KEGG   ENZYME: 5.3.99.9Help
Entry
EC 5.3.99.9                 Enzyme                                 

Name
neoxanthin synthase;
NSY
Class
Isomerases;
Intramolecular oxidoreductases;
Other intramolecular oxidoreductases
BRITE hierarchy
Sysname
violaxanthin---neoxanthin isomerase (epoxide-opening)
Reaction(IUBMB)
violaxanthin = neoxanthin [RN:R06948]
Reaction(KEGG)
R06948;
(other) R06951
Show
Substrate
violaxanthin [CPD:C08614]
Product
neoxanthin [CPD:C08606]
Comment
The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].
History
EC 5.3.99.9 created 2005
Pathway
Carotenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K14594  
neoxanthin synthase
Reference
1  [PMID:11094161]
  Authors
Al-Babili S, Hugueney P, Schledz M, Welsch R, Frohnmeyer H, Laule O, Beyer P.
  Title
Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum.
  Journal
FEBS. Lett. 485 (2000) 168-72.
  Organism
Solanum tuberosum
  Sequence
[sot:102601215]
Reference
2  [PMID:11029576]
  Authors
Bouvier F, D'harlingue A, Backhaus RA, Kumagai MH, Camara B.
  Title
Identification of neoxanthin synthase as a carotenoid cyclase paralog.
  Journal
Eur. J. Biochem. 267 (2000) 6346-52.
  Organism
Solanum lycopersicum
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
318960-21-3

DBGET integrated database retrieval system