KEGG   Equus przewalskii (Przewalski's horse): 103562070
Entry
103562070         CDS       T04644                                 
Symbol
MET
Name
(RefSeq) MET proto-oncogene, receptor tyrosine kinase
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz01521  EGFR tyrosine kinase inhibitor resistance
epz04010  MAPK signaling pathway
epz04014  Ras signaling pathway
epz04015  Rap1 signaling pathway
epz04020  Calcium signaling pathway
epz04151  PI3K-Akt signaling pathway
epz04360  Axon guidance
epz04510  Focal adhesion
epz04520  Adherens junction
epz05100  Bacterial invasion of epithelial cells
epz05144  Malaria
epz05200  Pathways in cancer
epz05202  Transcriptional misregulation in cancer
epz05205  Proteoglycans in cancer
epz05206  MicroRNAs in cancer
epz05208  Chemical carcinogenesis - reactive oxygen species
epz05211  Renal cell carcinoma
epz05218  Melanoma
epz05223  Non-small cell lung cancer
epz05225  Hepatocellular carcinoma
epz05226  Gastric cancer
epz05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103562070 (MET)
   04014 Ras signaling pathway
    103562070 (MET)
   04015 Rap1 signaling pathway
    103562070 (MET)
   04020 Calcium signaling pathway
    103562070 (MET)
   04151 PI3K-Akt signaling pathway
    103562070 (MET)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103562070 (MET)
   04520 Adherens junction
    103562070 (MET)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    103562070 (MET)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103562070 (MET)
   05202 Transcriptional misregulation in cancer
    103562070 (MET)
   05206 MicroRNAs in cancer
    103562070 (MET)
   05205 Proteoglycans in cancer
    103562070 (MET)
   05208 Chemical carcinogenesis - reactive oxygen species
    103562070 (MET)
   05230 Central carbon metabolism in cancer
    103562070 (MET)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103562070 (MET)
   05226 Gastric cancer
    103562070 (MET)
   05218 Melanoma
    103562070 (MET)
   05211 Renal cell carcinoma
    103562070 (MET)
   05223 Non-small cell lung cancer
    103562070 (MET)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    103562070 (MET)
  09174 Infectious disease: parasitic
   05144 Malaria
    103562070 (MET)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103562070 (MET)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:epz01001]
    103562070 (MET)
Enzymes [BR:epz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103562070 (MET)
Protein kinases [BR:epz01001]
 Receptor tyrosine kinases (RTK)
  MET family
   103562070 (MET)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 103562070
NCBI-ProteinID: XP_008535230
Position
Un
AA seq 1415 aa
MLPLAAVSSRMHIVSPKTDRATFPVKDKLLTMKAPAVLAPGILVLLFTLVQKSDGECKEA
LVKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGATNYIYVLNDKDLQKVAEYKTGPV
LEHPDCFPCQDCSRKANLSGGAWKDNINMALLVDTYYDDQLISCGSVHRGTCQRHVLPLN
