| Entry |
|
| Name |
leucine 2,3-aminomutase |
| Class |
Isomerases;
Intramolecular transferases;
Transferring amino groups
 |
| Sysname |
(2S)-alpha-leucine 2,3-aminomutase |
| Reaction(IUBMB) |
(2S)-alpha-leucine = (3R)-beta-leucine [RN:R01091] |
| Reaction(KEGG) |
R01091
 |
| Substrate |
(2S)-alpha-leucine [CPD:C00123] |
| Product |
(3R)-beta-leucine [CPD:C02486] |
| Cofactor |
Cobamide coenzyme [CPD:C00194] |
| Comment |
Requires a cobamide coenzyme. |
| Pathway |
PATH: ec00280 Valine, leucine and isoleucine degradation |
Reference Authors Title
Journal
|
1
Freer, I., Pedrocchi-Fantoni, G., Picken, D.J. and Overton, K.H.
Stereochemistry of the leucine 2,3-aminomutase from tissue-cultures
of Andrographis paniculata.
J. Chem. Soc. Chem. Commun. (1981) 80-82. |
Reference Authors Title Journal Organism
|
2 [PMID:1270414]
Poston JM.
Leucine 2,3-aminomutase, an enzyme of leucine catabolism.
J. Biol. Chem. 251 (1976) 1859-63.
Clostridium sporogenes |
Reference Authors Title
Journal
|
3
Poston, J.M.
Coenzyme B12-dependent enzymes in potatoes: leucine 2,3-aminomutase
and methylmalonyl-CoA mutase.
Phytochemistry 17 (1976) 401-402. |
| Other DBs |
ExplorEnz - The Enzyme Database: 5.4.3.7
IUBMB Enzyme Nomenclature: 5.4.3.7
ExPASy - ENZYME nomenclature database: 5.4.3.7
BRENDA, the Enzyme Database: 5.4.3.7
CAS: 59125-53-0 |