| Entry |
|
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| Name |
3-carboxy-cis,cis-muconate cycloisomerase;
beta-carboxymuconate lactonizing enzyme;
3-carboxymuconolactone hydrolase |
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| Class |
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
 |
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| Sysname |
2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing) |
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| Reaction(IUBMB) |
2-carboxy-2,5-dihydro-5-oxofuran-2-acetate =
cis,cis-butadiene-1,2,4-tricarboxylate [RN:R03307] |
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| Reaction(KEGG) |
R03307
 |
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| Substrate |
2-carboxy-2,5-dihydro-5-oxofuran-2-acetate [CPD:C01278] |
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| Product |
cis,cis-butadiene-1,2,4-tricarboxylate [CPD:C01163] |
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| Pathway |
PATH: ec00362 Benzoate degradation via hydroxylation
PATH: ec01100 Metabolic pathways |
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| Orthology |
KO: K01857 3-carboxy-cis,cis-muconate cycloisomerase |
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| Genes |
SPO: SPBC8E4.05c
AFV: AFLA_007680
LBC: LACBIDRAFT_237810
MPR: MPER_06834
EFE: EFER_1633(pcaB)
ECA: ECA2842(pcaB)
PCT: PC1_1483
KPN: KPN_01541
KPE: KPK_2913(pcaB)
KPU: KP1_2558
CKO: CKO_03720
SPE: Spro_2505
DDC: Dd586_0016
XCC: XCC0369(pcaB)
XCB: XC_0381
XCA: xccb100_0395(pcaB)
XCV: XCV0383(pcaB)
XAC: XAC0369(pcaB)
XOO: XOO0484(pcaB)
XOM: XOO_0451
XOP: PXO_02908(pcaB)
VVY: VV2243
PAE: PA0230(pcaB)
PAU: PA14_02830(pcaB)
PAP: PSPA7_0316(pcaB)
PAG: PLES_02271(pcaB)
PPU: PP_1379(pcaB)
PPF: Pput_4344
PPG: PputGB1_4435
PPW: PputW619_1019
PST: PSPTO_2341(pcaB)
PSB: Psyr_2125
PSP: PSPPH_2099(pcaB)
PFL: PFL_1323(pcaB)
PFO: Pfl01_1273
PFS: PFLU1369(pcaB)
PEN: PSEEN1167(pcaB)
PSA: PST_1257(pcaB)
AVN: Avin_38190(pcaB)
ACI: ACIAD1707(pcaB)
ACB: A1S_1890
ABM: ABSDF2021(pcaB)
ABY: ABAYE1676(pcaB)
ABC: ACICU_01999
ABN: AB57_2223(pcaB)
ABB: ABBFA_001564(pcaB)
CSA: Csal_0298
RSO: RSc2251(pcaB)
RPI: Rpic_2456
RPF: Rpic12D_2063
REU: Reut_B5023
REH: H16_A2422(pcaB2) H16_B2289(pcaB1)
RME: Rmet_4015
BMA: BMAA0048(pcaB)
BMV: BMASAVP1_1202(pcaB)
BML: BMA10229_1485(pcaB)
BMN: BMA10247_A0058(pcaB)
BPS: BPSS0045(pcaB)
BPM: BURPS1710b_A1555(pcaB)
BPL: BURPS1106A_A0056(pcaB)
BPD: BURPS668_A0069(pcaB)
BTE: BTH_II0048
BVI: Bcep1808_3741
BUR: Bcep18194_B3127
BCN: Bcen_5111
BCH: Bcen2424_5748
BCM: Bcenmc03_4475
BCJ: BCAM0060(pcaB)
