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Entry
EC 6.2.1.20                 Enzyme                                 
Name long-chain-fatty-acid---[acyl-carrier-protein] ligase;
acyl-[acyl-carrier-protein] synthetase;
acyl-[acyl carrier protein] synthetase;
acyl-ACP synthetase;
acyl-[acyl-carrier-protein]synthetase;
stearoyl-ACP synthetase;
acyl-acyl carrier protein synthetase;
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Class Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname long-chain-fatty-acid:[acyl-carrier protein] ligase (AMP-forming)
Reaction(IUBMB) ATP + an acid + an [acyl-carrier protein] = AMP + diphosphate + an
acyl-[acyl-carrier protein] [RN:R07325]
Reaction(KEGG) R07325 > R01406
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Substrate ATP [CPD:C00002];
acid [CPD:C00174];
[acyl-carrier protein] [CPD:C00229]
Product AMP [CPD:C00020];
diphosphate [CPD:C00013];
acyl-[acyl-carrier protein] [CPD:C00173]
Comment Not identical with EC 6.2.1.3 long-chain-fatty-acid---CoA ligase.
Pathway PATH: ec00071  Fatty acid metabolism
Orthology KO: K01909  long-chain-fatty-acid--[acyl-carrier-protein] ligase
Genes ECO: b2836(aas)
ECJ: JW2804(aas)
ECD: ECDH10B_3006(aas)
EBW: BWG_2572(aas)
ECE: Z4154(aas)
ECS: ECs3693
ECF: ECH74115_4103(aas)
ETW: ECSP_3789(aas)
ECG: E2348C_3106(aas)
ECC: c3431(aas)
ECI: UTI89_C3240(aas)
ECP: ECP_2849
ECV: APECO1_3670(aas)
ECW: EcE24377A_3156(aas)
ECX: EcHS_A2983(aas)
ECM: EcSMS35_2984(aas)
ECY: ECSE_3093
ECL: EcolC_0879
ECK: EC55989_3112(aas)
ECQ: ECED1_3292(aas)
ECR: ECIAI1_2945(aas)
ECT: ECIAI39_3256(aas)
ECZ: ECS88_3131(aas)
EUM: ECUMN_3163(aas)
ELF: LF82_0005(aas)
EBL: B21_02645(aas)
EBD: ECBD_0888
EBR: ECB_02684(aas)
EOH: ECO103_3396(aas)
EOI: ECO111_3565(aas)
EOJ: ECO26_3909(aas)
EFE: EFER_2770(aas)
STY: STY3153(aas)
STT: t2919(aas)
SPT: SPA2875(aas)
SEK: SSPA2680
SPQ: SPAB_03746
SEI: SPC_3068(aas)
SEC: SC2949(aas)
SEH: SeHA_C3223
SEE: SNSL254_A3238
SEW: SeSA_A3175
SEA: SeAg_B3157
SED: SeD_A3338
SEG: SG2919(aas)
SET: SEN2853(aas)
SES: SARI_04649
STM: STM3010(aas)
YPE: YPO0793(aas)
YPK: y3181(aas)
YPM: YP_2864(aas)
YPA: YPA_0476
YPN: YPN_2996
YPG: YpAngola_A3246(aas)
YPP: YPDSF_1710
YPS: YPTB3042(aas)
YPI: YpsIP31758_0975(aas)
YPY: YPK_1027
YPB: YPTS_3164
YEN: YE3327(aas)
SFL: SF2846(aas)
SFX: S3044(aas)
SFV: SFV_2914(aas)
SSN: SSON_2996(aas)
SBO: SBO_2728(aas)
SBC: SbBS512_E3026(aas)
SDY: SDY_3053(aas)
ECA: ECA3641(aas)
PCT: PC1_3463
PWA: Pecwa_3617
ETA: ETA_27680(aas)
PLU: plu1246(aas)
PAY: PAU_03215
ENT: Ent638_3277
ESA: ESA_00472
CTU: Ctu_33860(aas)
KPN: KPN_03245(aas)
KPE: KPK_0869(aas)
KPU: KP1_4517(aas)
CKO: CKO_04208
SPE: Spro_3830
PMR: PMI0372(aas)
EIC: NT01EI_3265