NVADIQSEVYCMYSPQAEEPHQCPDCVVSALGTKVLLSEKDRFVTFFVGNTINSSYLPDH
SLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNHFIYFLTVQRETL
DAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTSEEVFNILQAAYVSKPGAHL
AKQIGANLNDDILYGVFAQSKPDSAEPMNRSAVCAFPVKYVNEFFNKIVNKNNVRCLQHF
YGPHHEHCFNRTLLRNSSGCEVRNDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGN
LTIANLGTSEGRFMQVVVSRSGSSTPHVNFHLDSHPVSPEVIVEHPLNQNGYTLVVTGKK
ITKIPLNGLGCEHFQSCSQCLSAXXXXXXXXXXXXXDKCVRLEECHNRTWTQEICLPTIY
KVFPTSAPLEGGTTLTVCGWDFGFRKNNKLDSKKTKVLLGNESCTLTLSESTSNTLKCTV
GPAMNERFNISITVSNSRGTARYSTFSYVDPIITSISPSYGPKTGGTLLTLTGKYLNSGN
SRHISIGGKTCTLKSVSDSILECYTPAQTTPTEFPVKLKIDLANREMNSFSYREDPIVYE
IHPTKSFISGGSTITGVGKNLNSVSVLRMVINVREAGRNFTVACQHRSNSEIICCTTPSL
QQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDID
PEAVKGEVLKVGNKSCENIHSHSEAVLCTVPSDLLKLNSELNIEWKQAVSSTILGKVIVQ
PDQNFTGLIVGVVSISIILLLLLGLFLWLKRRKQIKDLGSELVRYDARVHTPHLDRLVSA
RSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPL
LQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIH
CAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLR
NFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA
RDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPD
VNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIG
EHYVHVNATYVNVKCVAPYPSLLSSQDNVDGEVDT
NT seq 4248 nt   +upstreamnt  +downstreamnt
atgcttccacttgctgctgtctcatccaggatgcatattgtctcacccaagaccgatcgt
gccactttcccagttaaggataaacttctcaccatgaaggcacctgctgtgcttgcacct
ggcatccttgtgcttctgtttaccttggtgcagaagagcgatggggagtgtaaagaggcg
ctagtaaagtccgagatgaatgtgaacatgaagtatcagcttcccaacttcactgcagaa
acacccatccagaacgtcgttttacacaagcatcacatttacctcggggccactaactac
atttatgttttaaatgacaaagatcttcagaaagttgctgagtacaagactgggcccgtg
ctggaacacccagattgtttcccatgtcaggactgcagccgcaaagccaatttatcaggt
ggcgcttggaaagataacatcaacatggctctgcttgttgacacatactatgacgatcaa
ctcattagttgcggcagcgtccacagagggacctgccagcggcacgtccttccactcaac
aatgttgctgacatacagtcagaagtttattgcatgtactctccacaagcagaagagccc
caccagtgtcctgactgtgtggtgagtgccctgggaaccaaagtcctgctgtctgaaaag
gaccgatttgtcaccttcttcgtgggcaataccataaattcttcttaccttccagatcat
tcattgcattcgatatcggtgagaaggctaaaggaaacgcaagatggttttaagtttttg
acagatcagtcctatattgatgttctacctgagttccgagattcttaccccattaagtat
atccacgcctttgaaagcaaccattttatttactttttaacggtccaacgggaaactcta
gatgctcagacttttcacacaagaataatcaggttctgttccgtggactctggattgcat
tcctacatggaaatgcctctggagtgtattctcacagaaaagagaagaaagagatccaca
agtgaggaagtgtttaatatcctccaagctgcgtatgtcagtaagcctggggctcatctt
gctaagcaaataggtgccaacctgaatgatgacattctctatggggtgtttgcacagagc
aagccagattctgctgaaccaatgaatcgctctgccgtctgtgcattccctgtcaaatat
gtcaatgaattcttcaacaagattgtcaacaaaaacaacgtgagatgtctccagcatttt
tatggaccccaccatgaacactgcttcaataggacacttttgagaaattcatcaggctgt
gaagtgcgcaatgatgaatatcgaacggagtttaccacagctttgcagcgcgttgacttg
ttcatgggccaattcaaccaagtcctcttgacatctatatccaccttcattaaaggaaac
ctcactatagctaatcttgggacatcagaaggtcgcttcatgcaggttgtggtttctcga
tcaggatcgtcaacccctcatgtgaattttcacctggattcccaccctgtgtctccagaa
