KEGG   ENZYME: 6.3.2.4Help
Entry
EC 6.3.2.4                  Enzyme                                 
Name D-alanine---D-alanine ligase;
MurE synthetase [ambiguous];
alanine:alanine ligase (ADP-forming);
alanylalanine synthetase
Class Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
BRITE hierarchy
Sysname D-alanine:D-alanine ligase (ADP-forming)
Reaction(IUBMB) ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine [RN:R01150]
Reaction(KEGG) R01150
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Substrate ATP [CPD:C00002];
D-alanine [CPD:C00133]
Product ADP [CPD:C00008];
phosphate [CPD:C00009];
D-alanyl-D-alanine [CPD:C00993]
Inhibitor Phosphinate [CPD:C05339]
Comment Involved with EC 6.3.2.7
(UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase) or EC
6.3.2.13
(UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate
ligase), EC 6.3.2.8 (UDP-N-acetylmuramate---L-alanine ligase), EC
6.3.2.9 (UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase) and EC
6.3.2.10 (UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine
ligase) in the synthesis of a cell-wall peptide (click here for
diagram).
Pathway PATH: ec00473  D-Alanine metabolism
PATH: ec00550  Peptidoglycan biosynthesis
Orthology KO: K01921  D-alanine-D-alanine ligase
Genes ECO: b0092(ddlB) b0381(ddlA)
ECJ: JW0090(ddlB) JW0372(ddlA)
ECD: ECDH10B_0074(ddl) ECDH10B_0338(ddl)
EBW: BWG_0087(ddlB) BWG_0265(ddlA)
ECE: Z0102(ddl) Z0477(ddl)
ECS: ECs0096(ddl) ECs0431(ddl)
ECF: ECH74115_0100(ddl) ECH74115_0453(ddl)
ETW: ECSP_0095(ddlB) ECSP_0441(ddlA)
ECG: E2348C_0097(ddl) E2348C_0317(ddl)
ECC: c0110(ddl) c0487(ddl)
ECI: UTI89_C0101(ddl) UTI89_C0398(ddl)
ECP: ECP_0094(ddl) ECP_0440(ddl)
ECV: APECO1_1627(ddl) APECO1_1894(ddl)
ECW: EcE24377A_0094(ddl) EcE24377A_0406(ddl)
ECX: EcHS_A0098(ddl) EcHS_A0447(ddl)
ECM: EcSMS35_0097(ddl) EcSMS35_0410(ddl)
ECY: ECSE_0094(ddl) ECSE_0401(ddl)
ECL: EcolC_3251(ddl) EcolC_3565(ddl)
ECK: EC55989_0088(ddl) EC55989_0386(ddl)
ECQ: ECED1_0093(ddl) ECED1_0404(ddl)
ECR: ECIAI1_0091(ddl) ECIAI1_0377(ddl)
ECT: ECIAI39_0095(ddl) ECIAI39_0301(ddl)
ECZ: ECS88_0095(ddl) ECS88_0375(ddl)
EUM: ECUMN_0092(ddl) ECUMN_0418(ddl)
ELF: LF82_0455(ddlA) LF82_0456(ddlB)
EBL: B21_00092(ddl)
EBD: ECBD_3283 ECBD_3525
EBR: ECB_00093(ddlB) ECB_00328(ddlA)
EOH: ECO103_0094(ddlB) ECO103_0356(ddlA)
EOI: ECO111_0095(ddlB) ECO111_0411(ddlA)
EOJ: ECO26_0095(ddlB) ECO26_0414(ddlA)
EFE: EFER_0114(ddl) EFER_2642(ddlA)
STY: STY0150(ddl) STY0412(ddl)
STT: t0134(ddl) t2484(ddl)
SPT: SPA0132(ddl)
SEK: SSPA0128(ddl)
SPQ: SPAB_00164(ddl) SPAB_03212(ddl)
SEI: SPC_0139(ddl) SPC_0390(ddl)
SEC: SC0127(ddl) SC0421(ddl)
SEH: SeHA_C0142(ddl) SeHA_C0476(ddl)
SEE: SNSL254_A0142(ddl) SNSL254_A0422(ddl)
SEW: SeSA_A0146(ddl) SeSA_A0434(ddl)
SEA: SeAg_B0147(ddl) SeAg_B0416(ddl)
