KEGG   ENZYME: 5.3.1.12Help
Entry
EC 5.3.1.12                 Enzyme                                 
Name glucuronate isomerase;
uronic isomerase;
uronate isomerase;
D-glucuronate isomerase;
uronic acid isomerase;
D-glucuronate ketol-isomerase
Class Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds
BRITE hierarchy
Sysname D-glucuronate aldose-ketose-isomerase
Reaction(IUBMB) D-glucuronate = D-fructuronate [RN:R01482]
Reaction(KEGG) R01482;
(other) R01983
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Substrate D-glucuronate [CPD:C00191]
Product D-fructuronate [CPD:C00905]
Comment Also converts D-galacturonate to D-tagaturonate.
Pathway PATH: ec00040  Pentose and glucuronate interconversions
PATH: ec01100  Metabolic pathways
Orthology KO: K01812  glucuronate isomerase
Genes ECO: b3092(uxaC)
ECJ: JW3063(uxaC)
ECD: ECDH10B_3268(uxaC)
EBW: BWG_2802(uxaC)
ECE: Z4445(uxaC)
ECS: ECs3974
ECF: ECH74115_4407(uxaC)
ETW: ECSP_4066(uxaC)
ECG: E2348C_3385(uxaC)
ECC: c3850(uxaC)
ECI: UTI89_C3530(uxaC)
ECP: ECP_3183
ECV: APECO1_3327(uxaC)
ECW: EcE24377A_3560(uxaC)
ECX: EcHS_A3275(uxaC)
ECM: EcSMS35_3384(uxaC)
ECY: ECSE_3373
ECL: EcolC_0608
ECK: EC55989_3506(uxaC)
ECQ: ECED1_3759(uxaC)
ECR: ECIAI1_3238(uxaC)
ECT: ECIAI39_3589(uxaC)
ECZ: ECS88_3488(uxaC)
EUM: ECUMN_3576(uxaC)
ELF: LF82_2402(uxaC)
EBL: B21_02912(uxaC)
EBD: ECBD_0648
EBR: ECB_02961(uxaC)
EOH: ECO103_3837(uxaC)
EOI: ECO111_3914(uxaC)
EOJ: ECO26_4195(uxaC)
EFE: EFER_4383(uxaC)
STY: STY3308(uxaC)
STT: t3058(uxaC)
SPT: SPA3005(uxaC)
SEK: SSPA2803
SPQ: SPAB_03917
SEI: SPC_3205(uxaC)
SEC: SC3078(uxaC)
SEH: SeHA_C3383(uxaC)
SEE: SNSL254_A3389(uxaC)
SEW: SeSA_A3319(uxaC)
SEA: SeAg_B3309(uxaC)
SED: SeD_A3482(uxaC)
SEG: SG3031
SET: SEN2980
SES: SARI_04489
STM: STM3137
YPE: YPO0579(uxaC)
YPK: y3600(uxaC)
YPM: YP_2899(uxaC)
YPA: YPA_3210
YPN: YPN_0447 YPN_0448
YPG: YpAngola_A1104(uxaC)
YPP: YPDSF_0366
YPS: YPTB3478(uxaC)
YPI: YpsIP31758_0491(uxaC)
YPY: YPK_0554
YPB: YPTS_3663
YEN: YE3708(uxaC)
SFL: SF3132(uxaC)
SFX: S3339(uxaC)
SFV: SFV_3133(uxaC)
SSN: SSON_3245(uxaC)
SBO: SBO_2953(uxaC)
SBC: SbBS512_E3528(uxaC)
ECA: ECA0645(uxaC)
PCT: PC1_0529
PWA: Pecwa_0746
PLU: plu0176(uxaC)
PAY: PAU_00126(uxaC)
ENT: Ent638_3546
ESA: ESA_03503
CTU: Ctu_04620(uxaC)
KPN: KPN_03520(uxaC)
KPE: KPK_0591(uxaC)
KPU: KP1_4818(uxaC)
CKO: CKO_03735 CKO_04494
SPE: Spro_4321
EIC: NT01EI_0502
ETR: ETAE_0436(uxaC)
DDA: Dd703_3385
DDC: Dd586_0555 Dd586_2940
DZE: Dd1591_3511
HIT: NTHI0056(uxuC)
HIQ: CGSHiGG_02740
HSO: HS_1602(uxaC)
HSM: HSM_0409
MSU: MS0544(uxaC)
APL: APL_1020(uxaC)
APJ: APJL_1038(uxaC)
APA: APP7_1077
ASU: Asuc_0145
XCC: XCC4117(hrmI)
XCB: XC_4209
XCA: xccb100_4329(uxaC)
XCV: XCV4357(uxaC)
XAC: XAC4251(hrmI)
XOO: XOO4427(hrmI)
XOM: XOO_4170
XOP: PXO_03860(uxaC)
VVU: VV2_1070
VVY: VVA1594
VPA: VPA1706
PPR: PBPRB1515
CJA: CJA_2772(uxaC)
SDE: Sde_0940 Sde_1272
PIN: Ping_0131
TTU: TERTU_0898(uxaC)
MMW: Mmwyl1_2780
TAU: Tola_2882 Tola_3025
GME: Gmet_0451
MLO: mll4056
MES: Meso_4496
SME: SM_b21354(uxaC)
