KEGG   ENZYME: 6.1.1.18Help
Entry
EC 6.1.1.18                 Enzyme                                 
Name glutamine---tRNA ligase;
glutaminyl-tRNA synthetase;
glutaminyl-transfer RNA synthetase;
glutaminyl-transfer ribonucleate synthetase;
glutamine-tRNA synthetase;
glutamine translase;
glutamate-tRNA ligase;
glutaminyl ribonucleic acid;
GlnRS
Class Ligases;
Forming carbon-oxygen bonds;
Ligases forming aminoacyl-tRNA and related compounds
BRITE hierarchy
Sysname L-glutamine:tRNAGln ligase (AMP-forming)
Reaction(IUBMB) ATP + L-glutamine + tRNAGln = AMP + diphosphate +
L-glutaminyl-tRNAGln [RN:R03652]
Reaction(KEGG) R03652
Show
Substrate ATP [CPD:C00002];
L-glutamine [CPD:C00064];
tRNA(Gln) [CPD:C01640]
Product AMP [CPD:C00020];
diphosphate [CPD:C00013];
L-glutaminyl-tRNA(Gln) [CPD:C02282]
Pathway PATH: ec00970  Aminoacyl-tRNA biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K01886  glutaminyl-tRNA synthetase
Genes HSA: 5859(QARS)
PTR: 743625(QARS)
MCC: 708111(EPRS)
MMU: 97541(Qars)
RNO: 290868(Qars)
CFA: 476628(QARS)
BTA: 514586(QARS)
ECB: 100053641
MDO: 100020835
OAA: 100080102
GGA: 416057(QRICH1)
XLA: 379670
DRE: 394188(qars)
CIN: 100185430
SPU: 580092
DME: Dmel_CG10506(Aats-gln)
DPO: Dpse_GA10360
DAN: Dana_GF17431
DER: Dere_GG12270
DPE: Dper_GL22108
DSE: Dsec_GM17736
DSI: Dsim_GD18218
DYA: Dyak_GE10719
DGR: Dgri_GH22398
DMO: Dmoj_GI24483
AGA: AgaP_AGAP010267
AAG: AaeL_AAEL011395
CQU: CpipJ_CPIJ000734
AME: 413718
NVI: 100123765
TCA: 661180
API: 100160115
ISC: IscW_ISCW000777
CEL: Y41E3.4(ers-1)
CBR: CBG13773
BMY: Bm1_12965
SMM: Smp_148050
NVE: NEMVE_v1g167786
HMG: 100207406
TAD: TRIADDRAFT_37025
ATH: AT1G25350(OVA9)
POP: POPTR_766080
RCU: RCOM_1309310
VVI: 100245668 100258244
OSA: 4325653(Os01g0185200) 4337996(Os05g0182800)
SBI: SORBI_03g003420(SORBIDRAFT_03g003420)
     SORBI_09g005690(SORBIDRAFT_09g005690)
ZMA: 100285944
PPP: PHYPADRAFT_56726
OLU: OSTLU_23867
CME: CMS289C
SCE: YOR168W(GLN4)
AGO: AGOS_AGR259C
KLA: KLLA0F20449g
LTH: KLTH0C10340g
DHA: DEHA0F24277g
PIC: PICST_72287(GLN4)
PPA: PAS_chr3_0285
VPO: Kpol_1037p38
LEL: LELG_05488
ZRO: ZYRO0C07018g
CAL: CaO19.7064(GLN4) CaO19_7064(CaJ7_0069)
CTP: CTRG_05040
CDU: CD36_70110
CGR: CAGL0L04532g
YLI: YALI0C03674g
SPO: SPBC342.02
NCR: NCU07926
PAN: PODANSg409