SED: SeD_A0139(ddl) SeD_A0415(ddl)
SEG: SG0131(ddl) SG0392(ddl)
SET: SEN0131(ddl) SEN0363(ddl)
SES: SARI_02546(ddl) SARI_02871(ddl)
STM: STM0130(ddl) STM0380(ddl)
YPE: YPO0557(ddl)
YPK: y3624(ddl)
YPM: YP_3627(ddl)
YPA: YPA_3544(ddl)
YPN: YPN_0423(ddl)
YPG: YpAngola_A2916(ddl)
YPP: YPDSF_3085(ddl)
YPS: YPTB0690(ddl)
YPI: YpsIP31758_3385(ddl)
YPY: YPK_3516(ddl)
YPB: YPTS_0717(ddl)
YEN: YE0674(ddl) YE3211(ddlA)
SFL: SF0089(ddl) SF0232(ddl)
SFX: S0091(ddl) S0254(ddl)
SFV: SFV_0085(ddl) SFV_0344(ddl)
SSN: SSON_0100(ddl) SSON_0356(ddl)
SBO: SBO_0080(ddl) SBO_0276(ddl)
SBC: SbBS512_E0085(ddl) SbBS512_E0298(ddl)
SDY: SDY_0122(ddl) SDY_0365(ddl)
ECA: ECA3813(ddl)
PCT: PC1_3590
PWA: Pecwa_3778
ETA: ETA_07570(ddl)
PLU: plu3652(ddl)
PAY: PAU_01115(ddlB)
BAS: BUsg208(ddl)
BAB: bbp196(ddl)
WBR: WGLp217(ddlA)
SGL: SG0899
ENT: Ent638_0638(ddl) Ent638_0850(ddl)
ESA: ESA_02926 ESA_03246(ddl)
CTU: Ctu_07250(ddlB) Ctu_09540(ddlA)
KPN: KPN_00096(ddl) KPN_00323(ddl)
KPE: KPK_4364(ddlA) KPK_4645(ddl)
KPU: KP1_0914(ddl) KP1_1182(ddl)
CKO: CKO_02797(ddl) CKO_03283(ddl)
SPE: Spro_0763(ddl) Spro_1367
PMR: PMI1243(ddlA)
EIC: NT01EI_0738 NT01EI_3744
ETR: ETAE_0639(ddl) ETAE_3371
BFL: Bfl474(ddl)
BPN: BPEN_490(ddl)
HDE: HDEF_1781(ddlB)
DDA: Dd703_3243
DDC: Dd586_0704
DZE: Dd1591_3345
HIN: HI1140(ddl)
HIT: NTHI1308(ddl)
HIP: CGSHiEE_06350(ddl)
HIQ: CGSHiGG_09360(ddl)
HDU: HD0821(ddl)
HAP: HAPS_0121(ddl)
HSO: HS_0360(ddl)
HSM: HSM_0630(ddl)
PMU: PM0144(ddl)
MSU: MS1664(ddl)
APL: APL_0020(ddl)
APJ: APJL_0021(ddl)
APA: APP7_0020(ddl)
ASU: Asuc_1930(ddl)
AAP: NT05HA_0220
AAT: D11S_0788
XFA: XF0799(ddl)
XFT: PD1864(ddl)
XFM: Xfasm12_2046(ddl)
XFN: XfasM23_1967(ddl)
XCC: XCC0222(ddl) XCC0727(ddl)
XCB: XC_0232(ddl) XC_3508(ddl)
XCA: xccb100_0244(ddl) xccb100_3629(ddl)
XCV: XCV0246(ddl) XCV0832(ddl)
XAC: XAC0781(ddl)
XOO: XOO0352(ddl) XOO3824(ddl)
XOM: XOO_0324(ddl) XOO_3602(ddl)
XOP: PXO_02772(ddl) PXO_04365(ddl)
SML: Smlt0211(ddl) Smlt0757(ddl)
SMT: Smal_0173(ddl) Smal_0604(ddl)
VCH: VCA0572(ddl)
VCO: VC0395_0515(ddl)
VCM: VCM66_A0531(ddlA)
VCJ: VCD_000746
VVU: VV2_0280(ddl)
VVY: VVA0785(ddl)
VPA: VPA0886(ddl)
VHA: VIBHAR_05785(ddl)
VSP: VS_II0746(ddl)
VEX: VEA_000154
VFI: VF_A0570(ddl)
VFM: VFMJ11_A0584(ddl)
VSA: VSAL_II0639(ddl)
PPR: PBPRA1964 PBPRB0927(ddl)
PAE: PA4201(ddlA) PA4410(ddl)
PAU: PA14_09600(ddlA) PA14_57320(ddl)
PAP: PSPA7_0897(ddlA) PSPA7_4982(ddl)
PAG: PLES_07261(ddlA) PLES_47891(ddl)
PPU: PP_1339(ddl) PP_4346(ddlA)
PPF: Pput_1516 Pput_1521 Pput_4385(ddl)
PPG: PputGB1_4510(ddl)
PPW: PputW619_0946(ddl) PputW619_3672 PputW619_3677
PST: PSPTO_4182 PSPTO_4406
PSB: Psyr_3919(ddl) Psyr_4100(ddl)
PSP: PSPPH_3913(ddl) PSPPH_4106(ddl)
PFL: PFL_5059(ddl) PFL_5194(ddl)
PFO: Pfl01_4671(ddl)
PFS: PFLU0706(ddlA) PFLU0949(ddlB)
PEN: PSEEN4483(ddl)
