| Entry |
|
|---|
| Name |
biotin---CoA ligase;
biotinyl-CoA synthetase;
biotin CoA synthetase;
biotinyl coenzyme A synthetase |
|---|
| Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
 |
|---|
| Sysname |
biotin:CoA ligase (AMP-forming) |
|---|
| Reaction(IUBMB) |
ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA [RN:R01075] |
|---|
| Reaction(KEGG) |
R01075;
(other) R01074 R03762
 |
|---|
| Substrate |
ATP [CPD:C00002];
biotin [CPD:C00120];
CoA [CPD:C00010] |
|---|
| Product |
AMP [CPD:C00020];
diphosphate [CPD:C00013];
biotinyl-CoA [CPD:C01894] |
|---|
| Pathway |
PATH: ec00780 Biotin metabolism
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14257635]
CHRISTNER JE, SCHLESINGER MJ, COON MJ.
ENZYMATIC ACTIVATION OF BIOTIN. BIOTINYL ADENYLATE FORMATION.
J. Biol. Chem. 239 (1964) 3997-4005.
Sus scofa [GN:ssc] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 6.2.1.11
IUBMB Enzyme Nomenclature: 6.2.1.11
ExPASy - ENZYME nomenclature database: 6.2.1.11
BRENDA, the Enzyme Database: 6.2.1.11
CAS: 37318-60-8 |
|---|
