| Entry |
|
| Name |
2-methyleneglutarate mutase;
alpha-methyleneglutarate mutase |
| Class |
Isomerases;
Intramolecular transferases;
Transferring other groups
 |
| Sysname |
2-methyleneglutarate carboxy-methylenemethylmutase |
| Reaction(IUBMB) |
2-methyleneglutarate = 2-methylene-3-methylsuccinate [RN:R03908] |
| Reaction(KEGG) |
R03908
 |
| Substrate |
2-methyleneglutarate [CPD:C02930] |
| Product |
2-methylene-3-methylsuccinate [CPD:C02295] |
| Cofactor |
Cobamide coenzyme [CPD:C00194] |
| Comment |
Requires a cobamide coenzyme. |
| Pathway |
PATH: ec00760 Nicotinate and nicotinamide metabolism |
Reference Authors Title
Journal Organism
|
1 [PMID:5266166]
Kung HF, Cederbaum S, Tsai L, Stadtman TC.
Nicotinic acid metabolism. V. A cobamide coenzyme-dependent
conversion of alpha-methyleneglutaric acid to dimethylmaleic acid.
Proc. Natl. Acad. Sci. U. S. A. 65 (1970) 978-84.
Clostridium |
Reference Authors Title
Journal Organism
|
2 [PMID:5574401]
Kung HF, Stadtman TC.
Nicotinic acid metabolism. VI. Purification and properties of
alpha-methyleneglutarate mutase (B 12-dependent) and methylitaconate
isomerase.
J. Biol. Chem. 246 (1971) 3378-88.
Clostridium barkeri |
| Other DBs |
ExplorEnz - The Enzyme Database: 5.4.99.4
IUBMB Enzyme Nomenclature: 5.4.99.4
ExPASy - ENZYME nomenclature database: 5.4.99.4
BRENDA, the Enzyme Database: 5.4.99.4
CAS: 9059-10-3 |