ro02944(aspA) RHA1_ro04453(aspA) RHA1_ro04556(aspA3)
RER: RER_56380(aspA)
ROP: ROP_14510(aspA) ROP_43700(aspA) ROP_44700(aspA)
SMA: SAV_1315(aspA)
LXX: Lxx08930(aspA)
CMI: CMM_2077(aspA)
CMS: CMS_1152(aspA)
ART: Arth_3544 Arth_3976
AAU: AAur_0572(aspA) AAur_3794(aspA)
ACH: Achl_3758
BCV: Bcav_3530
BFA: Bfae_24080
JDE: Jden_1152
PAC: PPA0094(aspA)
NML: Namu_1299
SEN: SACE_2829(aspA) SACE_5071(aspA)
BLO: BL0338(aspA)
BLJ: BLD_1105(aspA)
BLN: Blon_0327(aspA)
BLA: BLA_1013(ansB)
BLC: Balac_1034(aspA)
BLT: Balat_1034(aspA)
TDE: TDE1993(aspA)
LBI: LEPBI_II0048(aspA)
LBF: LBF_4047(aspA)
ABA: Acid345_2689(aspA)
ACA: ACP_1487(aspA)
BTH: BT_2755(aspA)
BFR: BF4213(aspA)
BFS: BF4037(aspA)
BVU: BVU_3880(aspA)
PGI: PG1741(aspA)
PGN: PGN_0377(aspA)
PDI: BDI_0593(aspA)
FJO: Fjoh_3403
FBA: FIC_00580 FIC_00810
COC: Coch_0193
GAU: GAU_0516(aspA) GAU_1984(aspA)
SYP: SYNPCC7002_A2041(aspA)
GVI: glr1457(aspA)
NPU: Npun_F2551(aspA)
RRS: RoseRS_3341
CAG: Cagg_2500
CHL: Chy400_1566
TRO: trd_1469
TMA: TM0444(aspA)
TPT: Tpet_0476(aspA)
TLE: Tlet_1027(aspA)
TRQ: TRQ2_0491(aspA)
TNA: CTN_0228
TNP: Tnap_0226
TME: Tmel_1360
TAF: THA_1505(aspA)
FNO: Fnod_0246(aspA)
KOL: Kole_0398
TYE: THEYE_A1722
NMR: Nmar_1260
Taxonomy
Structures PDB: 1J3U  1JSW  
Reference
  Authors
  Title

  Journal
 1
Ellfolk, N.
Studies on aspartase. 1. Quantitative separation of aspartase from
bacterial cells, and its partial purification.
Acta Chem. Scand. 7 (1953) 824-830.
Other DBs ExplorEnz - The Enzyme Database: 4.3.1.1
IUBMB Enzyme Nomenclature: 4.3.1.1
ExPASy - ENZYME nomenclature database: 4.3.1.1
BRENDA, the Enzyme Database: 4.3.1.1
CAS: 9027-30-9
DBGET integrated database retrieval system