KEGG   ENZYME: 4.4.1.14Help
Entry
EC 4.4.1.14                 Enzyme                                 

Name 1-aminocyclopropane-1-carboxylate synthase;
1-aminocyclopropanecarboxylate synthase;
1-aminocyclopropane-1-carboxylic acid synthase;
1-aminocyclopropane-1-carboxylate synthetase;
aminocyclopropanecarboxylic acid synthase;
aminocyclopropanecarboxylate synthase;
ACC synthase;
S-adenosyl-L-methionine methylthioadenosine-lyase
Class Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname S-adenosyl-L-methionine methylthioadenosine-lyase
(1-aminocyclopropane-1-carboxylate-forming)
Reaction(IUBMB) S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate +
methylthioadenosine [RN:R00179]
Reaction(KEGG) R00179
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Substrate S-adenosyl-L-methionine [CPD:C00019]
Product 1-aminocyclopropane-1-carboxylate [CPD:C01234];
methylthioadenosine [CPD:C00170]
Cofactor Pyridoxal phosphate [CPD:C00018]
Comment A pyridoxal-phosphate protein. The enzyme catalyses an
alpha,gamma-elimination.
Pathway PATH: ec00270  Cysteine and methionine metabolism
PATH: ec01070  Biosynthesis of plant hormones
Orthology KO: K01762  1-aminocyclopropane-1-carboxylate synthase
Genes ATH: AT2G22810(ACS4) AT3G49700(ACS9) AT3G61510(ACS1) AT4G37770(ACS8)
     AT5G65800(ACS5)
OSA: 4333976(Os03g0727600) 4336750(Os04g0578000)
OLU: OSTLU_42674
Taxonomy
Structures PDB: 1B8G  1IAX  1IAY  1M4N  1M7Y  1YNU  
Reference
  Authors
  Title

  Journal
1
Boller, T., Herner, R.C. and Kende, H.
Assay for and enzymatic formation of an ethylene precursor,
1-aminocyclopropane-1-carboxylic acid.
Planta 145 (1979) 293-303.
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:507845]
Yu YB, Adams DO, Yang SF.
1-Aminocyclopropanecarboxylate synthase, a key enzyme in ethylene
biosynthesis.
Arch. Biochem. Biophys. 198 (1979) 280-6.
Lycopersicon esculentum [GN:eles]
Other DBs ExplorEnz - The Enzyme Database: 4.4.1.14
IUBMB Enzyme Nomenclature: 4.4.1.14
ExPASy - ENZYME nomenclature database: 4.4.1.14
BRENDA, the Enzyme Database: 4.4.1.14
CAS: 72506-68-4

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