KEGG   Equus przewalskii (Przewalski's horse): 103540249
Entry
103540249         CDS       T04644                                 
Symbol
AKT1
Name
(RefSeq) AKT serine/threonine kinase 1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz01521  EGFR tyrosine kinase inhibitor resistance
epz01522  Endocrine resistance
epz01524  Platinum drug resistance
epz04010  MAPK signaling pathway
epz04012  ErbB signaling pathway
epz04014  Ras signaling pathway
epz04015  Rap1 signaling pathway
epz04022  cGMP-PKG signaling pathway
epz04024  cAMP signaling pathway
epz04062  Chemokine signaling pathway
epz04066  HIF-1 signaling pathway
epz04068  FoxO signaling pathway
epz04071  Sphingolipid signaling pathway
epz04072  Phospholipase D signaling pathway
epz04140  Autophagy - animal
epz04150  mTOR signaling pathway
epz04151  PI3K-Akt signaling pathway
epz04152  AMPK signaling pathway
epz04210  Apoptosis
epz04211  Longevity regulating pathway
epz04213  Longevity regulating pathway - multiple species
epz04218  Cellular senescence
epz04261  Adrenergic signaling in cardiomyocytes
epz04370  VEGF signaling pathway
epz04371  Apelin signaling pathway
epz04380  Osteoclast differentiation
epz04510  Focal adhesion
epz04550  Signaling pathways regulating pluripotency of stem cells
epz04611  Platelet activation
epz04613  Neutrophil extracellular trap formation
epz04620  Toll-like receptor signaling pathway
epz04625  C-type lectin receptor signaling pathway
epz04630  JAK-STAT signaling pathway
epz04660  T cell receptor signaling pathway
epz04662  B cell receptor signaling pathway
epz04664  Fc epsilon RI signaling pathway
epz04666  Fc gamma R-mediated phagocytosis
epz04668  TNF signaling pathway
epz04722  Neurotrophin signaling pathway
epz04725  Cholinergic synapse
epz04728  Dopaminergic synapse
epz04810  Regulation of actin cytoskeleton
epz04910  Insulin signaling pathway
epz04914  Progesterone-mediated oocyte maturation
epz04915  Estrogen signaling pathway
epz04917  Prolactin signaling pathway
epz04919  Thyroid hormone signaling pathway
epz04920  Adipocytokine signaling pathway
epz04922  Glucagon signaling pathway
epz04923  Regulation of lipolysis in adipocytes
epz04926  Relaxin signaling pathway
epz04929  GnRH secretion
epz04931  Insulin resistance
epz04932  Non-alcoholic fatty liver disease
epz04933  AGE-RAGE signaling pathway in diabetic complications
epz04935  Growth hormone synthesis, secretion and action
epz04936  Alcoholic liver disease
epz04973  Carbohydrate digestion and absorption
epz05010  Alzheimer disease
epz05017  Spinocerebellar ataxia
epz05132  Salmonella infection
epz05135  Yersinia infection
epz05142  Chagas disease
epz05145  Toxoplasmosis
epz05152  Tuberculosis
epz05160  Hepatitis C
epz05161  Hepatitis B
epz05162  Measles
epz05163  Human cytomegalovirus infection
epz05164  Influenza A
epz05165  Human papillomavirus infection
epz05166  Human T-cell leukemia virus 1 infection
epz05167  Kaposi sarcoma-associated herpesvirus infection
epz05168  Herpes simplex virus 1 infection
epz05169  Epstein-Barr virus infection
epz05170  Human immunodeficiency virus 1 infection
epz05200  Pathways in cancer
epz05205  Proteoglycans in cancer
epz05207  Chemical carcinogenesis - receptor activation
epz05208  Chemical carcinogenesis - reactive oxygen species
epz05210  Colorectal cancer
epz05211  Renal cell carcinoma
epz05212  Pancreatic cancer
epz05213  Endometrial cancer
epz05214  Glioma
epz05215  Prostate cancer
epz05218  Melanoma
epz05220  Chronic myeloid leukemia
epz05221  Acute myeloid leukemia
epz05222  Small cell lung cancer
epz05223  Non-small cell lung cancer
epz05224  Breast cancer
epz05225  Hepatocellular carcinoma
epz05226  Gastric cancer
epz05230  Central carbon metabolism in cancer
epz05231  Choline metabolism in cancer
epz05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
epz05415  Diabetic cardiomyopathy
epz05417  Lipid and atherosclerosis
epz05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103540249 (AKT1)
   04012 ErbB signaling pathway
    103540249 (AKT1)
   04014 Ras signaling pathway
    103540249 (AKT1)
   04015 Rap1 signaling pathway
    103540249 (AKT1)
