| Entry |
|
|---|
| Name |
2-acetolactate mutase;
acetolactate mutase;
acetohydroxy acid isomerase |
|---|
| Class |
Isomerases;
Intramolecular transferases;
Transferring other groups
 |
|---|
| Sysname |
2-acetolactate methylmutase |
|---|
| Reaction(IUBMB) |
2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate [RN:R03052] |
|---|
| Reaction(KEGG) |
R03052 > R05071;
(other) R05069
 |
|---|
| Substrate |
2-acetolactate [CPD:C00900] |
|---|
| Product |
3-hydroxy-3-methyl-2-oxobutanoate [CPD:C04181] |
|---|
| Cofactor |
Ascorbate [CPD:C00072] |
|---|
| Comment |
Requires ascorbic acid; also converts 2-aceto-2-hydroxybutanoate to
3-hydroxy-3-methyl-2-oxopentanoate. |
|---|
| Pathway |
PATH: ec00290 Valine, leucine and isoleucine biosynthesis |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4384955]
Allaudeen HS, Ramakrishnan T.
Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis
H37 Rv.
Arch. Biochem. Biophys. 125 (1968) 199-209.
Mycobacterium tuberculosis |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 5.4.99.3
IUBMB Enzyme Nomenclature: 5.4.99.3
ExPASy - ENZYME nomenclature database: 5.4.99.3
BRENDA, the Enzyme Database: 5.4.99.3
CAS: 37318-52-8 |
|---|
