| Entry |
|
|---|
| Name |
ribose-5-phosphate---ammonia ligase;
5-phosphoribosylamine synthetase;
ribose 5-phosphate aminotransferase;
ammonia-ribose 5-phosphate aminotransferase |
|---|
| Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
 |
|---|
| Sysname |
ribose-5-phosphate:ammonia ligase (ADP-forming) |
|---|
| Reaction(IUBMB) |
ATP + ribose 5-phosphate + NH3 = ADP + phosphate +
5-phosphoribosylamine [RN:R01053] |
|---|
| Reaction(KEGG) |
R01053
 |
|---|
| Substrate |
ATP [CPD:C00002];
ribose 5-phosphate [CPD:C00117];
NH3 [CPD:C00014] |
|---|
| Product |
ADP [CPD:C00008];
phosphate [CPD:C00009];
5-phosphoribosylamine [CPD:C03090] |
|---|
| Pathway |
PATH: ec00230 Purine metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5699059]
Reem GH.
Enzymatic synthesis of 5'-phosphoribosylamine from ribose
5-phosphate and ammonia, an alternate first step in purine
biosynthesis.
J. Biol. Chem. 243 (1968) 5695-701.
duck, Gallus gallus [GN:gga], pigeon |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 6.3.4.7
IUBMB Enzyme Nomenclature: 6.3.4.7
ExPASy - ENZYME nomenclature database: 6.3.4.7
BRENDA, the Enzyme Database: 6.3.4.7
CAS: 9082-52-4 |
|---|
