KEGG   Escherichia coli O104 H4 2011C-3493 (EAEC): O3K_21305
Entry
O3K_21305         CDS       T02257                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
esl  Escherichia coli O104:H4 2011C-3493 (EAEC)
Pathway
esl00670  One carbon pool by folate
esl00790  Folate biosynthesis
esl01100  Metabolic pathways
esl01240  Biosynthesis of cofactors
Module
esl_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:esl00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    O3K_21305 (folA)
   00670 One carbon pool by folate
    O3K_21305 (folA)
Enzymes [BR:esl01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     O3K_21305 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AFS76124
UniProt: A0A0E0Y5E3
Position
complement(4398317..4398796)
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gaacagttcttgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgatgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (32)   

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