KEGG   ENZYME: 5.4.3.7Help
Entry
EC 5.4.3.7                  Enzyme                                 

Name leucine 2,3-aminomutase
Class Isomerases;
Intramolecular transferases;
Transferring amino groups
BRITE hierarchy
Sysname (2S)-alpha-leucine 2,3-aminomutase
Reaction(IUBMB) (2S)-alpha-leucine = (3R)-beta-leucine [RN:R01091]
Reaction(KEGG) R01091
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Substrate (2S)-alpha-leucine [CPD:C00123]
Product (3R)-beta-leucine [CPD:C02486]
Cofactor Cobamide coenzyme [CPD:C00194]
Comment Requires a cobamide coenzyme.
Pathway PATH: ec00280  Valine, leucine and isoleucine degradation
Reference
  Authors
  Title

  Journal
1
Freer, I., Pedrocchi-Fantoni, G., Picken, D.J. and Overton, K.H.
Stereochemistry of the leucine 2,3-aminomutase from tissue-cultures
of Andrographis paniculata.
J. Chem. Soc. Chem. Commun. (1981) 80-82.
Reference
  Authors
  Title
  Journal
  Organism
2  [PMID:1270414]
Poston JM.
Leucine 2,3-aminomutase, an enzyme of leucine catabolism.
J. Biol. Chem. 251 (1976) 1859-63.
Clostridium sporogenes
Reference
  Authors
  Title

  Journal
3
Poston, J.M.
Coenzyme B12-dependent enzymes in potatoes: leucine 2,3-aminomutase
and methylmalonyl-CoA mutase.
Phytochemistry 17 (1976) 401-402.
Other DBs ExplorEnz - The Enzyme Database: 5.4.3.7
IUBMB Enzyme Nomenclature: 5.4.3.7
ExPASy - ENZYME nomenclature database: 5.4.3.7
BRENDA, the Enzyme Database: 5.4.3.7
CAS: 59125-53-0

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