PMY: Pmen_0924(ddl)
PSA: PST_1084(ddl)
CJA: CJA_2927
AVN: Avin_13270(ddl)
PAR: Psyc_1749(ddl)
PCR: Pcryo_2030(ddl)
PRW: PsycPRwf_0526(ddl)
ACI: ACIAD3515(ddl)
ACB: A1S_3334(ddl)
ABM: ABSDF3470(ddl)
ABY: ABAYE0150(ddl)
ABC: ACICU_03532(ddl)
ABN: AB57_3785(ddl)
ABB: ABBFA_000147(ddl)
SON: SO_2217(ddl)
SDN: Sden_2354(ddl)
SFR: Sfri_2550(ddl)
SAZ: Sama_1903(ddl)
SBL: Sbal_2283(ddl) Sbal_4569(ddl)
SBM: Shew185_2043(ddl)
SBN: Sbal195_2090(ddl)
SBP: Sbal223_2294(ddl)
SLO: Shew_2133(ddl)
SPC: Sputcn32_1801(ddl)
SSE: Ssed_1920(ddl)
SPL: Spea_2422(ddl)
SHE: Shewmr4_2129(ddl)
SHM: Shewmr7_2205(ddl)
SHN: Shewana3_2307(ddl)
SHW: Sputw3181_2224(ddl)
SHL: Shal_1854(ddl)
SWD: Swoo_2674(ddl)
SWP: swp_2771(ddl)
ILO: IL0438(ddl)
CPS: CPS_4463
PHA: PSHAa2502(ddlB)
PAT: Patl_3517(ddl)
SDE: Sde_0850
MAQ: Maqu_2450
AMC: MADE_03256(ddl)
PIN: Ping_0036 Ping_1149
TTU: TERTU_3047
CBU: CBU_1338(ddl)
CBS: COXBURSA331_A1490(ddl)
CBD: CBUD_1427(ddl)
CBG: CbuG_0670(ddl)
CBC: CbuK_1202(ddl)
LPN: lpg2612(ddl)
LPF: lpl2535(ddl)
LPP: lpp2665(ddl)
LPC: LPC_0529(ddl)
MCA: MCA2426(ddl)
FTU: FTT_0185(ddlB)
FTF: FTF0185(ddlB)
FTW: FTW_1906
FTL: FTL_1910
FTH: FTH_1509(ddlA) FTH_1833(ddlB)
FTA: FTA_2017
FTN: FTN_0161(ddlB)
FPH: Fphi_0663
TCX: Tcr_0585
NOC: Noc_2858
AEH: Mlg_2190(ddl)
HHA: Hhal_1501 Hhal_2088(ddl)
TGR: Tgr7_0772
HNA: Hneap_0452
HCH: HCH_05881 HCH_06188
CSA: Csal_2188
ABO: ABO_0600(ddl)
MMW: Mmwyl1_2612
AHA: AHA_2404(ddl)
ASA: ASA_2261(ddl)
TAU: Tola_0232
DNO: DNO_0979
AFE: Lferr_0382
AFR: AFE_0203(ddlB)
BCI: BCI_0388(ddlA)
RMA: Rmag_0759
VOK: COSY_0701(ddlB)
KKO: Kkor_0691
NMA: NMA2060(ddl)
NME: NMB0424(ddl)
NMC: NMC1740(ddl)
NMN: NMCC_1720(ddl)
NMI: NMO_1616(ddlB)
NGO: NGO1531(ddl)
NGK: NGK_1820(ddl)
CVI: CV_2472(ddl) CV_4341(ddl)
LHK: LHK_03053(ddlB)
RSO: RSc2842(ddl)
RPI: Rpic_3087(ddl)
RPF: Rpic12D_2722
REU: Reut_A2977(ddl)
REH: H16_A3271(ddl)
RME: Rmet_3126(ddl)
CTI: RALTA_A2727(ddl)
BMA: BMA2549(ddl)
BMV: BMASAVP1_A0470(ddl)
BML: BMA10229_A1329(ddl)
BMN: BMA10247_3234(ddl)
BPS: BPSL3023(ddl)
BPM: BURPS1710b_3542(ddl)
BPL: BURPS1106A_3548(ddl)
BPD: BURPS668_3523(ddl)
BPR: GBP346_A3696
BTE: BTH_I1120(ddl)
BVI: Bcep1808_0537(ddl)
BUR: Bcep18194_A3647(ddl) Bcep18194_C6870
BCN: Bcen_0079(ddl)
BCH: Bcen2424_0561(ddl)
BCM: Bcenmc03_0532(ddl)
BCJ: BCAL3460(ddl)
BAM: Bamb_0465(ddl)
BAC: BamMC406_0490(ddl)
BMU: Bmul_2834(ddl)
BMJ: BMULJ_00404(ddl)
BXE: Bxe_A0488(ddl)
BPH: Bphy_2671(ddl)
BPY: Bphyt_3468(ddl)
BGL: bglu_1g04640
PNU: Pnuc_0169(ddl)
PNE: Pnec_0183(ddl)
BPE: BP3021(ddl)
BPA: BPP3750(ddl)
BBR: BB4196(ddl)
BPT: Bpet0699(ddl)
BAV: BAV2877(ddl)
RFR: Rfer_3423
POL: Bpro_1077(ddl)
PNA: Pnap_3415(ddl)
AAV: Aave_0823(ddl)
AJS: Ajs_3668(ddl)
VEI: Veis_4572(ddl)
DAC: Daci_1472(ddl)
DIA: Dtpsy_2978
VAP: Vapar_0921
CTT: CtCNB1_4112
MPT: Mpe_A0464(ddl)