MGR: MGG_09393
FGR: FG02555.1
ANI: AN9157.2
AFM: AFUA_2G01920
AOR: AO090701000597
ANG: An03g01280
AFV: AFLA_060650
PCS: Pc13g02680
NFI: NFIA_034290
CIM: CIMG_00113
URE: UREG_00221
SSL: SS1G_13818
BFU: BC1G_07401
CNE: CNA00740
CNB: CNBA0720
LBC: LACBIDRAFT_183098
MPR: MPER_05944
UMA: UM05125.1
MGL: MGL_1647
ECU: ECU10_1460
DDI: DDB_0201644(glnS)
EHI: EHI_062700
EDI: EDI_044250
PFA: PF13_0170
PFD: PFDG_02032
PFH: PFHG_02828
PYO: PY02178
PCB: PC000389.03.0
PBE: PB000713.01.0
PKN: PKH_122110
PVX: PVX_082520
TAN: TA12530
TPV: TP02_0322
BBO: BBOV_III006400
CPV: cgd1_2130
CHO: Chro.10244
TET: TTHERM_00056140 TTHERM_00721810
PTM: GSPATT00032125001 GSPATT00035088001
TBR: Tb09.160.3730
TCR: 508277.160
LMA: LmjF15.1440
LIF: LinJ15.1400
LBZ: LbrM15_V2.1430
GLA: GL50803_9348
TVA: TVAG_258380
PTI: PHATRDRAFT_27385
TPS: THAPSDRAFT_13806
ECO: b0680(glnS)
ECJ: JW0666(glnS)
ECD: ECDH10B_0745(glnS)
EBW: BWG_0540(glnS)
ECE: Z0827(glnS)
ECS: ECs0710
ECF: ECH74115_0773(glnS)
ETW: ECSP_0727(glnS)
ECG: E2348C_0571(glnS)
ECC: c0766(glnS)
ECI: UTI89_C0684(glnS)
ECP: ECP_0700
ECV: APECO1_1384(glnS)
ECW: EcE24377A_0706(glnS)
ECX: EcHS_A0725(glnS)
ECM: EcSMS35_0702(glnS)
ECY: ECSE_0741
ECL: EcolC_2976
ECK: EC55989_0666(glnS)
ECQ: ECED1_0661(glnS)
ECR: ECIAI1_0658(glnS)
ECT: ECIAI39_0637(glnS)
ECZ: ECS88_0716(glnS)
EUM: ECUMN_0765(glnS)
ELF: LF82_0856(glnS)
EBL: B21_00628(glnS)
EBD: ECBD_2981
EBR: ECB_00637(glnS)
EOH: ECO103_0676(glnS)
EOI: ECO111_0699(glnS)
EOJ: ECO26_0744(glnS)
EFE: EFER_2429(glnS)
STY: STY0724(glnS)
STT: t2189(glnS)
SPT: SPA2055(glnS)
SEK: SSPA1916
SPQ: SPAB_02856
SEI: SPC_0695(glnS)
SEC: SC0707(glnS)
SEH: SeHA_C0805(glnS)
SEE: SNSL254_A0745(glnS)
SEW: SeSA_A0841(glnS)
SEA: SeAg_B0733(glnS)
SED: SeD_A0792(glnS)
SEG: SG0683(glnS)
SET: SEN0650(glnS)
SES: SARI_02255
STM: STM0686(glnS)
YPE: YPO2630(glnS)
YPK: y1205(glnS)
YPM: YP_1084(glnS2)
YPA: YPA_2467
YPN: YPN_1116
YPG: YpAngola_A0326(glnS)
YPP: YPDSF_2624
YPS: YPTB1121(glnS)
YPI: YpsIP31758_2907(glnS)
YPY: YPK_2994
YPB: YPTS_1179
YEN: YE2977(glnS)
SFL: SF0613(glnS)
SFX: S0624(glnS)
SFV: SFV_0651(glnS)
SSN: SSON_0634(glnS)
SBO: SBO_0542(glnS)
SBC: SbBS512_E0570(glnS)
SDY: SDY_0614(glnS)
ECA: ECA1328(glnS)
PCT: PC1_1205
PWA: Pecwa_3126
ETA: ETA_23290(glnS)
PLU: plu1319(glnS)