   04370 VEGF signaling pathway
    103540249 (AKT1)
   04371 Apelin signaling pathway
    103540249 (AKT1)
   04630 JAK-STAT signaling pathway
    103540249 (AKT1)
   04668 TNF signaling pathway
    103540249 (AKT1)
   04066 HIF-1 signaling pathway
    103540249 (AKT1)
   04068 FoxO signaling pathway
    103540249 (AKT1)
   04072 Phospholipase D signaling pathway
    103540249 (AKT1)
   04071 Sphingolipid signaling pathway
    103540249 (AKT1)
   04024 cAMP signaling pathway
    103540249 (AKT1)
   04022 cGMP-PKG signaling pathway
    103540249 (AKT1)
   04151 PI3K-Akt signaling pathway
    103540249 (AKT1)
   04152 AMPK signaling pathway
    103540249 (AKT1)
   04150 mTOR signaling pathway
    103540249 (AKT1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103540249 (AKT1)
  09143 Cell growth and death
   04210 Apoptosis
    103540249 (AKT1)
   04218 Cellular senescence
    103540249 (AKT1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103540249 (AKT1)
   04550 Signaling pathways regulating pluripotency of stem cells
    103540249 (AKT1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103540249 (AKT1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103540249 (AKT1)
   04613 Neutrophil extracellular trap formation
    103540249 (AKT1)
   04620 Toll-like receptor signaling pathway
    103540249 (AKT1)
   04625 C-type lectin receptor signaling pathway
    103540249 (AKT1)
   04660 T cell receptor signaling pathway
    103540249 (AKT1)
   04662 B cell receptor signaling pathway
    103540249 (AKT1)
   04664 Fc epsilon RI signaling pathway
    103540249 (AKT1)
   04666 Fc gamma R-mediated phagocytosis
    103540249 (AKT1)
   04062 Chemokine signaling pathway
    103540249 (AKT1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103540249 (AKT1)
   04922 Glucagon signaling pathway
    103540249 (AKT1)
   04923 Regulation of lipolysis in adipocytes
    103540249 (AKT1)
   04920 Adipocytokine signaling pathway
    103540249 (AKT1)
   04929 GnRH secretion
    103540249 (AKT1)
   04915 Estrogen signaling pathway
    103540249 (AKT1)
   04914 Progesterone-mediated oocyte maturation
    103540249 (AKT1)
   04917 Prolactin signaling pathway
    103540249 (AKT1)
   04926 Relaxin signaling pathway
    103540249 (AKT1)
   04935 Growth hormone synthesis, secretion and action
    103540249 (AKT1)
   04919 Thyroid hormone signaling pathway
    103540249 (AKT1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103540249 (AKT1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103540249 (AKT1)
  09156 Nervous system
   04725 Cholinergic synapse
    103540249 (AKT1)
   04728 Dopaminergic synapse
    103540249 (AKT1)
   04722 Neurotrophin signaling pathway
    103540249 (AKT1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103540249 (AKT1)
  09149 Aging
   04211 Longevity regulating pathway
    103540249 (AKT1)
   04213 Longevity regulating pathway - multiple species
    103540249 (AKT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103540249 (AKT1)
   05205 Proteoglycans in cancer
    103540249 (AKT1)
   05207 Chemical carcinogenesis - receptor activation
    103540249 (AKT1)
   05208 Chemical carcinogenesis - reactive oxygen species
    103540249 (AKT1)
   05230 Central carbon metabolism in cancer
    103540249 (AKT1)
   05231 Choline metabolism in cancer
    103540249 (AKT1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103540249 (AKT1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103540249 (AKT1)
   05212 Pancreatic cancer
    103540249 (AKT1)
   05225 Hepatocellular carcinoma
    103540249 (AKT1)
   05226 Gastric cancer
    103540249 (AKT1)
   05214 Glioma
    103540249 (AKT1)
   05221 Acute myeloid leukemia
    103540249 (AKT1)
   05220 Chronic myeloid leukemia
    103540249 (AKT1)
   05218 Melanoma
    103540249 (AKT1)
   05211 Renal cell carcinoma
    103540249 (AKT1)
   05215 Prostate cancer
    103540249 (AKT1)
   05213 Endometrial cancer
    103540249 (AKT1)
   05224 Breast cancer
    103540249 (AKT1)
   05222 Small cell lung cancer
    103540249 (AKT1)
   05223 Non-small cell lung cancer
    103540249 (AKT1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103540249 (AKT1)
