KEGG   ENZYME: 5.1.3.19Help
Entry
EC 5.1.3.19                 Enzyme                                 

Name chondroitin-glucuronate 5-epimerase;
polyglucuronate 5-epimerase;
dermatan-sulfate 5-epimerase;
urunosyl C-5 epimerase;
chondroitin D-glucuronosyl 5-epimerase
Class Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname chondroitin-D-glucuronate 5-epimerase
Reaction(IUBMB) chondroitin D-glucuronate = dermatan L-iduronate [RN:R04104]
Reaction(KEGG) R04104
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Substrate chondroitin D-glucuronate
Product dermatan L-iduronate [CPD:C01490]
Comment Not identical with EC 5.1.3.17 heparosan-N-sulfate-glucuronate
5-epimerase.
Pathway PATH: ec00532  Chondroitin sulfate biosynthesis
Orthology KO: K01794  chondroitin-glucuronate 5-epimerase
Genes HSA: 29940(DSE)
PTR: 462957(DSE)
MCC: 716054
MMU: 212898(Dse)
RNO: 365583(Dse)
CFA: 476271(DSE)
BTA: 514028(DSE)
ECB: 100072666(DSE)
MDO: 100022925
GGA: 421745(DSE)
TGU: 100227259
XTR: 100145321
DRE: 568713
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
1  [PMID:7092807]
Malmstrom A, Aberg L.
Biosynthesis of dermatan sulphate. Assay and properties of the
uronosyl C-5 epimerase.
Biochem. J. 201 (1982) 489-93.
Homo sapiens [GN:hsa]
Other DBs ExplorEnz - The Enzyme Database: 5.1.3.19
IUBMB Enzyme Nomenclature: 5.1.3.19
ExPASy - ENZYME nomenclature database: 5.1.3.19
BRENDA, the Enzyme Database: 5.1.3.19
CAS: 70766-66-4

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