KEGG   ENZYME: 5.3.3.7Help
Entry
EC 5.3.3.7                  Enzyme                                 

Name
aconitate Delta-isomerase;
aconitate isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Transposing C=C bonds
BRITE hierarchy
Sysname
aconitate Delta2-Delta3-isomerase
Reaction(IUBMB)
trans-aconitate = cis-aconitate [RN:R02244]
Reaction(KEGG)
Substrate
trans-aconitate [CPD:C02341]
Product
cis-aconitate [CPD:C00417]
Comment
cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. This isomerization could take place either in a direct cis-trans interconversion or by an allylic rearrangement; the enzyme has been shown to catalyse the latter change.
History
EC 5.3.3.7 created 1972
Reference
1  [PMID:5114987]
  Authors
Klinman JP, Rose IA.
  Title
Purification and kinetic properties of aconitate isomerase from Pseudomonas putida.
  Journal
Biochemistry. 10 (1971) 2253-9.
  Organism
Pseudomonas putida
Reference
2  [PMID:5114988]
  Authors
Klinman JP, Rose IA.
  Title
Mechanism of the aconitate isomerase reaction.
  Journal
Biochemistry. 10 (1971) 2259-66.
  Organism
Pseudomonas putida
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37318-48-2

DBGET integrated database retrieval system