   05170 Human immunodeficiency virus 1 infection
    103540249 (AKT1)
   05161 Hepatitis B
    103540249 (AKT1)
   05160 Hepatitis C
    103540249 (AKT1)
   05164 Influenza A
    103540249 (AKT1)
   05162 Measles
    103540249 (AKT1)
   05168 Herpes simplex virus 1 infection
    103540249 (AKT1)
   05163 Human cytomegalovirus infection
    103540249 (AKT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103540249 (AKT1)
   05169 Epstein-Barr virus infection
    103540249 (AKT1)
   05165 Human papillomavirus infection
    103540249 (AKT1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103540249 (AKT1)
   05135 Yersinia infection
    103540249 (AKT1)
   05152 Tuberculosis
    103540249 (AKT1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103540249 (AKT1)
   05142 Chagas disease
    103540249 (AKT1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103540249 (AKT1)
   05017 Spinocerebellar ataxia
    103540249 (AKT1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103540249 (AKT1)
   05418 Fluid shear stress and atherosclerosis
    103540249 (AKT1)
   05415 Diabetic cardiomyopathy
    103540249 (AKT1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103540249 (AKT1)
   04932 Non-alcoholic fatty liver disease
    103540249 (AKT1)
   04931 Insulin resistance
    103540249 (AKT1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103540249 (AKT1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103540249 (AKT1)
   01524 Platinum drug resistance
    103540249 (AKT1)
   01522 Endocrine resistance
    103540249 (AKT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:epz01001]
    103540249 (AKT1)
Enzymes [BR:epz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103540249 (AKT1)
Protein kinases [BR:epz01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   103540249 (AKT1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like PH Seadorna_VP7
Other DBs
NCBI-GeneID: 103540249
NCBI-ProteinID: XP_008505021
Position
Un
AA seq 457 aa
MGQGFPGPHGWGARVGQVGREEGMCADRMPTCWSPPECQLMKTERPRPNTFIIRCLQWTT
VIERTFHVETPEEREEWTTAIQTVADGLKRQEEEMDFRSGSPSDNSGAEEMEVSLAKPKH
RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ
NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFPEDRARFYGAEIVSALDY
LHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLED
NDYGRAVDWWGLGVVMYEMVCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGL
LKKDPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFT
AQMITITPPDQDDTMEGVDSERRPHFPQFSYSASGTA
NT seq 1374 nt   +upstreamnt  +downstreamnt
atgggacagggcttcccaggaccccatgggtggggtgctcgggtgggccaggtgggccga
gaggagggcatgtgtgcggacaggatgcccacctgctggtcccccccagagtgccagctg
atgaagacggagcggcccaggcccaacaccttcatcatccgctgcctgcagtggaccacg
gtgatcgagcgcaccttccacgtggagacgcccgaggagcgggaggagtggacgactgcc
atccagacagtggctgatgggctcaagaggcaggaggaagagatggacttccgatcgggc
tcacccagtgacaactctggggccgaggagatggaggtgtccctggccaagcccaaacac
cgtgtgaccatgaacgagtttgagtacctgaagctcctgggcaaaggcacctttgggaag
gtgattctggtgaaggagaaggccacgggccgctactacgccatgaagatcctgaagaag
gaagtcatcgtggccaaggacgaggtggcccacacgctcacggagaaccgcgtgctccag
aactcccggcatcccttcctgacggctctcaagtactccttccagacccatgaccgcctg
tgcttcgtcatggagtacgccaacgggggcgagctcttcttccacctgtcccgggagcgc
gtgttccccgaggaccgggcccgcttttacggcgccgagatcgtgtcggccctggactac
ctgcactctgagaagaatgtcgtctaccgtgacctcaagctggagaacctcatgctggac
aaggacgggcacatcaagatcactgactttgggctgtgcaaggagggcatcaaggatggg
gccaccatgaagaccttctgcgggacacctgagtacctggcccccgaggtgctggaggac
aacgattacggccgggcggtggactggtgggggctgggcgtggtcatgtacgagatggtg
tgcggccgcctgcccttctacaaccaggaccacgagaagctcttcgagctcatcctcatg
gaggagatccgcttcccgcgcacgctcagccctgaggccaagtccctgctctcggggctg
ctcaagaaggaccccaagcagaggctgggcgggggctccgaggacgccaaggagatcatg
cagcaccgcttctttgccagcatcgtgtggcaggacgtgtatgagaagaagctcagcccg
cccttcaagccccaggtcacatcggagacagacaccaggtattttgatgaggagttcacg
gcccagatgatcaccatcacgccgcccgaccaagacgacacgatggagggtgtggacagc
gagcggaggccccacttcccccagttctcctactcggccagcggcacggcctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (100)   
   KEGG PATHWAY (100)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (117)   

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