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Entry
EC 6.3.4.10                 Enzyme                                 
Name biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase;
biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] synthetase;
biotin-propionyl coenzyme A carboxylase synthetase;
propionyl coenzyme A holocarboxylase synthetase
Class Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
BRITE hierarchy
Sysname biotin:apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
ligase (AMP-forming)
Reaction(IUBMB) ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase
(ADP-forming)] = AMP + diphosphate + [propionyl-CoA:carbon-dioxide
ligase (ADP-forming)] [RN:R04582]
Reaction(KEGG) R04582;
(other) R01074 R05145
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Substrate ATP [CPD:C00002];
biotin [CPD:C00120];
apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD:C04763]
Product AMP [CPD:C00020];
diphosphate [CPD:C00013];
[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD:C04727]
Pathway PATH: ec00780  Biotin metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K01942  biotin--protein ligase
Genes HSA: 3141(HLCS)
PTR: 473989(HLCS)
MCC: 694733(HLCS)
MMU: 110948(Hlcs)
RNO: 288240(Hlcs)
CFA: 478412(HLCS)
BTA: 534247(HLCS)
ECB: 100061132
MDO: 100012694
OAA: 100087267
GGA: 418516(HLCS)
TGU: 100229815
DRE: 337784(hlcs)
CIN: 100179742
DME: Dmel_CG14670(Hcs)
DPO: Dpse_GA26365
DAN: Dana_GF17255
DER: Dere_GG12849
DPE: Dper_GL21666
DSE: Dsec_GM10811
DSI: Dsim_GD19789
DYA: Dyak_GE25471
DGR: Dgri_GH18598
DMO: Dmoj_GI23080
AGA: AgaP_AGAP001481
AAG: AaeL_AAEL009340
CQU: CpipJ_CPIJ007072
AME: 411759
NVI: 100120765
TCA: 100141937
API: 100166501
ISC: IscW_ISCW015948
BMY: Bm1_15240
SMM: Smp_153150
NVE: NEMVE_v1g105387
TAD: TRIADDRAFT_31020
POP: POPTR_818510
PPP: PHYPADRAFT_143161
CRE: CHLREDRAFT_169728
SCE: YDL141W(BPL1)
AGO: AGOS_ADR085W
KLA: KLLA0F05049g
LTH: KLTH0H02024g
DHA: DEHA0A14168g
PIC: PICST_69676(BPL1)
PPA: PAS_chr3_0569
VPO: Kpol_1019p23
LEL: LELG_05238
ZRO: ZYRO0F05940g
CAL: CaO19.7645(BPL1)
CTP: CTRG_05783
CDU: CD36_35420
CGR: CAGL0I03806g
YLI: YALI0E30591g
SPO: SPBC30D10.07c
NCR: NCU05516
PAN: PODANSg2869
MGR: MGG_00436
FGR: FG08329.1
ANI: AN6055.2
AFM: AFUA_2G09550
AOR: AO090011000708
ANG: An16g06410
AFV: AFLA_045250
NFI: NFIA_085040
CIM: CIMG_07858
URE: UREG_02182
SSL: SS1G_04467
BFU: BC1G_00456
CNE: CNC00800
CNB: CNBC6470
LBC: LACBIDRAFT_317063
UMA: UM03839.1
MGL: MGL_0053
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:14284697]
SIEGEL L, FOOTE JL, COON MJ.
THE ENZYMATIC SYNTHESIS OF PROPIONYL COENZYME A HOLOCARBOXYLASE FROM
D-BIOTINYL 5'-ADENYLATE AND THE APOCARBOXYLASE.
J. Biol. Chem. 240 (1965) 1025-31.
Oryctolagus cuniculus
Other DBs ExplorEnz - The Enzyme Database: 6.3.4.10
IUBMB Enzyme Nomenclature: 6.3.4.10
ExPASy - ENZYME nomenclature database: 6.3.4.10
BRENDA, the Enzyme Database: 6.3.4.10
CAS: 37318-67-5
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