KEGG   ENZYME: 4.3.1.2Help
Entry
EC 4.3.1.2                  Enzyme                                 
Name methylaspartate ammonia-lyase;
beta-methylaspartase;
3-methylaspartase;
L-threo-3-methylaspartate ammonia-lyase
Class Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)
Reaction(IUBMB) L-threo-3-methylaspartate = mesaconate + NH3 [RN:R03696]
Reaction(KEGG) R03696
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Substrate L-threo-3-methylaspartate [CPD:C03618]
Product mesaconate [CPD:C01732];
NH3 [CPD:C00014]
Cofactor Cobamide [CPD:C00210]
Comment A cobalamin protein.
Pathway PATH: ec00660  C5-Branched dibasic acid metabolism
PATH: ec00910  Nitrogen metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K04835  methylaspartate ammonia-lyase
Genes AFM: AFUA_3G00790
AOR: AO090010000710
AFV: AFLA_122010
NFI: NFIA_001410
ECE: Z0892
ECS: ECs0761
ECF: ECH74115_0829
ETW: ECSP_0779
ECM: EcSMS35_0749
ECT: ECIAI39_0701
EUM: ECUMN_0814
EFE: EFER_2378
SES: SARI_02201
YEN: YE4043
SDY: SDY_0673
CKO: CKO_02419
BPE: BP0806 BP3177
BPA: BPP3422 BPP3864
BBR: BB3872 BB4337
MLO: mlr6095
CTC: CTC02563
AMT: Amet_3414
DSY: DSY3233
DHD: Dhaf_4400
DRM: Dred_2689
CHY: CHY_0484 CHY_0582
HOR: Hore_15430
TDE: TDE2235
DTH: DICTH_1229
DTU: Dtur_1344
HAL: VNG2289G(mal)
HSL: OE4207F(mamC)
HMA: rrnAC0687(mal)
HMU: Hmuk_2982
Taxonomy
Structures PDB: 1KCZ  1KD0  1KKO  1KKR  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:13618029]
BARKER HA, SMYTH RD, WAWSZKIEWICZ EJ, LEE MN, WILSON RM.
Enzymic preparation and characterization of an
alpha-L-beta-methylaspartic acid.
Arch. Biochem. Biophys. 78 (1958) 468-76.
Clostridium tetanomorphum
Reference
  Authors
  Title
  Journal
 2
Bright, H.J. and Ingraham, L.L.
The preparation of crystalline beta-methylaspartase.
Biochim. Biophys. Acta 44 (1960) 586-588.
Other DBs ExplorEnz - The Enzyme Database: 4.3.1.2
IUBMB Enzyme Nomenclature: 4.3.1.2
ExPASy - ENZYME nomenclature database: 4.3.1.2
BRENDA, the Enzyme Database: 4.3.1.2
CAS: 9033-26-5
DBGET integrated database retrieval system