SMD: Smed_4749
AVI: Avi_3892
RET: RHE_CH00090(uxaC)
REC: RHECIAT_CH0000094(uxaC)
RLE: RL0099
RLT: Rleg2_4023
RLG: Rleg_4353
BME: BMEII0476 BMEII0477
BMC: BAbS19_II03990 BAbS19_II04000
BMS: BRA0812
BMT: BSUIS_B0804
BCS: BCAN_B0827(uxaC)
BMR: BMI_II806
AZC: AZC_3342
CCR: CC_1490
CCS: CCNA_01557
CAK: Caul_1756
PZU: PHZ_c2452
SIT: TM1040_3865
RSP: RSP_0488(uxaC)
RSH: Rsph17029_2139
RSQ: Rsph17025_2412
RSK: RSKD131_1820
RDE: RD1_2934(uxaC)
MMR: Mmar10_0230
HBA: Hbal_2766
NAR: Saro_3523 Saro_3677
SAL: Sala_3046
SWI: Swit_1887
BSU: BSU12300(uxaC)
BHA: BH0705
BLI: BL00708(uxaC)
BLD: BLi03516(uxaC)
BCL: ABC0995(uxaC)
BAY: RBAM_012380(uxaC)
BPU: BPUM_2987(uxaC)
OIH: OB0367
GTN: GTNG_1765(uxaC)
GYM: GYMC10_4123
SHA: SH2648
PJD: Pjdr2_2923
LLA: L0019(uxaC)
LLK: LLKF_1710(uxaC) LLKF_1785(uxaC)
LLC: LACR_1742
LLM: llmg_0862(uxaC)
SPH: MGAS10270_Spy1171
SNM: SP70585_2238(uxaC)
SAG: SAG0701(uxaC)
SAN: gbs0674
SAK: SAK_0827(uxaC)
SSU: SSU05_1158 SSU05_1159
SSV: SSU98_1174
SSB: SSUBM407_0783(uxaC)
SSI: SSU1003(uxaC)
SSS: SSUSC84_1041(uxaC)
SEQ: SZO_13120
SEZ: Sez_0689
SEU: SEQ_0716
SUB: SUB1203(uxaC)
SDS: SDEG_1363
LSA: LSA0129(uxaC)
LBR: LVIS_0135 LVIS_0150
LRH: LGG_00054(uxaC) LGG_00055
LRL: LC705_00046(uxaC)
CAC: CAC0692(uxaC)
CPE: CPE0152(uxaC)
CBE: Cbei_1832 Cbei_4082 Cbei_4657
CPY: Cphy_2743
CCE: Ccel_1676
AMT: Amet_1291
ATE: Athe_1402
APR: Apre_1600
EEL: EUBELI_00905
TTE: TTE1939(uxaC)
CSC: Csac_1949
CGL: NCgl2398(cgl2484)
CGB: cg2731(uxaC)
CGT: cgR_2394
CEF: CE2377
LXX: Lxx17350(uxaC)
ART: Arth_0502
AAU: AAur_0527(uxaC)
ACH: Achl_0787
RSA: RSal33209_3421
BCV: Bcav_3312
BFA: Bfae_31050
JDE: Jden_2405
XCE: Xcel_2650
PAC: PPA2329
FRE: Franean1_3197
KRA: Krad_0587
SEN: SACE_5055(hrmI)
SVI: Svir_07080
BLN: Blon_0669
BHY: BHWA1_02239(uxaC)
ABA: Acid345_4306
ACA: ACP_2685(uxaC)
SUS: Acid_5330
BTH: BT_0823
BFR: BF2293
BFS: BF2382(uxaC)
BVU: BVU_3074
PDI: BDI_3184
APS: CFPG_235
RMR: Rmar_2303
DFE: Dfer_4124
CPI: Cpin_5502 Cpin_6832
PHE: Phep_1162
FJO: Fjoh_4262
FBA: FIC_01890
RBI: RB2501_03985
STR: Sterm_0693
SMF: Smon_1307
OTE: Oter_4293
RSD: TGRD_067
NPU: Npun_F5333
TMA: TM0064
TPT: Tpet_0860
TLE: Tlet_1289
TRQ: TRQ2_0883
TNA: CTN_0630
TNP: Tnap_0694
PMO: Pmob_0854
HUT: Huta_0158 Huta_0870
CMA: Cmaq_1622
Taxonomy
Structures PDB: 1J5S  2Q01  3IAC  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:13794771]
ASHWELL G, WAHBA AJ, HICKMAN J.
Uronic acid metabolism in bacteria. I. Purification and properties
of uronic acid isomerase in Escherichia coli.
J. Biol. Chem. 235 (1960) 1559-65.
Escherichia coli [GN:eco]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:14409051]
KILGORE WW, STARR MP.
Catabolism of galacturonic and glucuronic acids by Erwinia
carotovora.
J. Biol. Chem. 234 (1959) 2227-35.
Erwinia carotovora [GN:eca]
Other DBs ExplorEnz - The Enzyme Database: 5.3.1.12
IUBMB Enzyme Nomenclature: 5.3.1.12
ExPASy - ENZYME nomenclature database: 5.3.1.12
BRENDA, the Enzyme Database: 5.3.1.12
CAS: 9023-87-4
DBGET integrated database retrieval system