bisphosphoglycerate mutase;
diphosphoglycerate mutase;
glycerate phosphomutase;
bisphosphoglycerate synthase;
bisphosphoglyceromutase;
biphosphoglycerate synthase;
diphosphoglyceric mutase;
2,3-diphosphoglycerate mutase;
phosphoglyceromutase;
2,3-diphosphoglycerate synthase;
DPGM;
2,3-bisphosphoglycerate mutase;
BPGM;
diphosphoglyceromutase;
2,3-diphosphoglyceromutase

Isomerases;
Intramolecular transferases;
Phosphotransferases (phosphomutases)

3-phospho-D-glycerate 1,2-phosphomutase

3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate [RN:R01662]

R01662

3-phospho-D-glyceroyl phosphate [CPD:C00236]

In the direction shown, this enzyme is phosphorylated by 3-phosphoglyceroyl phosphate, to give phosphoenzyme and 3-phosphoglycerate. The latter is rephosphorylated by the enzyme to yield 2,3-bisphosphoglycerate, but this reaction is slowed by dissociation of 3-phosphoglycerate from the enzyme, which is therefore more active in the presence of added 3-phosphoglycerate. This enzyme also catalyses, slowly, the reactions of EC 3.1.3.13 (bisphosphoglycerate phosphatase) and EC 5.4.2.1 (phosphoglycerate mutase).

1

Ray, W.J., Jr. and Peck, E.J., Jr.

Phosphomutases.

In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.

2  [PMID:5687724]

Rose ZB.

The purification and properties of diphosphoglycerate mutase from human erythrocytes.

J. Biol. Chem. 243 (1968) 4810-20.

Homo sapiens [GN:hsa]

3  [PMID:6255773]

Rose ZB.

The enzymology of 2,3-bisphosphoglycerate.

Adv. Enzymol. Relat. Areas. Mol. Biol. 51 (1980) 211-53.

Homo sapiens [GN:hsa]