KEGG   Escherichia coli O7 K1 CE10: CE10_0077
Entry
CE10_0077         CDS       T01999                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
eoc  Escherichia coli O7:K1 CE10
Pathway
eoc00290  Valine, leucine and isoleucine biosynthesis
eoc00620  Pyruvate metabolism
eoc01100  Metabolic pathways
eoc01110  Biosynthesis of secondary metabolites
eoc01210  2-Oxocarboxylic acid metabolism
eoc01230  Biosynthesis of amino acids
Module
eoc_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:eoc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CE10_0077 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CE10_0077 (leuA)
Enzymes [BR:eoc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CE10_0077 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AEQ10932
Position
complement(90755..92326)
AA seq 523 aa
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF
LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA
EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgagccagcaagttattattttcgataccacattgcgcgacggtgaacaggcgttacag
gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt
gacgtgatggaagtcggtttccccgtctcttcgccgggcgatttcgaatcggtgcagacc
atcgcccgccaggtcaaaaacagccgcgtatgtgcgttagctcgctgcgtggaaaaggat
atcgacgtggcagctgaatctctgaaagttgccgaagccttccgtatccatacctttatt
gccacttcaccaatgcacattgccaccaagctgcgtagcacgctggacgaagtaatcgaa
cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc
gaagatgccggacgcacacccattgccgatctggcgcgcgtggttgaagcggcgattaac
gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccgtttgagttc
gctggaatcatcagcggcctgtatgaacgcgtgcctaacatcgacaaagccattatctcc
gtacatacccacgacgatttaggcctggcagttggcaactcactggcggcggtacatgcc
ggagcgcgccaggtggaaggtgcaatgaatgggatcggcgagcgagccggtaactgttcg
ctggaagaagtgatcatggcgatcaaagttcgtaaggatattctcaacgttcataccgcc
attaatcaccaggagatatggcgcaccagccagttagttagccagatttgtaatatgccg
atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtatccac
caggatggtgtactgaaaaaccgtgaaaactacgaaatcatgacaccagaatctattggt
ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc
atggatgagatgggatataaagaaagtgaatataatttagacaacctgtacgacgctttc
ctgaagctggcggacaaaaaaggccaggtgtttgattacgatctggaggcgctggccttc
atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtca
ggttctaacgatattgccactgccgccgtcaaactggcctgtggcgaagaagtcaaagca
gaagccgccaacggtaacggtccggtcgatgccgtctatcaggcgattaaccgcatcact
gactataacgtcgaactggtgaaatacagcctgaccgccaaaggtcacggtaaagatgcg
ctgggtcaggtggatattgtcgccaactacaatggtcgccgcttccacggcgtcggcctg
gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtactgaacaatatctgg
cgtgccgcagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag
gaaaccgtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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