PAY: PAU_03085(glnS)
BUC: BU415(glnS)
BAS: BUsg398(glnS)
BAB: bbp375(glnS)
BCC: BCc_263(glnS)
BAP: BUAP5A_408(glnS)
BAU: BUAPTUC7_409(glnS)
WBR: WGLp288(glnS)
SGL: SG0860
ENT: Ent638_1195
ESA: ESA_02658
CTU: Ctu_12960(glnS)
KPN: KPN_00701(glnS)
KPE: KPK_3872(glnS)
KPU: KP1_1653(glnS)
CKO: CKO_02482
SPE: Spro_1229
PMR: PMI0539(glnS)
EIC: NT01EI_2906
ETR: ETAE_2615(glnS)
BFL: Bfl324(glnS)
BPN: BPEN_332(glnS)
HDE: HDEF_0764(glnS)
DDA: Dd703_1116
DDC: Dd586_1161
DZE: Dd1591_2940
HIN: HI1354(glnS)
HIT: NTHI1812(glnS)
HIP: CGSHiEE_04295
HIQ: CGSHiGG_00420
HDU: HD1404(glnS)
HAP: HAPS_0272(glnS)
HSO: HS_0895(glnS)
HSM: HSM_1373
PMU: PM0528(glnS)
MSU: MS1127(glnS)
APL: APL_0679(glnS)
APJ: APJL_0674(glnS)
APA: APP7_0719
ASU: Asuc_1348
AAP: NT05HA_0746
AAT: D11S_1306
XFA: XF1338
XFT: PD0584(glnS)
XFM: Xfasm12_0694
XFN: XfasM23_0613
XCC: XCC0821(glnS)
XCB: XC_3409
XCA: xccb100_3531
XCV: XCV0930(glnS)
XAC: XAC0893(glnS)
XOO: XOO3713(glnS)
XOM: XOO_3505
XOP: PXO_04610(glnS)
SML: Smlt0832(glnS)
SMT: Smal_0682
VCH: VC0997
VCO: VC0395_A0517(glnS)
VCM: VCM66_0953(glnS)
VCJ: VCD_003341
VVU: VV1_0176 VV1_0177
VVY: VV1013
VPA: VP0832
VHA: VIBHAR_01337
VSP: VS_2259
VEX: VEA_004127
VFI: VF_0809(glnS)
VFM: VFMJ11_0847(glnS)
VSA: VSAL_I0832(glnS)
PPR: PBPRA1034
PAE: PA1794(glnS)
PAU: PA14_41380(glnS)
PAP: PSPA7_3509(glnS)
PAG: PLES_35351(glnS)
PPU: PP_2904(glnS)
PPF: Pput_2787
PPG: PputGB1_2879
PPW: PputW619_2406
PST: PSPTO_3743(glnS)
PSB: Psyr_1734
PSP: PSPPH_1678(glnS)
PFL: PFL_3913(glnS)
PFO: Pfl01_3639
PFS: PFLU3872
PEN: PSEEN2086(glnS)
PMY: Pmen_2572
PSA: PST_2052(glnS)
CJA: CJA_1681(glnS)
AVN: Avin_23520(glnS)
PAR: Psyc_0694(glnS)
PCR: Pcryo_0665
PRW: PsycPRwf_0814
ACI: ACIAD1920(glnS)
ACB: A1S_2108
ABM: ABSDF1631(glnS)
ABY: ABAYE1455(glnS)
ABC: ACICU_02304
ABN: AB57_2440(glnS)
ABB: ABBFA_001359(glnS)
SON: SO_1786(glnS)
SDN: Sden_2413
SFR: Sfri_2615
SAZ: Sama_1216
SBL: Sbal_1596
SBM: Shew185_1585
SBN: Sbal195_1619
SBP: Sbal223_2758
SLO: Shew_2516
SPC: Sputcn32_1482
SSE: Ssed_1533
SPL: Spea_2689
SHE: Shewmr4_2503
SHM: Shewmr7_2571
SHN: Shewana3_2669
SHW: Sputw3181_2619
SHL: Shal_2775
SWD: Swoo_3121
SWP: swp_3269
ILO: IL1478(glnS)
CPS: CPS_3240(glnS)
PHA: PSHAa1642(glnS)
PAT: Patl_2184
SDE: Sde_1902
MAQ: Maqu_1845
AMC: MADE_01892
