| Entry |
|
| Name |
chondroitin-glucuronate 5-epimerase;
polyglucuronate 5-epimerase;
dermatan-sulfate 5-epimerase;
urunosyl C-5 epimerase;
chondroitin D-glucuronosyl 5-epimerase |
| Class |
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
 |
| Sysname |
chondroitin-D-glucuronate 5-epimerase |
| Reaction(IUBMB) |
chondroitin D-glucuronate = dermatan L-iduronate [RN:R04104] |
| Reaction(KEGG) |
R04104
 |
| Substrate |
chondroitin D-glucuronate |
| Product |
dermatan L-iduronate [CPD:C01490] |
| Comment |
Not identical with EC 5.1.3.17 heparosan-N-sulfate-glucuronate
5-epimerase. |
| Pathway |
PATH: ec00532 Chondroitin sulfate biosynthesis |
| Orthology |
KO: K01794 chondroitin-glucuronate 5-epimerase |
| Genes |
HSA: 29940(DSE)
PTR: 462957(DSE)
MCC: 716054
MMU: 212898(Dse)
RNO: 365583(Dse)
CFA: 476271(DSE)
BTA: 514028(DSE)
ECB: 100072666(DSE)
MDO: 100022925
GGA: 421745(DSE)
TGU: 100227259
XTR: 100145321
DRE: 568713
 |
Reference Authors Title
Journal Organism
|
1 [PMID:7092807]
Malmstrom A, Aberg L.
Biosynthesis of dermatan sulphate. Assay and properties of the
uronosyl C-5 epimerase.
Biochem. J. 201 (1982) 489-93.
Homo sapiens [GN:hsa] |
| Other DBs |
ExplorEnz - The Enzyme Database: 5.1.3.19
IUBMB Enzyme Nomenclature: 5.1.3.19
ExPASy - ENZYME nomenclature database: 5.1.3.19
BRENDA, the Enzyme Database: 5.1.3.19
CAS: 70766-66-4 |