KEGG   ENZYME: 4.6.1.6Help
Entry
EC 4.6.1.6                  Enzyme                                 

Name
cytidylate cyclase;
3',5'-cyclic-CMP synthase;
cytidylyl cyclase;
cytidyl cyclase;
CTP diphosphate-lyase (cyclizing)
Class
Lyases;
Phosphorus-oxygen lyases;
Phosphorus-oxygen lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)
Reaction(IUBMB)
CTP = 3',5'-cyclic CMP + diphosphate [RN:R00574]
Reaction(KEGG)
Substrate
CTP [CPD:C00063]
Product
3',5'-cyclic CMP [CPD:C00941];
diphosphate [CPD:C00013]
History
EC 4.6.1.6 created 1989
Reference
1  [PMID:23778]
  Authors
Cech SY, Ignarro LJ.
  Title
Cytidine 3',5'-monophosphate (cyclic CMP) formation by homogenates of mouse liver.
  Journal
Biochem. Biophys. Res. Commun. 80 (1978) 119-25.
  Organism
Mus musculus
Reference
2
  Authors
Newton, R.P., Salih, S.G., Hakeem, N.A., Kingston, E.E. and Beynon, J.H.
  Title
3',5'-Cyclic UMP, -cyclic IMP, -cyclic TMP and related enzymes in mammalian-tissues.
  Journal
Biochem. Soc. Trans. 13 (1985) 1134-1135.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
65357-82-6

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