HAR: HEAR2809(ddl)
MMS: mma_3013(ddl)
LCH: Lcho_0524(ddl)
NEU: NE0994(ddl)
NET: Neut_0243(ddl)
NMU: Nmul_A2491(ddl)
EBA: ebA1442(ddl)
AZO: azo0886(ddl)
DAR: Daro_3496(ddl)
TBD: Tbd_0122(ddl)
MFA: Mfla_2266(ddl)
MMB: Mmol_2001
MEI: Msip34_0463
APP: CAP2UW1_0569
HPY: HP0738(ddl)
HPJ: jhp0675(ddl)
HPA: HPAG1_0722(ddl)
HPS: HPSH_03150(ddl)
HPG: HPG27_694(ddl)
HPP: HPP12_0747(ddl)
HPB: HELPY_0629(ddlA)
HHE: HH0131(ddl)
HAC: Hac_0681(ddl)
WSU: WS0438(ddl)
TDN: Suden_1208(ddl)
CJE: Cj0798c(ddl)
CJR: CJE0889(ddl)
CJJ: CJJ81176_0819(ddl)
CJU: C8J_0749(ddl)
CJD: JJD26997_1212(ddl)
CFF: CFF8240_0808(ddl)
CCV: CCV52592_1152(ddl)
CHA: CHAB381_0572(ddl)
CLA: Cla_0634(ddlA)
ABU: Abu_0745(ddl)
SDL: Sdel_1050
NIS: NIS_1097(ddl)
SUN: SUN_0177(ddl)
NAM: NAMH_0945
GSU: GSU3066(ddl)
GME: Gmet_0415
GUR: Gura_3971
GLO: Glov_0667
GBM: Gbem_0494
GEO: Geob_0783
GEM: GM21_0511
PCA: Pcar_2199
PPD: Ppro_3286
DVU: DVU0334
DVL: Dvul_2649
DVM: DvMF_1246
DDE: Dde_0366 Dde_3042 Dde_3043
DDS: Ddes_0872
DMA: DMR_20330(ddl)
DSA: Desal_0981
LIP: LI0682(ddlA)
DBA: Dbac_0136 Dbac_1774 Dbac_1775
DRT: Dret_1074
BBA: Bd0585(ddlA)
DPS: DP0058
DOL: Dole_1426 Dole_2749
DAL: Dalk_3244
DAT: HRM2_09290(ddlA) HRM2_13230(ddlB1) HRM2_13240(ddlB2)
ADE: Adeh_2449 Adeh_3774
ACP: A2cp1_1506 A2cp1_3914
AFW: Anae109_1418 Anae109_3887
ANK: AnaeK_1410 AnaeK_3830
MXA: MXAN_4097 MXAN_5601 MXAN_5741
SCL: sce0564(ddlA1) sce2763 sce6856(ddlB)
HOH: Hoch_0360 Hoch_4160
SAT: SYN_00412 SYN_01483
SFU: Sfum_0712 Sfum_0713 Sfum_4102
RPR: RP249(ddl)
RTY: RT0241(ddl)
RCM: A1E_01430(ddl)
RCO: RC0333(ddl)
RFE: RF_1035(ddl)
RAK: A1C_01810(ddl)
RRI: A1G_01910(ddl)
RRJ: RrIowa_0403(ddl)
RMS: RMA_0341(ddl)
RPK: RPR_02150(ddl)
RAF: RAF_ORF0310(ddlB)
RBE: RBE_0961(ddl)
RBO: A1I_03850(ddl)
OTS: OTBS_0598(ddl)
OTT: OTT_0949(ddl)
WOL: WD0095
WBM: Wbm0570
WRI: WRi_001550
WPI: WPa_0403
AMA: AM205(ddlB)
AMF: AMF_151(ddlB)
ACN: ACIS_01079(ddlB)
PUB: SAR11_0021(ddlB)
MLO: mll1551(ddl) mll1812
MES: Meso_2004(ddl)
PLA: Plav_2424
SME: SMc01871(ddl)
SMD: Smed_2077(ddl)
ATU: Atu2089(ddl)
ATC: AGR_C_3788
ARA: Arad_1819(ddlA) Arad_2991(ddlB)
AVI: Avi_2887(ddl)
RET: RHE_CH02464(ddlA) RHE_CH02843(ddl)
REC: RHECIAT_CH0002567(ddlA) RHECIAT_CH0002994(ddl)
RLE: RL2801(ddlA) RL3301(ddl)
RLT: Rleg2_2101 Rleg2_2589(ddl)
RLG: Rleg_2342 Rleg_2848
RHI: NGR_a01660 NGR_c21040(ddlB)
LAS: CLIBASIA_05430(ddl)
BME: BMEI0582(ddl) BMEI0727
BMF: BAB1_1291 BAB1_1447(ddl)
BMB: BruAb1_1273(ddlA) BruAb1_1423(ddl)
BMC: BAbS19_I12040 BAbS19_I13530(ddl)
BMS: BR1271(ddlA) BR1428(ddl)
BMT: BSUIS_A1320 BSUIS_A1480(ddl)
BOV: BOV_1232(ddlA) BOV_1385(ddl)
BCS: BCAN_A1292 BCAN_A1461(ddl)
BMR: BMI_I1282(ddlA) BMI_I1440(ddl)
OAN: Oant_1747(ddl)
BJA: bll6599 blr3405(ddl) blr6438(ddlA)
BRA: BRADO2810(ddl) BRADO5656(ddlB)
BBT: BBta_5374(ddl) BBta_6169(ddlB)