gtgattgtggaacacccattaaaccaaaatggttacacactggttgtcaccgggaaaaag
atcaccaagatcccactgaatggcttgggctgtgaacatttccagtcctgcagtcagtgt
ctctccgcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngacaaatgtgtg
cgattggaggaatgccacaacagaacatggactcaagagatctgtctgcctacaatctac
aaggttttcccaaccagtgcccccctcgaaggagggacaacgctgacagtatgtggctgg
gactttggattcaggaagaataataaacttgattcaaagaaaaccaaagttctccttgga
aatgagagctgcaccttgactttaagtgagagcacgtcaaatacgttgaaatgcacagtt
ggtcctgcaatgaatgagcgtttcaatatatccataactgtttccaacagtcgagggaca
gcacgatatagtacattttcctatgtggatcctataataacaagtatttctccaagttat
ggtcctaagactggtggcactttacttactttaactggaaagtacttaaacagtgggaat
tctagacacatttcaattggtggaaaaacatgtaccttaaaaagtgtgtcagatagtatt
cttgaatgttatactccagcccaaaccactccaactgagtttcccgttaaactgaaaatt
gacttagccaaccgagagatgaacagcttcagttaccgggaagaccccattgtctatgaa
attcatccaaccaaatcttttattagtggtgggagcacaattacaggtgttggaaaaaat
ctgaattcggttagtgtcctgaggatggtgataaatgtgcgtgaagcaggaaggaacttt
acagtggcatgtcagcatcgctctaattcagagataatctgctgtacaactccttcacta
caacagctgaatttgcaactccctctgaaaaccaaagccttcttcatgttggacgggatc
cattccaaatactttgatctcatttatgtacataatcctgtgtttaagccttttgaaaag
ccagtgatgatctcaataggcaatgaaaatgtactggaaattaagggaaatgatattgac
cctgaagccgttaaaggtgaagtgttaaaagttggaaataagagctgtgagaatatacac
tcacattctgaagccgttttatgtacagtccccagtgacctgctgaaattgaacagcgag
ctaaatatagagtggaagcaagcagtttcttcaaccatccttggaaaagtaatagttcaa
ccagatcagaatttcacaggattgattgttggtgttgtctcaatatcaataatactctta
ttattactcgggcttttcctgtggctgaaaaggagaaagcaaattaaagatctgggcagt
gaattagttcgctatgatgcaagagtacacactcctcatttggataggcttgtaagtgcc
cgaagtgtaagcccaactacagaaatggtttcaaatgaatctgtagactaccgagctact
tttccagaagaccagtttcctaactcatctcagaatggatcatgcagacaagtgcagtat
cctctgacggacctatcccccatcctaactagtggggactctgatatatccagtccatta
ctgcaaaataccgtccacattgacctcagtgctctaaatccagagctggtgcaggcagtc
cagcacgtagtgattgggcctagtagtctgattgtgcatttcaatgaagtcataggaaga
ggacattttgggtgtgtatatcatgggactttgttggacaatgatgacaagaaaattcac
tgtgctgtgaaatccttgaatagaatcactgacataggagaagtttcccagtttctcacc
gagggaattatcatgaaagattttagtcatcccaacgttctctcgctcttgggaatctgc
cttcgaagtgagggatctccactggtggttctaccgtacatgaaacatggagaccttcga
aatttcattagaaatgagacccacaacccaactgtaaaagatcttattggctttggtctt
caagtagccaaaggcatgaaatatcttgcaagcaaaaagtttgtccacagagacttggct
gcaagaaactgtatgctggatgaaaaattcactgtcaaggttgctgattttgggcttgcc
agagacatgtatgataaagaatactatagtgtgcacaacaaaacaggtgcaaaactgcct
gtgaagtggatggctttagagagtctgcaaactcagaagtttaccaccaagtcagatgtg
tggtcctttggcgtgctcctctgggagctgatgacaagaggagcaccaccttatcccgat
gtcaacacctttgatataacagtttacttgttgcaaggcagaaggctcttacaaccagag
tactgcccagatcccttgtatgaagtgatgctaaaatgctggcaccctaaagctgaactg
cgcccatccttttctgaactggtctccaggatatcagcgatattctctactttcatcggg
gagcactacgtccatgtgaacgctacttatgtgaatgtgaaatgtgttgctccatatcct
tctctgttgtcatcacaagataacgttgatggcgaggtagatacatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (22)   
   KEGG PATHWAY (22)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (40)   

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