KEGG   Equus przewalskii (Przewalski's horse): 103540259Help
Entry
103540259         CDS       T04644                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:epz00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    103540259 (INSR)
   04015 Rap1 signaling pathway
    103540259 (INSR)
   04010 MAPK signaling pathway
    103540259 (INSR)
   04066 HIF-1 signaling pathway
    103540259 (INSR)
   04068 FoxO signaling pathway
    103540259 (INSR)
   04072 Phospholipase D signaling pathway
    103540259 (INSR)
   04022 cGMP - PKG signaling pathway
    103540259 (INSR)
   04151 PI3K-Akt signaling pathway
    103540259 (INSR)
   04152 AMPK signaling pathway
    103540259 (INSR)
   04150 mTOR signaling pathway
    103540259 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    103540259 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    103540259 (INSR)
   04923 Regulation of lipolysis in adipocyte
    103540259 (INSR)
   04913 Ovarian Steroidogenesis
    103540259 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103540259 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    103540259 (INSR)
   04213 Longevity regulating pathway - multiple species
    103540259 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    103540259 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    103540259 (INSR)
   04931 Insulin resistance
    103540259 (INSR)
Enzymes [BR:epz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103540259 (INSR)
Protein kinases [BR:epz01001]
 Receptor tyrosine kinases
  INSR family [OT]
   103540259 (INSR)
Cytokine receptors [BR:epz04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   103540259 (INSR)
CD molecules [BR:epz04090]
 Proteins
  103540259 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 742 aa AA seqDB search
MNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAE
LEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWD
WSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELL
TFSHIRTSSDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVD
IDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTNAT
NPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQEEDSELYELDYCLKGLKL
PSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVV
FVPRKSSSGPGAEDTRPSRKRRALADVGNVTVAVPTVPGFPNTSSTSTPTSSEERRPFEK
VVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVSARTMPEAKADDIVGPVTHE
IFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPPGN
YSVRVRATSLAGNGSWTEATYFYVTDYYVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRK
RQPDGPLGPLYASSNPEYLSASDGEYHPLPCGLSESSVRFPLSGESQRMTPQEAEISPPV
PLACRPAPCCWEQLDTCRPAPV
NT seq 2229 nt NT seq  +upstreamnt  +downstreamnt
atgaattccagcaacttgatgtgtaccccgtgcctgggtccctgtcccaaggtgtgccac
ctcctggaaggcgagaagaccatcgactcggtgacgtccgcccaggagctccgaggctgc
acggtcatcaacgggagcctgatcatcaacatccgagggggcaacaacctggcagctgag
ctagaggccaaccttggactcattgaagaaatttcagggtatctgaaaatccgccggtcc
tacgctctcgtgtcgctttccttcttccggaagttacgcctaattcggggagagaccttg
gaaatcgggaactactcattctacgccttggacaaccagaacctgaggcagctatgggac
tggagcaagcacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa
ctctgcttgtcggaaattcacaagatggaggaagtttcaggaaccaaagggcgccaggag
aggaacgacatcgccctgaagaccaacggggaccaggcgtcctgtgaaaatgagttactt
acattttctcacattcggacatcttctgacaagatcttgctgaaatgggagccatattgg
ccccccgacttccgagacctcttgggcttcatgctcttctataaagaggccccttatcag
aacgtgacggagttcgatgggcaggatgcctgtggctccaacagctggacggtagtggac
attgacccacctctgaggtccaacgaccccaagtcacagaaccaccccgggtggctgatg
cgaggtctcaaaccctggacccagtatgccatctttgtcaagaccttggtcaccttttct
gatgaacgccggacatacggggccaagagcgacatcatctatgtccagacaaatgccacg
aacccgtctgtccccctggatcccatctccgtttctaattcctcatcccagattattctg
aagtggaagcccccctctgaccccaatgggaacatcacacactacctggttttctgggag
aggcaggaggaagacagcgagctgtacgagttggattattgcctcaaaggcttgaagctg
ccctccaggacctggtctccaccgtttgagtctgaggggtcccagaagcacaatcagagt
gagtacgaggagtctgccggcgaatgctgctcctgcccgaagaccgactcccagatcctg
aaggagctggaggagtcctcgttcaggaagacgttcgaggactatctgcacaatgtggtt
tttgtccccagaaaatcctcttcaggccctggtgccgaggacactagaccgtctcggaaa
cgcagggcgcttgctgatgtcgggaatgtgacggtggccgtgcccacggttccgggtttc
cctaatacctcctccaccagcacgcccacgagctcagaggagcgcagacccttcgagaaa
gtggtgaacaaggagtcgctggtcatctccggcctgcgccattttaccgggtatcgcatc
gagcttcaggcttgcaaccaagattcccccgaagagaggtgcagtgtggccgcctatgtc
agtgccaggaccatgcctgaagccaaggcggacgacatcgttggccccgtgactcacgaa
atcttcgagaacaatgtcgttcacttgatgtggcaggagcccaaagaacccaacggtctg
atcgtgctgtacgaagtgagttatcggcgatacggcgatgaggagctgcatctctgtgtg
tctcgcagacattttgccctggagcggggctgccggctgcgtgggctgccgccagggaac
tacagtgtgcgagtgcgggccacctccctggcaggcaatggctcctggaccgaagccact
tatttctacgtgacagactattacgtcccatcaaatattgcaaaaatcatcatcggcccc
ctcatctttgtctttctcttcagtgtggtcattggaagcatttacctcttcttgagaaag
aggcagccggatgggcccctgggaccgctgtacgcttcctcaaaccctgagtacctcagc
gccagtgatggtgagtaccatcctcttccctgtgggctgtcagaatcctctgttcggttt
cctttgtctggtgaaagtcaaaggatgacaccccaggaggctgagattagccctcctgtt
cctttagcttgcagacctgccccttgctgctgggagcagttggacacctgccgtcctgca
cctgtttga

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