| Entry |
|
|---|
| Name |
GMP synthase;
xanthosine-5'-phosphate---ammonia ligase;
guanylate synthetase;
XMP aminase;
xanthosine 5'-monophosphate aminase |
|---|
| Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
 |
|---|
| Sysname |
xanthosine-5'-phosphate:ammonia ligase (AMP-forming) |
|---|
| Reaction(IUBMB) |
ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP
[RN:R01230] |
|---|
| Reaction(KEGG) |
R01230
 |
|---|
| Substrate |
ATP [CPD:C00002];
xanthosine 5'-phosphate [CPD:C00655];
NH3 [CPD:C00014] |
|---|
| Product |
AMP [CPD:C00020];
diphosphate [CPD:C00013];
GMP [CPD:C00144] |
|---|
| Pathway |
PATH: ec00230 Purine metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K01936 GMP synthase |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13428768]
MOYED HS, MAGASANIK B.
Enzymes essential for the biosynthesis of nucleic acid guanine;
xanthosine 5'-phosphate aminase of Aerobacter aerogenes.
J. Biol. Chem. 226 (1957) 351-63.
Aerobacter aerogenes |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 6.3.4.1
IUBMB Enzyme Nomenclature: 6.3.4.1
ExPASy - ENZYME nomenclature database: 6.3.4.1
BRENDA, the Enzyme Database: 6.3.4.1
CAS: 9023-55-6 |
|---|