RPA: RPA3525(ddlA)
RPB: RPB_2001
RPC: RPC_3301(ddl)
RPD: RPD_3389
RPE: RPE_2113(ddl)
RPT: Rpal_4043
NWI: Nwi_1055
NHA: Nham_1283
OCA: OCAR_5247(ddl)
BHE: BH11210(ddl)
BQU: BQ08830(ddl)
BBK: BARBAKC583_0944(ddl)
BTR: Btr_1588(ddl)
BGR: Bgr_13940(ddlB)
XAU: Xaut_0325(ddl)
AZC: AZC_4561
MEX: Mext_2946(ddl)
MEA: Mex_1p3151(ddlB)
MDI: METDI3716(ddlB)
MRD: Mrad2831_2353(ddl)
MET: M446_0922(ddl)
MPO: Mpop_3130(ddl)
MCH: Mchl_3173(ddl)
MNO: Mnod_1308 Mnod_7439
BID: Bind_0695
MSL: Msil_3492
CCR: CC_2543(ddl)
CCS: CCNA_02626
CAK: Caul_3404 Caul_3660(ddl)
PZU: PHZ_c2317(ddl)
SIL: SPO1201(ddl)
SIT: TM1040_0686(ddl)
RSP: RSP_2111(ddl)
RSH: Rsph17029_0787(ddl)
RSQ: Rsph17025_0697(ddl)
RSK: RSKD131_0421
JAN: Jann_2753(ddl)
RDE: RD1_3351(ddl)
PDE: Pden_1204 Pden_2406 Pden_4490(ddl)
DSH: Dshi_2419(ddl)
MMR: Mmar10_2074
HNE: HNE_0393
HBA: Hbal_0403
ZMO: ZMO0834
ZMN: Za10_0454
NAR: Saro_1136
SAL: Sala_1878
SWI: Swit_2496 Swit_3943
ELI: ELI_01810
GOX: GOX0161(ddl)
GBE: GbCGDNIH1_0426(ddl)
ACR: Acry_0066(ddl)
GDI: GDI_3193(murB)
GDJ: Gdia_3167(ddl)
APT: APA01_19020
RRU: Rru_A0947
RCE: RC1_0609(ddlB)
MAG: amb3851
MGM: Mmc1_0750
BSU: BSU04560(ddl)
BHA: BH1621(ddlA)
BAN: BA2610(ddl)
BAR: GBAA2610(ddl)
BAA: BA_0812
BAT: BAS0230 BAS2435(ddl)
BAH: BAMEG_0273 BAMEG_1985(ddlB)
BAI: BAA_0272 BAA_2673(ddlB)
BCE: BC0257(ddl) BC2550(ddl)
BCA: BCE_0265(ddl) BCE_2628(ddl)
BCZ: BCZK0219(ddl) BCZK2356(ddl)
BCR: BCAH187_A0279(ddl) BCAH187_A2666(ddl)
BCB: BCB4264_A0260(ddl) BCB4264_A2582(ddl)
BCU: BCAH820_0257(ddl) BCAH820_2627(ddl)
BCG: BCG9842_B2741(ddl) BCG9842_B5065(ddl)
BCQ: BCQ_0261(ddlA) BCQ_2484(ddlB)
BCX: BCA_0282 BCA_2700(ddlB)
BCY: Bcer98_0232(ddl)
BTK: BT9727_0217(ddl) BT9727_2390(ddl)
BTL: BALH_0230(ddl) BALH_2350(ddl)
BWE: BcerKBAB4_0223(ddl) BcerKBAB4_2524(ddl)
BLI: BL02193(ddl)
BLD: BLi00543(ddl)
BCL: ABC2907(ddl)
BAY: RBAM_004900(ddl)
BPU: BPUM_0427(ddl)
OIH: OB1306(ddl)
GKA: GK0223(ddl)
GTN: GTNG_0198(ddl)
GWC: GWCH70_0203
GYM: GYMC10_0868 GYMC10_4662
GYC: GYMC61_1084
AFL: Aflv_0192(ddl)
SAU: SA1887(ddl)
SAV: SAV2083(ddl)
SAW: SAHV_2068(ddl)
SAM: MW2006(ddl)
SAR: SAR2170(ddl)
SAS: SAS1987(ddl)
SAC: SACOL2074(ddl)
SAB: SAB1967c(ddl)
SAA: SAUSA300_2039(ddl)
SAX: USA300HOU_2078(ddl)
SAO: SAOUHSC_02318(ddl)
SAJ: SaurJH9_2120(ddl)
SAH: SaurJH1_2158(ddl)
SAE: NWMN_1987(ddl)
SAD: SAAV_2137(ddl)
SEP: SE1681(ddl)
SER: SERP1690(ddl)
SHA: SH0954(ddl)
SSP: SSP0800(ddl)
SCA: Sca_1583(ddlA)
LMO: lmo0855(ddl)
LMF: LMOf2365_0872(ddl)
LMH: LMHCC_1773(ddl)
LMC: Lm4b_00871(ddlA)
LIN: lin0848(ddl)
LWE: lwe0848(ddl)
LSP: Bsph_4313 Bsph_4528(ddl)
ESI: Exig_1814
EAT: EAT1b_2979
MCL: MCCL_1741(ddl)
BBE: BBR47_05870 BBR47_20440(ddl) BBR47_28450(ddl)
PJD: Pjdr2_0813 Pjdr2_5375 Pjdr2_5609
AAC: Aaci_1636
LLA: L140690(ddl)
LLK: LLKF_0396(ddl)
LLC: LACR_0387(ddl)
LLM: llmg_0360(ddl)