ETR: ETAE_2889(aas)
DDA: Dd703_0766
DDC: Dd586_3401
DZE: Dd1591_0750
AAP: NT05HA_0762
AAT: D11S_1320
PSP: PSPPH_1569(aas)
AVN: Avin_01340
SDE: Sde_3531
LPN: lpg0597(aas)
LPF: lpl0631
LPP: lpp0647
LPC: LPC_2703
TCX: Tcr_0070
TAU: Tola_3171
NET: Neut_2466
AZO: azo0150(aas)
DAR: Daro_0402
MMB: Mmol_2298
MEI: Msip34_2773
HHE: HH0306
CJE: Cj0938c(aas)
CJR: CJE1016(aas)
CJJ: CJJ81176_0955(aas)
CJU: C8J_0881(aas)
CCV: CCV52592_0888
CHA: CHAB381_1726
CCO: CCC13826_1923
CLA: Cla_0921(aas)
ABU: Abu_0193(aas)
SUN: SUN_1164
GSU: GSU3029
GME: Gmet_0086
GLO: Glov_1106
GBM: Gbem_0302
GEO: Geob_0075
GEM: GM21_0285
PCA: Pcar_2776
PPD: Ppro_3365
DBA: Dbac_1480
RPR: RP620
RTY: RT0611(aas)
RCM: A1E_01650
RCO: RC0962(aas)
RFE: RF_0417(aas)
RAK: A1C_04875
RRI: A1G_05280
RRJ: RrIowa_1138
RMS: RMA_0988(aas)
RPK: RPR_07235
RAF: RAF_ORF0865(aas)
RBE: RBE_0465(aas)
RBO: A1I_05365
OTS: OTBS_1706(aas)
OTT: OTT_1948(aas)
MLO: mlr5451
RET: RHE_CH01022(aas)
REC: RHECIAT_CH0001121(aas)
RLE: RL1108
RLT: Rleg2_0679
RLG: Rleg_0737
BJA: bll2324
BRA: BRADO5289
BBT: BBta_5738
MEX: Mext_1501
MEA: Mex_1p1393
MDI: METDI2163
MRD: Mrad2831_0910
MET: M446_4578
MPO: Mpop_1502
MCH: Mchl_1780
MNO: Mnod_4512
BID: Bind_0852
MSL: Msil_0197
CCR: CC_1733
CCS: CCNA_01807
CAK: Caul_2753
PZU: PHZ_c1738
MMR: Mmar10_1427
HNE: HNE_2022(aas)
HBA: Hbal_1669
GBE: GbCGDNIH1_2359
MAG: amb2972
BBE: BBR47_56710(aas)
AAC: Aaci_2452
DAE: Dtox_3826
HMO: HM1_2787(aas)
MTU: Rv1345(fadD33)
MTC: MT1387
MRA: MRA_1353(fadD33)
MTF: TBFG_11375
MTB: TBMG_02633(TBMG_02633.1)
MBO: Mb1380(fadD33)
MBB: BCG_1407(fadD33)
MBT: JTY_1381(fadD33)
MPA: MAP0026(fadD33_1) MAP1554c(fadD33_2)
MAV: MAV_0030 MAV_2874
MSM: MSMEG_2131
MVA: Mvan_1945
MGI: Mflv_4411
MMC: Mmcs_1723 Mmcs_2342
MKM: Mkms_1770 Mkms_2389
MJL: Mjls_1702 Mjls_2383
CTR: CT776(aas)
CTA: CTA_0846(aas)
CTB: CTL0145(aas)
CTL: CTLon_0145(aas)
CTJ: JALI_7811(aas)
CMU: TC0157
CPN: CPn0922(aas)
CPA: CP0944
CPJ: CPj0922(aas)
CPT: CpB0954
CCA: CCA00847
CAB: CAB812
CFE: CF0169(aas)
PCU: pc1236(aas)
FSU: Fisuc_2797
OTE: Oter_3921
MIN: Minf_1750(caiC)
AMU: Amuc_1720
RBA: RB6533(aas)
EMI: Emin_1012
AAE: aq_2058(aas)
Taxonomy
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:794875]
Ray TK, Cronan JE Jr.
Activation of long chain fatty acids with acyl carrier protein:
demonstration of a new enzyme, acyl-acyl carrier protein synthetase,
in Escherichia coli.
Proc. Natl. Acad. Sci. U. S. A. 73 (1976) 4374-8.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 6.2.1.20
IUBMB Enzyme Nomenclature: 6.2.1.20
ExPASy - ENZYME nomenclature database: 6.2.1.20
BRENDA, the Enzyme Database: 6.2.1.20
CAS: 77322-37-3
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