| Entry |
|
| Name |
1-aminocyclopropane-1-carboxylate synthase;
1-aminocyclopropanecarboxylate synthase;
1-aminocyclopropane-1-carboxylic acid synthase;
1-aminocyclopropane-1-carboxylate synthetase;
aminocyclopropanecarboxylic acid synthase;
aminocyclopropanecarboxylate synthase;
ACC synthase;
S-adenosyl-L-methionine methylthioadenosine-lyase |
| Class |
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
 |
| Sysname |
S-adenosyl-L-methionine methylthioadenosine-lyase
(1-aminocyclopropane-1-carboxylate-forming) |
| Reaction(IUBMB) |
S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate +
methylthioadenosine [RN:R00179] |
| Reaction(KEGG) |
R00179
 |
| Substrate |
S-adenosyl-L-methionine [CPD:C00019] |
| Product |
1-aminocyclopropane-1-carboxylate [CPD:C01234];
methylthioadenosine [CPD:C00170] |
| Cofactor |
Pyridoxal phosphate [CPD:C00018] |
| Comment |
A pyridoxal-phosphate protein. The enzyme catalyses an
alpha,gamma-elimination. |
| Pathway |
PATH: ec00270 Cysteine and methionine metabolism
PATH: ec01070 Biosynthesis of plant hormones |
| Orthology |
KO: K01762 1-aminocyclopropane-1-carboxylate synthase |
| Genes |
ATH: AT2G22810(ACS4) AT3G49700(ACS9) AT3G61510(ACS1) AT4G37770(ACS8)
AT5G65800(ACS5)
OSA: 4333976(Os03g0727600) 4336750(Os04g0578000)
OLU: OSTLU_42674
 |
| Structures |
PDB: 1B8G 1IAX 1IAY 1M4N 1M7Y 1YNU |
Reference Authors Title
Journal
|
1
Boller, T., Herner, R.C. and Kende, H.
Assay for and enzymatic formation of an ethylene precursor,
1-aminocyclopropane-1-carboxylic acid.
Planta 145 (1979) 293-303. |
Reference Authors Title
Journal Organism
|
2 [PMID:507845]
Yu YB, Adams DO, Yang SF.
1-Aminocyclopropanecarboxylate synthase, a key enzyme in ethylene
biosynthesis.
Arch. Biochem. Biophys. 198 (1979) 280-6.
Lycopersicon esculentum [GN:eles] |
| Other DBs |
ExplorEnz - The Enzyme Database: 4.4.1.14
IUBMB Enzyme Nomenclature: 4.4.1.14
ExPASy - ENZYME nomenclature database: 4.4.1.14
BRENDA, the Enzyme Database: 4.4.1.14
CAS: 72506-68-4 |