SPY: SPy_1421(ddl)
SPZ: M5005_Spy_1158(ddl)
SPM: spyM18_1431(ddl)
SPG: SpyM3_1084(ddl)
SPS: SPs0780(ddl)
SPH: MGAS10270_Spy1229(ddl)
SPI: MGAS10750_Spy1266(ddl)
SPJ: MGAS2096_Spy1229(ddl)
SPK: MGAS9429_Spy1205(ddl)
SPF: SpyM50702(ddl)
SPA: M6_Spy1185(ddl)
SPB: M28_Spy1152(ddl)
SOZ: Spy49_1137c(ddl)
SPN: SP_1671(ddl)
SPD: SPD_1484(ddl)
SPR: spr1515(ddl)
SPW: SPCG_1643(ddl)
SPX: SPG_1580(ddl)
SNE: SPN23F_16720(ddlA)
SPV: SPH_1779(ddl)
SNM: SP70585_1137 SP70585_1711
SJJ: SPJ_1566
SPP: SPP_1689
SNT: SPT_1610
SAG: SAG0767(ddl)
SAN: gbs0787(ddl)
SAK: SAK_0892(ddl)
SMU: SMU.599(ddl)
STC: str1583(ddl)
STL: stu1583(ddl)
STE: STER_1544(ddl)
SSA: SSA_0691(ddl)
SSU: SSU05_1352
SSV: SSU98_1367
SSB: SSUBM407_0477 SSUBM407_0605(ddlA)
SSI: SSU1184(ddlA)
SSS: SSUSC84_1217(ddlA)
SGO: SGO_1447(ddl)
SEQ: SZO_13560
SEZ: Sez_0642(ddl)
SEU: SEQ_0662
SUB: SUB1257(ddlA)
SDS: SDEG_1463(ddl)
LPL: lp_2345(ddl)
LPJ: JDM1_1961(ddl)
LJO: LJ0108(ddl)
LJF: FI9785_175(ddlA)
LAC: LBA0137(ddl)
LSA: LSA0049(ddl)
LSL: LSL_1083(ddl)
LDB: Ldb0185(ddl)
LBU: LBUL_0161(ddl)
LBR: LVIS_1268(ddl)
LCA: LSEI_0143
LCB: LCABL_01350(ddl)
LGA: LGAS_0107(ddl)
LRE: Lreu_0477(ddl)
LRF: LAR_0465(ddl)
LHE: lhv_0143(ddl)
LFE: LAF_0451(ddl)
LRH: LGG_00148(ddl2)
LRL: LC705_00147(ddl)
EFA: EF0843 EF2294(vanB)
OOE: OEOE_0672(ddl)
LME: LEUM_0264(ddl)
LCI: LCK_00212(ddl)
CAC: CAC2895(ddl)
CPE: CPE0819(ddl) CPE1315(ddl)
CPF: CPF_0816(ddl) CPF_1522(ddl)
CPR: CPR_1312(ddl)
CTC: CTC00291(ddl) CTC00683(ddl)
CNO: NT01CX_0559(ddl)
CTH: Cthe_1938
CDF: CD1408(ddl) CD1626(vanG)
CDC: CD196_1278(ddl) CD196_1549(vanG)
CDL: CDR20291_1255(ddl) CDR20291_1524(vanG)
CBO: CBO0452(ddl)
CBA: CLB_0493(ddl)
CBH: CLC_0526(ddl)
CBY: CLM_0535(ddlB)
CBL: CLK_3656(ddl)
CBK: CLL_A3075(ddl)
CBB: CLD_0290(ddl)
CBI: CLJ_B0526(ddlB)
CBT: CLH_2823(ddl)
CBF: CLI_0538(ddl)
CBE: Cbei_0581(ddl)
CKL: CKL_2914(ddl)
CKR: CKR_2584
CPY: Cphy_0084 Cphy_1644 Cphy_3791
CCE: Ccel_0283
AMT: Amet_2954 Amet_3710 Amet_4591
AOE: Clos_0292 Clos_2860
STH: STH512
SWO: Swol_1155
VPR: Vpar_1111
ATE: Athe_2039
DSY: DSY1579(ddl) DSY3690
DHD: Dhaf_1664 Dhaf_2721
DRM: Dred_1796
DAE: Dtox_2148
PTH: PTH_1390(ddlA)
DAU: Daud_1240
HMO: HM1_2570(ddl)
FMA: FMG_0263
APR: Apre_0437
EEL: EUBELI_00604
ERE: EUBREC_2678 EUBREC_2937
TTE: TTE2545(ddlA2)
TEX: Teth514_0610(ddl) Teth514_1784
TPD: Teth39_0187(ddl) Teth39_2176
CHY: CHY_1346(ddl)
MTA: Moth_1140
ADG: Adeg_1108
CSC: Csac_1372
CPO: COPRO5265_0677
NTH: Nther_0011
HOR: Hore_08980
MTU: Rv2981c(ddl)
MTC: MT3059(ddl)
MRA: MRA_3010(ddl)
MTF: TBFG_12996(ddl)
MTB: TBMG_00988(TBMG_00988.1)
MBO: Mb3005c(ddl)
MBB: BCG_3002c(ddl)
MBT: JTY_2997(ddl)
MLE: ML1678(ddl)
MLB: MLBr_01678(ddlA)
MPA: MAP3019c(ddl)
MAV: MAV_3830(ddl)
MSM: MSMEG_2395(ddl)
MUL: MUL_1976(ddl)
MVA: Mvan_2143(ddl)
MGI: Mflv_4219(ddl)