PIN: Ping_0492
TTU: TERTU_1907(glnS)
LPN: lpg1306(glnS)
LPF: lpl1269(glnS)
LPP: lpp1270(glnS)
LPC: LPC_0731(glnS)
FTU: FTT_0448c(glnS)
FTF: FTF0448c(glnS)
FTW: FTW_1622(glnS)
FTL: FTL_1617
FTH: FTH_1564(glnS)
FTA: FTA_1705(glnS)
FTM: FTM_1455(glnS)
FTN: FTN_0539(glnS)
FPH: Fphi_0298
TCX: Tcr_0922
HNA: Hneap_1220
HCH: HCH_02153(glnS)
CSA: Csal_2052
ABO: ABO_1207(glnS)
MMW: Mmwyl1_2109
AHA: AHA_1529(glnS)
ASA: ASA_2825(glnS)
TAU: Tola_2134
DNO: DNO_1108(glnS)
BCI: BCI_0094(glnS)
CRP: CRP_071
RMA: Rmag_0909
VOK: COSY_0816(glnS)
KKO: Kkor_0486
NMA: NMA1748(glnS)
NME: NMB1560(glnS)
NMC: NMC1478(glnS)
NMN: NMCC_1462(glnS)
NMI: NMO_1370(glnS1)
NGO: NGO1218
NGK: NGK_0294
CVI: CV_1742(glnS)
LHK: LHK_01404(syq)
RSO: RSc0791(glnS)
RPI: Rpic_0737
RPF: Rpic12D_0807
REU: Reut_A0833
REH: H16_A2784(glnS)
RME: Rmet_0818
CTI: RALTA_A2274(glnS)
BMA: BMA0892(glnS)
BMV: BMASAVP1_A1419(glnS)
BML: BMA10229_A0459(glnS)
BMN: BMA10247_0701(glnS)
BPS: BPSL2012(glnS)
BPM: BURPS1710b_1812(glnS)
BPL: BURPS1106A_1655(glnS)
BPD: BURPS668_1633(glnS)
BPR: GBP346_A1681(glnS)
BTE: BTH_I2665(glnS)
BVI: Bcep1808_1369
BUR: Bcep18194_A4549
BCN: Bcen_0923
BCH: Bcen2424_1405
BCM: Bcenmc03_1383
BCJ: BCAL1413(glnS)
BAM: Bamb_1282
BAC: BamMC406_1316
BMU: Bmul_1910
BMJ: BMULJ_01331(glnS)
BXE: Bxe_A1307
BPH: Bphy_0907
BPY: Bphyt_2828
BGL: bglu_1g22250
PNU: Pnuc_1722
PNE: Pnec_1440
BPE: BP3226(glnS)
BPA: BPP3578(glnS)
BBR: BB4013(glnS)
BPT: Bpet0894(glnS)
BAV: BAV2787(glnS)
RFR: Rfer_1823
POL: Bpro_3350
PNA: Pnap_1351
AAV: Aave_2300
AJS: Ajs_1608
VEI: Veis_4234
DAC: Daci_2489
DIA: Dtpsy_2106
VAP: Vapar_3615
CTT: CtCNB1_3311
MPT: Mpe_A1314
HAR: HEAR0612(glnS)
MMS: mma_0579(glnS)
LCH: Lcho_1956
NEU: NE2356(glnS) NE2363(glnS)
NET: Neut_0871
NMU: Nmul_A2083
EBA: ebA4065(glnS)
AZO: azo0836(glnS)
DAR: Daro_3447
TBD: Tbd_0850
MFA: Mfla_2082
MMB: Mmol_0662
MEI: Msip34_0651
APP: CAP2UW1_4243
SDL: Sdel_0681
SUN: SUN_1139(glnS)
GSU: GSU3366(glnS)
GME: Gmet_0058
GUR: Gura_4167
GLO: Glov_2128
GBM: Gbem_3799
GEO: Geob_0558
GEM: GM21_3882
PCA: Pcar_0101(glnS)
PPD: Ppro_1725
DVU: DVU2951(glnS)
DVL: Dvul_0417
DVM: DvMF_1485
DDE: Dde_0626
DDS: Ddes_0267
DMA: DMR_44510(glnS)
DSA: Desal_3018
LIP: LI0493(glnS)
DBA: Dbac_0536
DRT: Dret_1384
BBA: Bd1371(glnS)
DPS: DP2738
