| Entry |
|
|---|
| Name |
imidazoleacetate---phosphoribosyldiphosphate ligase;
5-phosphoribosylimidazoleacetate synthetase |
|---|
| Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
 |
|---|
| Sysname |
imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and
diphosphate-forming) |
|---|
| Reaction(IUBMB) |
ATP + imidazole-4-acetate + 5-phosphoribosyl diphosphate = ADP +
phosphate + 1-(5-phosphoribosyl)imidazole-4-acetate + diphosphate
[RN:R04068] |
|---|
| Reaction(KEGG) |
R04068
 |
|---|
| Substrate |
ATP [CPD:C00002];
imidazole-4-acetate [CPD:C02835];
5-phosphoribosyl diphosphate [CPD:C00119] |
|---|
| Product |
ADP [CPD:C00008];
phosphate [CPD:C00009];
1-(5-phosphoribosyl)imidazole-4-acetate [CPD:C04437];
diphosphate [CPD:C00013] |
|---|
| Pathway |
PATH: ec00340 Histidine metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14235540]
CROWLEY GM.
THE ENZYMATIC SYNTHESIS OF 5'-PHOSPHORIBOSYLIMIDAZOLEACETIC ACID.
J. Biol. Chem. 239 (1964) 2593-601.
Oryctolagus cuniculus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 6.3.4.8
IUBMB Enzyme Nomenclature: 6.3.4.8
ExPASy - ENZYME nomenclature database: 6.3.4.8
BRENDA, the Enzyme Database: 6.3.4.8
CAS: 37318-65-3 |
|---|