MAB: MAB_3286c(ddl)
MMC: Mmcs_1929(ddl)
MKM: Mkms_1975(ddl)
MJL: Mjls_1909(ddl)
MMI: MMAR_1733(ddl)
CGL: NCgl1267(ddl)
CGB: cg1493(ddl)
CGT: cgR_1395(ddl)
CEF: CE1431(ddl)
CDI: DIP1131(ddl)
CJK: jk0921(ddlA1-N) jk0922(ddlA1-C) jk1217(ddl)
CUR: cur_0778(ddl)
CAR: cauri_1160(ddlA)
CKP: ckrop_1208(ddlA)
NFA: nfa42050(ddl)
RHA: RHA1_ro06507(ddl)
RER: RER_24160(ddl)
ROP: ROP_65580(ddl)
GBR: Gbro_0407
SCO: SCO3595(ddlA2) SCO5560(ddl)
SMA: SAV_2679(ddl)
SGR: SGR_1921(ddl)
TWH: TWT505(ddlA)
TWS: TW257(ddlA)
LXX: Lxx09710(ddlA)
CMI: CMM_0263(ddlA) CMM_1346(ddlC) CMM_2970(ddlB)
CMS: CMS_0834 CMS_2047(ddl) CMS_3106(ddlB)
ART: Arth_2514(ddl)
AAU: AAur_2481(ddl)
ACH: Achl_2251
RSA: RSal33209_0873
KRH: KRH_10370(ddl)
MLU: Mlut_08790
BCV: Bcav_1595 Bcav_4215
BFA: Bfae_18500
JDE: Jden_1680 Jden_2550
KSE: Ksed_10770
XCE: Xcel_2285 Xcel_3371
PAC: PPA1359 PPA2338
NCA: Noca_3291 Noca_3486 Noca_4691
TFU: Tfu_0633(ddl) Tfu_1640
TCU: Tcur_3455 Tcur_4976
SRO: Sros_8008 Sros_9380
FRA: Francci3_3609(ddl)
FRE: Franean1_1130(ddl) Franean1_6711 Franean1_7137
FAL: FRAAL3074(ddlA) FRAAL5814(ddl)
ACE: Acel_1586 Acel_2153
NML: Namu_1485 Namu_5406
KRA: Krad_1363
SEN: SACE_6130(ddl) SACE_7389(ddlA)
SVI: Svir_09160 Svir_39720
AMI: Amir_4256 Amir_5988 Amir_7091
STP: Strop_1272 Strop_4584
SAQ: Sare_1162 Sare_5102
CAI: Caci_5793 Caci_8041 Caci_9048
BLO: BL0345(ddl)
BLJ: BLD_1112(ddl)
BLN: Blon_0320(ddl)
BAD: BAD_0186(ddl)
BLA: BLA_0236(ddlA)
BLC: Balac_0248
BLT: Balat_0248
RXY: Rxyl_2329 Rxyl_2952
AFO: Afer_0599
CCU: Ccur_03490 Ccur_14120
SHI: Shel_28460
APV: Apar_0319 Apar_1360
ELE: Elen_3114
CTR: CT762(murC)
CTA: CTA_0832(murC-ddlA)
CTB: CTL0131(murC)
CTL: CTLon_0131(murC)
CTJ: JALI_7671(murC)
CMU: TC0143(murC)
CPN: CPn0905(murC)
CPA: CP0961
CPJ: CPj0905(murC_ddlA)
CPT: CpB0937
CCA: CCA00863(murC)
CAB: CAB829
CFE: CF0153(mudD)
BBZ: BbuZS7_0201
BGA: BG0199(ddlA)
BAF: BAPKO_0203(ddlA)
BTU: BT0200
BHR: BH0200
BDU: BDU_198(ddlA)
BRE: BRE_197(ddlA)
TPP: TPASS_0670(ddlA)
TDE: TDE2385
LIL: LA2058 LA2699
LIC: LIC11304(ddl) LIC11855(ddlA)
LBJ: LBJ_1946(ddlA) LBJ_2005
LBL: LBL_1045 LBL_1338(ddlA)
LBI: LEPBI_I1796 LEPBI_I1863(ddlB)
LBF: LBF_1743 LBF_1808(ddlA)
BHY: BHWA1_01871(ddl)
ABA: Acid345_1551 Acid345_4592
ACA: ACP_2209
SUS: Acid_2799
BTH: BT_3713(ddl)
BFR: BF0490(ddl)
BFS: BF0435(ddl)
BVU: BVU_0547(ddl)
PGI: PG0729(ddl)
PGN: PGN_0760(ddl)
PDI: BDI_2675(ddl)
APS: CFPG_116(ddl)
SRU: SRU_2197
RMR: Rmar_0135 Rmar_0998
CHU: CHU_0924(ddlA)
DFE: Dfer_4937
CPI: Cpin_5946
PHE: Phep_1847
GFO: GFO_2684(ddl)
FJO: Fjoh_2618(ddl)
FPS: FP0653(ddl)
FBA: FIC_02185
COC: Coch_1370
RBI: RB2501_02270
BBL: BLBBGE_126(ddlA)
BPI: BPLAN_509(ddl)
AAS: Aasi_0291 Aasi_1367
FSU: Fisuc_0053
FNU: FN1454
LBA: Lebu_1771
STR: Sterm_0260
SMF: Smon_1078
OTE: Oter_2162 Oter_2638
MIN: Minf_1408(ddlA)
