KEGG   ENZYME: 5.1.99.1Help
Entry
EC 5.1.99.1                 Enzyme                                 
Name methylmalonyl-CoA epimerase;
methylmalonyl-CoA racemase;
methylmalonyl coenzyme A racemase;
DL-methylmalonyl-CoA racemase;
2-methyl-3-oxopropanoyl-CoA 2-epimerase [incorrect]
Class Isomerases;
Racemases and epimerases;
Acting on other compounds
BRITE hierarchy
Sysname methylmalonyl-CoA 2-epimerase
Reaction(IUBMB) (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA [RN:R02765]
Reaction(KEGG) R02765
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Substrate (R)-methylmalonyl-CoA [CPD:C01213]
Product (S)-methylmalonyl-CoA [CPD:C00683]
Pathway PATH: ec00280  Valine, leucine and isoleucine degradation
PATH: ec00640  Propanoate metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K05606  methylmalonyl-CoA epimerase
Genes HSA: 84693(MCEE)
PTR: 459310(MCEE)
MCC: 704094(MCEE)
MMU: 73724(Mcee)
RNO: 293829(Mcee)
CFA: 479018(MCEE)
BTA: 508170(MCEE) 790465(MCEE)
SSC: 100037986(MCEE)
ECB: 100059601
OAA: 100078740
GGA: 415385(MCEE)
DRE: 553804(mcee)
TVA: TVAG_097630
PFO: Pfl01_2226
GME: Gmet_2237
SAT: SYN_00683 SYN_01971
PLA: Plav_3210
BRA: BRADO4168
BBT: BBta_4545
XAU: Xaut_4617
MEX: Mext_1069
MRD: Mrad2831_2043
MET: M446_4406
MPO: Mpop_1003
MCH: Mchl_1198
SIL: SPO0932
SIT: TM1040_0637
RSP: RSP_0812
RSH: Rsph17029_2469
RSQ: Rsph17025_0368
JAN: Jann_3164
RDE: RD1_1179
DSH: Dshi_2630
HNE: HNE_1762
RRU: Rru_A1572
BCE: BC1837
CTH: Cthe_2225
MAV: MAV_1543(mce)
MSM: MSMEG_4921(mce)
MMC: Mmcs_3865
MJL: Mjls_3851
PAC: PPA1104
NCA: Noca_0160 Noca_1796
TFU: Tfu_2395
FRA: Francci3_2781
SUS: Acid_6046 Acid_6957
CPH: Cpha266_1167
PVI: Cvib_1037
Taxonomy
Structures PDB: 1JC4  1JC5  3GM5  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:13934211]
MAZUMDER R, SASAKAWA T, KAZIRO Y, OCHOA S.
Metabolism of propionic acid in animal tissues. IX. Methylmalonyl
coenzyme A racemase.
J. Biol. Chem. 237 (1962) 3065-8.
Propionibacterium shermanii
Reference
  Authors
  Title


  Journal
 2  [PMID:14482843]
OVERATH P, KELLERMAN GM, LYNEN F, FRITZ HP, KELLER HJ.
[On the mechanism of the rearrangement of methylmalonyl-Co A into
succinyl-Co A. II. Experiments on the mechanism of action of
methylmalonyl-Co A isomerase and methylmalonyl-Co A racemase.]
Biochem. Z. 335 (1962) 500-18.
Other DBs ExplorEnz - The Enzyme Database: 5.1.99.1
IUBMB Enzyme Nomenclature: 5.1.99.1
ExPASy - ENZYME nomenclature database: 5.1.99.1
BRENDA, the Enzyme Database: 5.1.99.1
CAS: 9024-03-7
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