BAM: Bamb_5019
BAC: BamMC406_3160
BMU: Bmul_5286
BMJ: BMULJ_03235(purB)
BXE: Bxe_B0645(pcaB) Bxe_B1906
BPH: Bphy_4459
BPY: Bphyt_4314
BGL: bglu_2g00640
BPT: Bpet3489(pcaB1)
RFR: Rfer_0014 Rfer_3487
POL: Bpro_4557
PNA: Pnap_3811
VEI: Veis_4598
DAC: Daci_1439
VAP: Vapar_3324
LCH: Lcho_2418
MLO: mlr7211
MES: Meso_2052 Meso_3622
SME: SM_b20575(pcaB)
SMD: Smed_4210
ATU: Atu4538(pcaB)
ATC: AGR_L_661
ARA: Arad_9505(pcaB)
AVI: Avi_6130(pcaB)
RET: RHE_PE00055(pcaB)
REC: RHECIAT_PA0000059(pcaB)
RLE: pRL110085
RLT: Rleg2_5943
RLG: Rleg_7081
RHI: NGR_b21200(pcaB) NGR_c26380
BME: BMEII0634
BMI: BMEA_B0620(pcaB)
BMF: BAB2_0594
BMB: BruAb2_0579
BMC: BAbS19_II05560
BMS: BRA0647
BCS: BCAN_B0647(pcaB)
BMR: BMI_II644(pcaB)
OAN: Oant_3729
BJA: bll7942(pcaB) blr5667(pcaB)
XAU: Xaut_2685
AZC: AZC_1441
MET: M446_4654
MNO: Mnod_0757
CCR: CC_2410
CCS: CCNA_02493
CAK: Caul_3852
SIL: SPOA0432(pcaB)
SIT: TM1040_0555
RSK: RSKD131_4391
RDE: RD1_3935(pcaB)
DSH: Dshi_3474(pcaB)
SWI: Swit_1071
ACR: Acry_2483
GDI: GDI_3627(pcaB)
GDJ: Gdia_2745
BCG: BCG9842_B4374(purB_1)
MPA: MAP2729c(pcaB)
MAV: MAV_3504(pcaB)
MSM: MSMEG_2603(pcaB)
MVA: Mvan_0562
MGI: Mflv_0528
MAB: MAB_0290
MMC: Mmcs_1700
MJL: Mjls_1678
CGL: NCgl1969(cgl2046) NCgl2313(cgl2396)
CGB: cg2244(pcaB2) cg2629(pcaB1)
CGT: cgR_1934 cgR_2278
CEF: CE2299
RHA: RHA1_ro01337(pcaB)
RER: RER_52880(pcaB)
ROP: ROP_10530(pcaB)
SCO: SCO6698(pcaB)
SMA: SAV_1705(pcaB)
ART: Arth_4076
AAU: AAur_4042
ACH: Achl_3852
KRH: KRH_06060(pcaB)
TCU: Tcur_2457
SRO: Sros_7931
FRA: Francci3_0150
SEN: SACE_3512(pcaB)
SVI: Svir_13030
AMI: Amir_4654
STP: Strop_4409
SAQ: Sare_1055
CAI: Caci_4888
RXY: Rxyl_1579
SUS: Acid_0245
STI: Sthe_0607
DGE: Dgeo_2385
DDR: Deide_1p01310
 |
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| Structures |
PDB: 1Q5N |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:5916392]
Ornston LN.
The conversion of catechol and protocatechuate to beta-ketoadipate
by Pseudomonas putida. II. Enzymes of the protocatechuate pathway.
J. Biol. Chem. 241 (1966) 3787-94.
Pseudomonas putida [GN:ppu] |
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Reference
Authors
Title
Journal
|
2
Ornston, L.N.
Conversion of catechol and protocatechuate to beta-ketoadipate
(Pseudomonas putida).
Methods Enzymol. 17A (1970) 529-549. |
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| Other DBs |
ExplorEnz - The Enzyme Database: 5.5.1.2
IUBMB Enzyme Nomenclature: 5.5.1.2
ExPASy - ENZYME nomenclature database: 5.5.1.2
BRENDA, the Enzyme Database: 5.5.1.2
CAS: 9075-77-8 |
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