AMU: Amuc_0661 Amuc_0730
GAU: GAU_3895(ddl)
RBA: RB13271(ddlA)
EMI: Emin_1090
RSD: TGRD_636
TAI: Taci_1244
SYN: slr1874(ddl)
SYW: SYNW1641(ddl)
SYC: syc1730_c(ddl)
SYF: Synpcc7942_2375(ddl)
SYD: Syncc9605_0849(ddl)
SYE: Syncc9902_1541(ddl)
SYG: sync_0734(ddl)
SYR: SynRCC307_0603(ddl)
SYX: SynWH7803_1756(ddl)
SYP: SYNPCC7002_A1584(ddl)
CYA: CYA_0110(ddlB)
CYB: CYB_2109(ddlB)
TEL: tll0523(ddl)
MAR: MAE_24510(ddl)
CYT: cce_3118 cce_4735(ddl)
CYP: PCC8801_3354(ddl)
CYC: PCC7424_0104(ddl)
CYN: Cyan7425_1199
CYH: Cyan8802_2763
GVI: gll0297
ANA: all0980(ddl)
NPU: Npun_F5597 Npun_R6628(ddl)
AVA: Ava_0360(ddl)
PMA: Pro1380(ddlA)
PMM: PMM1306(ddl)
PMT: PMT0322(ddl)
PMN: PMN2A_0872
PMI: PMT9312_1402(ddl)
PMB: A9601_15051(ddl)
PMC: P9515_14671(ddl)
PMF: P9303_19931(ddl)
PMG: P9301_14921(ddl)
PMH: P9215_15351(ddl)
PMJ: P9211_13541
PME: NATL1_17261(ddlA)
TER: Tery_2970 Tery_2971 Tery_4217(ddl)
AMR: AM1_2595(ddl) AM1_3124(ddl)
CTE: CT1345(ddl)
CPC: Cpar_0811(ddl)
CCH: Cag_0905(ddl)
CPH: Cpha266_1662(ddl)
CPB: Cphamn1_1004(ddl)
CLI: Clim_1529(ddl)
PVI: Cvib_0722(ddl)
PLT: Plut_1331(ddl)
PPH: Ppha_1631(ddl)
PAA: Paes_1480(ddl)
CTS: Ctha_0351 Ctha_1122
DET: DET0629
DEH: cbdb_A616(ddl)
DEB: DehaBAV1_0602
DEV: DhcVS_570(ddlA)
RRS: RoseRS_3791
RCA: Rcas_1090
CAU: Caur_0751
CAG: Cagg_2856
CHL: Chy400_0814
HAU: Haur_3506
TRO: trd_0065
STI: Sthe_1990
DRA: DR_0362(ddl)
DGE: Dgeo_2121(ddl)
DDR: Deide_19100
TTH: TTC1223
TTJ: TTHA1587
AAE: aq_521(ddlA)
HYA: HY04AAS1_0137
SUL: SYO3AOP1_0420
SAF: SULAZ_1192
PMX: PERMA_0620 PERMA_1252
TMA: TM0259
TPT: Tpet_0358 Tpet_0665
TLE: Tlet_0834 Tlet_0898 Tlet_1858
TRQ: TRQ2_0689
TNA: CTN_0105 CTN_0427
TNP: Tnap_0342 Tnap_0889
TME: Tmel_0081 Tmel_0486
TAF: THA_298 THA_792
FNO: Fnod_1588
PMO: Pmob_1643
KOL: Kole_0926 Kole_1656
DTH: DICTH_0803
DTU: Dtur_0952
TYE: THEYE_A1319
TTR: Tter_1603
MEM: Memar_0655
Taxonomy
Structures PDB: 1EHI  1IOV  1IOW  2DLN  2FB9  2I80  2I87  2I8C  2PVP  2YZG  
     2YZM  2YZN  2ZDG  2ZDH  2ZDQ  3I12  
Reference
  Authors
  Title

  Journal
 1
Ito, E. and Strominger, J.L.
Enzymatic synthesis of the peptide in bacterial uridine nucleotides.
II. Enzymatic synthesis and addition of D-alanyl-D-alanine.
J. Biol. Chem. 237 (1962) 2696-2703.
Reference
  Authors
  Title
  Journal
 2
Neuhaus, F.C.
Kinetic studies on D-Ala-D-Ala synthetase.
Fed. Proc. 21 (1962) 229.
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:11699883]
van Heijenoort J.
Recent advances in the formation of the bacterial peptidoglycan
monomer unit.
Nat. Prod. Rep. 18 (2001) 503-19.
Staphylococcus aureus
Other DBs ExplorEnz - The Enzyme Database: 6.3.2.4
IUBMB Enzyme Nomenclature: 6.3.2.4
ExPASy - ENZYME nomenclature database: 6.3.2.4
BRENDA, the Enzyme Database: 6.3.2.4
CAS: 9023-63-6
DBGET integrated database retrieval system