KEGG   Ehrlichia ruminantium Welgevonden (South Africa): Erum6940
Entry
Erum6940          CDS       T00224                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
eru  Ehrlichia ruminantium Welgevonden (South Africa)
Pathway
eru03030  DNA replication
eru03410  Base excision repair
eru03420  Nucleotide excision repair
eru03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:eru00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    Erum6940 (ligA)
   03410 Base excision repair
    Erum6940 (ligA)
   03420 Nucleotide excision repair
    Erum6940 (ligA)
   03430 Mismatch repair
    Erum6940 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:eru03032]
    Erum6940 (ligA)
   03400 DNA repair and recombination proteins [BR:eru03400]
    Erum6940 (ligA)
Enzymes [BR:eru01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     Erum6940 (ligA)
DNA replication proteins [BR:eru03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     Erum6940 (ligA)
DNA repair and recombination proteins [BR:eru03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     Erum6940 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Erum6940 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     Erum6940 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      Erum6940 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB BRCT HHH_2 PTCB-BRCT DNA_ligase_ZBD RNA_ligase
Other DBs
NCBI-ProteinID: CAH58426
UniProt: Q5HAI7
Position
1173549..1175573
AA seq 674 aa
MTDQEEAKLILDKLNEKIRYHDLLYYTQDSPEISDAEYDDLCHQRSIILEKFPSLNSYYQ
DYIGGDPDSRFSKVKHNERMLSLDNAFNKQDVEKFMVRTRKLLDMKENESLCFSCELKID
GLSFSIIYKNGKLFQASTRGNGYFGENITNNVKTIENLPHTIQNAPDFLEVRGEVYIDRN
DFIQLNNEGKNFANPRNAAAGSIRQLDPTITAQRKLKYCMYTIVNSNCLTQTESLNLLNS
WGFCTNEHTISTDNFEEAINFYNKMYNNRSNISYDIDGIIYKINNIKLQHILGTTSKSPR
WAIAYKFPAIEGKTKLNKISIQVGRTGVLTPIAELAPINIGGVVITRASLHNKSEIERKD
IREGDYVIVKRAGDVIPQVVDVDKSLRTVELAEFNFPTACPACGSTVYQAQQEVSIYCMG
GLFCHNQILEKIRHFVSKDAFNIIGLGKKQLLFFYEYGLITNIIDIFTLEEKINNKNIQL
SSFNGWGEKSINNLLSAINNSKVINLENFIFSLGIRFVGKHIAKILANHFISYKNWYTEM
LKLAQDVNYTINIQQVGLKTINSLRTFFIEQHNLNMINNLVEHLTIIDAQSNSYVSLIHG
KTIVFTGELSSMSRSEAKLKSETAGAKVSSSLSKNTDFLIIGNNPGSKYKKAQSLNIQIL
SEDIWLQYIQPNKV
NT seq 2025 nt   +upstreamnt  +downstreamnt
atgacagatcaagaagaagctaagttgatactagataagctaaatgaaaaaattaggtat
catgatcttttatattacacacaggatagtccagaaataagtgacgcagaatatgatgac
ttatgccatcaaagaagtataattctcgaaaagttcccttcactaaatagttattatcaa
gattatataggtggagatccagactcaaggttttctaaagttaaacacaatgagagaatg
ctatctttagataatgctttcaataaacaagatgtcgaaaaatttatggtgaggaccaga
aaactcttagatatgaaagaaaacgagtcactatgtttctcctgtgaattaaaaattgat
gggctatcattttctataatatataaaaatggaaaattatttcaagcatctacaagaggc
aatggatactttggtgaaaatataacaaataatgttaaaaccattgaaaatctacctcat
accattcaaaatgcaccagattttttagaagtaagaggtgaagtatatatagatagaaat
gatttcatacaattaaataatgaaggaaaaaactttgcaaacccacgtaatgctgcagct
ggttccattaggcaattagaccctactattactgctcaacgtaaactaaaatattgcatg
tacacaatagtaaatagcaattgcctaacacaaacagaatcactaaatctattaaacagt
tggggtttttgtacaaatgaacatacaattagtacagataattttgaagaagctattaat
ttctataataaaatgtacaacaatagaagtaacataagctacgacattgacggaataata
tataaaattaacaacatcaaattacaacatattcttggtacaacaagtaagtctcctaga
tgggctatagcatacaaatttccagcaatagaaggtaaaacaaaattaaataaaatttca
atacaagttggtagaactggagtgctaacacctattgcagaacttgcacccattaatata
ggtggagttgtaataacacgagctagtttacataacaaaagtgaaatagaacgcaaagac
atacgtgaaggagattatgttattgtaaaacgagcaggagatgtaattccccaagtagtt
gatgttgataaaagcttacgaactgtagaattggcagaatttaatttcccaacagcatgc
cctgcatgtggaagcactgtataccaagcacagcaggaagtatccatatactgcatggga
ggattattttgtcacaatcaaattttagagaaaattaggcactttgtgtcaaaagatgca
tttaatattattgggcttggaaaaaaacaactactattcttttatgaatatggtttaatc
acaaatattattgatatatttacactagaagaaaaaatcaacaataaaaacatacaatta
tcctcatttaatggatggggagaaaaatccataaataacctattatctgctataaataac
agcaaagtaattaaccttgaaaactttatcttttctttgggtattagatttgtaggtaaa
catatagcaaagatacttgccaatcattttatatcatataaaaattggtatactgaaatg
cttaaattagcacaagatgttaattatacaattaatatacaacaagtaggattaaagact
ataaattcactaagaacatttttcatagaacaacataatttaaatatgataaataactta
gtagaacacctcacaataatagacgcacaatctaacagctatgtatctctgattcacgga
aaaaccatagtttttactggagaattatcaagtatgtcacggtcagaagcgaaactaaaa
tcagaaactgcaggagcaaaagtttcttcatcattatcaaaaaatacagattttcttatt
ataggtaataatcctggttcaaaatataaaaaagcacaatctcttaacatacaaatctta
agcgaagatatatggttacaatatattcaacctaataaagtataa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (53)   
   KEGG ORTHOLOGY (1)   
   RefGene (50)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (7)   
   Pfam (7)   
All databases (78)   

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