| Entry |
|
|---|
| Name |
glutarate---CoA ligase;
glutaryl-CoA synthetase;
glutaryl coenzyme A synthetase |
|---|
| Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
 |
|---|
| Sysname |
glutarate:CoA ligase (ADP-forming) |
|---|
| Reaction(IUBMB) |
ATP + glutarate + CoA = ADP + phosphate + glutaryl-CoA [RN:R02402] |
|---|
| Reaction(KEGG) |
R02402
 |
|---|
| Substrate |
ATP [CPD:C00002];
glutarate [CPD:C00489];
CoA [CPD:C00010] |
|---|
| Product |
ADP [CPD:C00008];
phosphate [CPD:C00009];
glutaryl-CoA [CPD:C00527] |
|---|
| Comment |
GTP or ITP can act instead of ATP. |
|---|
| Pathway |
PATH: ec00071 Fatty acid metabolism
PATH: ec00310 Lysine degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13769477]
MENON GK, FRIEDMAN DL, STERN JR.
Enzymic synthesis of glutaryl-coenzyme A.
Biochim. Biophys. Acta. 44 (1960) 375-7.
Canis familiaris [GN:cfa], Rattus norvegicus [GN:rno], pigeon |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 6.2.1.6
IUBMB Enzyme Nomenclature: 6.2.1.6
ExPASy - ENZYME nomenclature database: 6.2.1.6
BRENDA, the Enzyme Database: 6.2.1.6
CAS: 9023-68-1 |
|---|
