| Entry |
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| Name |
methylmalonyl-CoA epimerase;
methylmalonyl-CoA racemase;
methylmalonyl coenzyme A racemase;
DL-methylmalonyl-CoA racemase;
2-methyl-3-oxopropanoyl-CoA 2-epimerase [incorrect]
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| Class |
Isomerases;
Racemases and epimerases;
Acting on other compounds
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| Sysname |
methylmalonyl-CoA 2-epimerase
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| Reaction(IUBMB) |
(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA [RN: R02765]
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| Reaction(KEGG) |
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| Substrate |
(R)-methylmalonyl-CoA [CPD: C01213]
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| Product |
(S)-methylmalonyl-CoA [CPD: C00683]
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| Pathway |
| Valine, leucine and isoleucine degradation | | Glyoxylate and dicarboxylate metabolism | | Propanoate metabolism | | Carbon fixation pathways in prokaryotes | | Metabolic pathways | | Microbial metabolism in diverse environments |
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| Orthology |
| methylmalonyl-CoA/ethylmalonyl-CoA epimerase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | CIN: | | SPU: | | ISC: | | CEL: | | CBR: | | TSP: | | SMM: | | HMG: | | TAD: | | AQU: | | PPP: | | MBR: | | DDI: | | DPP: | | LMA: | | LIF: | | LDO: | | LMI: | | LBZ: | | TVA: | | RAA: | | PPUU: | | PFO: | | PFE: | | PEN: | | GNI: | | SAGA: | | CJB: | | CJN: | | CJI: | | CJP: | | GSU: | | GSK: | | GME: | | GUR: | | GLO: | | GBM: | | GEO: | | GEM: | | GEB: | | PPD: | | BMX: | | DPR: | | DSF: | | DAL: | | DTO: | | ADE: | | ACP: | | AFW: | | ANK: | | SCL: | | SAT: | | DAO: | | DTI: | | DBR: | | HMR: | | MLO: | | MCI: | | MOP: | | MAM: | | MES: | | PLA: | | SME: | | SMK: | | SMQ: | | SMX: | | SMI: | | SMEG: | | SMEL: | | SMD: | | RHI: | | SFH: | | SFD: | | ATU: | | ARA: | | AVI: | | AGR: | | RET: | | REC: | | RLE: | | RLT: | | RLG: | | RTR: | | BME: | | BMI: | | BMZ: | | BMG: | | BMW: | | BMF: | | BMB: | | BMC: | | BAA: | | BMS: | | BSI: | | BMT: | | BSV: | | BOV: | | BCS: | | BSK: | | BMR: | | BPP: | | OAN: | | BJA: | | BJU: | | BRA: | | BBT: | | BRS: | | RPA: | | RPB: | | RPC: | | RPD: | | RPE: | | RPT: | | RPX: | | NWI: | | NHA: | | OCA: | | OCG: | | OCO: | | AOL: | | XAU: | | AZC: | | SNO: | | MEX: | | MEA: | | MDI: | | MCH: | | MRD: | | MET: | | MPO: | | MNO: | | BID: | | MSL: | | HDN: | | HMC: | | RVA: | | PHL: | | MSC: | | CCR: | | CCS: | | CAK: | | CSE: | | PZU: | | BSB: | | SIL: | | SIT: | | RSP: | | RSH: | | RSQ: | | RSK: | | RCP: | | JAN: | | RDE: | | RLI: | | PDE: | | DSH: | | PSF: | | PGA: | | PGL: | | OAT: | | OAR: | | MMR: | | HNE: | | HBA: | | NAR: | | NPP: | | SAL: | | SWI: | | SPHM: | | SJP: | | SCH: | | SSY: | | ELI: | | RRU: | | RRF: | | RCE: | | RPM: | | MAG: | | AZL: | | ALI: | | ABS: | | TMO: | | APB: | | PGV: | | MGM: | | DIN: | | BSU: | | BSR: | | BSL: | | BSH: | | BSY: | | BSS: | | BST: | | BSO: | | BSN: | | BSQ: | | BSUB: | | BSX: | | BAO: | | BAY: | | BAQ: | | BYA: | | BAMP: | | BAML: | | BAZ: | | BQL: | | BXH: | | BQY: | | BAMI: | | BAE: | | BAL: | | BCE: | | BCZ: | | BCX: | | BCF: | | BCER: | | BTK: | | BTL: | | BTB: | | BTT: | | BTF: | | BTI: | | BTN: | | BCL: | | BPF: | | BMQ: | | BMD: | | BMH: | | BJS: | | OIH: | | GKA: | | GTN: | | GTH: | | GTE: | | GWC: | | GYC: | | GYA: | | GCT: | | GMC: | | GGH: | | HHD: | | EAT: | | EAN: | | BBE: | | SIV: | | CTH: | | CBN: | | CLS: | | CST: | | STH: | | DAE: | | DKU: | | PTH: | | DOR: | | DAI: | | CCT: | | ROB: | | SAY: | | SAP: | | THX: | | TBO: | | TWI: | | TEP: | | TAE: | | TOC: | | TXY: | | TSH: | | CPO: | | NTH: | | VPR: | | SSG: | | SRI: | | MHG: | | MPA: | | MAV: | | MIT: | | MIR: | | MIA: | | MID: | | MSM: | | MSG: | | MSA: | | MVA: | | MGI: | | MSP: | | MMV: | | MMC: | | MKM: | | MJL: | | MJD: | | MRH: | | MMM: | | MCB: | | ASD: | | CGU: | | CDP: | | CDH: | | CDT: | | CDE: | | CDR: | | CDA: | | CDZ: | | CDB: | | CDS: | | CDD: | | CDW: | | CDV: | | CKP: | | CPU: | | CPL: | | CPG: | | CPP: | | CPK: | | CPQ: | | CPX: | | CPZ: | | COR: | | COP: | | COD: | | COS: | | COI: | | COE: | | COU: | | CUL: | | CUC: | | CUE: | | NFA: | | NCY: | | NBR: | | RHA: | | RER: | | ROP: | | REQ: | | GBR: | | GPO: | | GOR: | | TPR: | | SCO: | | SMA: | | SGR: | | SCB: | | SSX: | | SVL: | | SCT: | | SCY: | | SFA: | | SBH: | | SHY: | | SHO: | | SVE: | | SDV: | | SALB: | | STRP: | | KSK: | | ART: | | KSE: | | ICA: | | PAC: | | PAK: | | PAV: | | PAX: | | PAZ: | | PAW: | | PAD: | | PCN: | | PACC: | | PACH: | | PFR: | | PPC: | | PBO: | | PRA: | | NCA: | | KFL: | | TFU: | | NDA: | | NAL: | | TCU: | | SRO: | | FRA: | | FRE: | | FRI: | | FAL: | | FSY: | | NML: | | GOB: | | BSD: | | MMAR: | | SEN: | | SVI: | | TBI: | | AMD: | | AMN: | | AMM: | | PDX: | | AMI: | | SESP: | | STP: | | SAQ: | | MAU: | | MIL: | | VMA: | | AMS: | | ASE: | | CAI: | | SNA: | | RXY: | | CWO: | | AFO: | | EYY: | | ABA: | | GMA: | | TSA: | | SUS: | | CTM: | | BTH: | | BFR: | | BFS: | | BFG: | | BHL: | | BSA: | | BXY: | | PGI: | | PGT: | | PAH: | | PPN: | | OSP: | | TFO: | | APS: | | PRU: | | AFD: | | CPI: | | NKO: | | PHE: | | SCN: | | HHY: | | SGN: | | BBD: | | EVI: | | DFE: | | SLI: | | LBY: | | RSI: | | FLI: | | EOL: | | FAE: | | MTT: | | GFO: | | FJO: | | FPS: | | FBR: | | FCO: | | FIN: | | RBI: | | ZPR: | | CAT: | | FBC: | | CAO: | | CLY: | | WVI: | | KDI: | | LAN: | | ZGA: | | MRS: | | ASL: | | PTQ: | | NDO: | | POM: | | FTE: | | OHO: | | IPO: | | OTE: | | CAA: | | AMU: | | IPA: | | SACI: | | TAI: | | ACO: | | TLI: | | AMO: | | SBR: | | CTHE: | | CPC: | | CPH: | | CPB: | | CLI: | | PVI: | | PLT: | | PPH: | | PAA: | | CTS: | | IAL: | | RRS: | | RCA: | | CAU: | | CAG: | | CHL: | | HAU: | | TRO: | | STI: | | ATM: | | CAP: | | DDR: | | DMR: | | DPT: | | DGO: | | DPD: | | TRA: | | TTH: | | TTJ: | | TTS: | | TTL: | | TSC: | | THC: | | TOS: | | MRB: | | MRE: | | MSV: | | OPR: | | MHD: | | TTA: | | FPE: | | PMO: | | KOL: | | MPZ: | | MPG: | | TTR: | | DDF: | | DAP: | | CNI: | | FSI: | | MOX: | | FPL: | | HHI: | | HWA: | | HWC: | | NPH: | | HME: | | HBO: | | PHO: | | PAB: | | PFU: | | PFI: | | PYN: | | PYA: | | PYS: | | TKO: | | TON: | | TGA: | | TSI: | | TBA: | | THE: | | THA: | | THM: | | ABI: | | ACF: | | SSO: | | SOL: | | STO: | | SAI: | | SACN: | | SACR: | | SIS: | | SIA: | | SIM: | | SID: | | SIY: | | SIN: | | SII: | | SIH: | | SIR: | | SIC: | | MSE: | | MCN: | | AHO: | | NMR: | | NIR: | | NKR: | | CSY: | | NGA: | |
» show all
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| Reference |
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| Authors |
MAZUMDER R, SASAKAWA T, KAZIRO Y, OCHOA S. |
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| Title |
Metabolism of propionic acid in animal tissues. IX. Methylmalonyl coenzyme A racemase. |
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| Journal |
J. Biol. Chem. 237 (1962) 3065-8. |
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| Organism |
Propionibacterium shermanii |
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| Reference |
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| Authors |
OVERATH P, KELLERMAN GM, LYNEN F, FRITZ HP, KELLER HJ. |
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| Title |
[On the mechanism of the rearrangement of methylmalonyl-Co A into succinyl-Co A. II. Experiments on the mechanism of action of methylmalonyl-Co A isomerase and methylmalonyl-Co A racemase.] |
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| Journal |
Biochem. Z. 335 (1962) 500-18. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9024-03-7 |
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