DOL: Dole_1595
DAL: Dalk_3446
DAT: HRM2_23310(glnS)
ADE: Adeh_2599
ACP: A2cp1_1350
AFW: Anae109_1263
ANK: AnaeK_1249
MXA: MXAN_2363(glnS)
SCL: sce_pseudo_15
HOH: Hoch_6655
SAT: SYN_02116
SFU: Sfum_3516
BJA: bll4837(glnS)
BRA: BRADO4124(glnS)
BBT: BBta_4500(glnS)
RPA: RPA2905(glnS)
RPB: RPB_2811
RPC: RPC_2452
RPD: RPD_2841
RPE: RPE_2569
RPT: Rpal_3251
NWI: Nwi_1843
NHA: Nham_1710
OCA: OCAR_5973(glnS)
GYM: GYMC10_5941
BBE: BBR47_55490(glnS)
PJD: Pjdr2_5868
CPE: CPE0645(gltX)
CPF: CPF_0626(glnS)
CPR: CPR_0612(glnS)
CNO: NT01CX_0275(glnS)
CTH: Cthe_0917
CDF: CD2059(glnS)
CDC: CD196_1923(glnS)
CDL: CDR20291_1966(glnS)
CBE: Cbei_1429
CKL: CKL_1022(glnS)
CKR: CKR_0926
CPY: Cphy_3294
AMT: Amet_4254
AOE: Clos_0176
SWO: Swol_2459
VPR: Vpar_1277
DSY: DSY4982
DHD: Dhaf_4882
DRM: Dred_0189
DAE: Dtox_3791
PTH: PTH_2867(glnS)
HMO: HM1_1023(glnS)
EEL: EUBELI_00503
ERE: EUBREC_1603
POY: PAM620(glnS)
AYW: AYWB_116(glnS)
PML: ATP_00201(glnS)
PAL: PAa_0694(glnS)
ACL: ACL_1352(glnS)
PAC: PPA1870
SUS: Acid_5012
BTH: BT_1325
BFR: BF2758
BFS: BF2773(glnS)
BVU: BVU_3941
PGI: PG1951(glnS)
PGN: PGN_1883
PDI: BDI_1388
APS: CFPG_340
SRU: SRU_1795
DFE: Dfer_2503
CPI: Cpin_0242
PHE: Phep_4241
GFO: GFO_3307(glnS)
FJO: Fjoh_1012
FPS: FP2494(glnS)
FBA: FIC_01899
COC: Coch_1133
RBI: RB2501_06855
SMG: SMGWSS_023(glnS)
SMS: SMDSEM_026(glnS)
BBL: BLBBGE_181(glnS)
BPI: BPLAN_454(glnS)
FSU: Fisuc_0426
OTE: Oter_3674
AMU: Amuc_0421
GAU: GAU_2690(glnS)
RBA: RB1578(glnS)
TAI: Taci_1596
DRA: DR_2611
DGE: Dgeo_2188
DDR: Deide_01150(glnS)
TTH: TTC0181
TTJ: TTHA0549
Taxonomy
Structures PDB: 1EUQ  1EUY  1EXD  1GSG  1GTR  1GTS  1NYL  1O0B  1O0C  1QRS  
     1QRT  1QRU  1QTQ  1ZJW  2HZ7  2RD2  2RE8  
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:14253448]
RAVEL JM, WANG SF, HEINEMEYER C, SHIVE W.
GLUTAMYL AND GLUTAMINYL RIBONUCLEIC ACID SYNTHETASES OF ESCHERICHIA
COLI W. SEPARATION, PROPERTIES, AND STIMULATION OF ADENOSINE
TRIPHOSPHATE-PYROPHOSPHATE EXCHANGE BY ACCEPTOR RIBONUCLEIC ACID.
J. Biol. Chem. 240 (1965) 432-8.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 6.1.1.18
IUBMB Enzyme Nomenclature: 6.1.1.18
ExPASy - ENZYME nomenclature database: 6.1.1.18
BRENDA, the Enzyme Database: 6.1.1.18
CAS: 9075-59-6
DBGET integrated database retrieval system