| Entry |
|
| Name |
cysteine lyase;
cysteine (sulfite) lyase;
L-cysteine hydrogen-sulfide-lyase (adding sulfite) |
| Class |
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
 |
| Sysname |
L-cysteine hydrogen-sulfide-lyase (adding sulfite;
L-cysteate-forming) |
| Reaction(IUBMB) |
L-cysteine + sulfite = L-cysteate + hydrogen sulfide [RN:R00901] |
| Reaction(KEGG) |
R00901
 |
| Substrate |
L-cysteine [CPD:C00097];
sulfite [CPD:C00094] |
| Product |
L-cysteate [CPD:C00506];
hydrogen sulfide [CPD:C00283] |
| Cofactor |
Pyridoxal phosphate [CPD:C00018] |
| Comment |
A pyridoxal-phosphate protein. Can use a second molecule of cysteine
(producing lanthionine), or other alkyl thiols, as a replacing
agent. |
| Pathway |
PATH: ec00270 Cysteine and methionine metabolism
PATH: ec00430 Taurine and hypotaurine metabolism
PATH: ec01100 Metabolic pathways |
Reference Authors Title
Journal Organism
|
1 [PMID:5813025]
Tolosa EA, Chepurnova NK, Khomutov RM, Severin ES.
Reactions catalysed by cysteine lyase from the yolk sac of chicken
embryo.
Biochim. Biophys. Acta. 171 (1969) 369-71.
Gallus gallus [GN:gga] |
| Other DBs |
ExplorEnz - The Enzyme Database: 4.4.1.10
IUBMB Enzyme Nomenclature: 4.4.1.10
ExPASy - ENZYME nomenclature database: 4.4.1.10
BRENDA, the Enzyme Database: 4.4.1.10
CAS: 9079-86-1 |