KEGG   Escherichia coli O104 H4 2009EL-2050 (EAEC): O3M_00535
Entry
O3M_00535         CDS       T02316                                 
Name
(GenBank) dihydrofolate reductase
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
esm  Escherichia coli O104:H4 2009EL-2050 (EAEC)
Pathway
esm00670  One carbon pool by folate
esm00790  Folate biosynthesis
esm01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:esm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    O3M_00535
   00670 One carbon pool by folate
    O3M_00535
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:esm01504]
    O3M_00535
Enzymes [BR:esm01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     O3M_00535
Antimicrobial resistance genes [BR:esm01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    O3M_00535
SSDB
Motif
Pfam: DHFR_1 MYRF_ICA
Other DBs
NCBI-ProteinID: AFS54832
Position
87327..87800
AA seq 157 aa
MKISLISATSENGVIGNGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFDSMGVLPNRKYA
VVSRKGISSSNENVLVFPSIEIALQELSKITDHLYVSGGGQIYNSLIEKADIIHLSTVHV
EVEGDINFPKIPENFNLVFEQFFLSNINYTYQIWKKG
NT seq 474 nt   +upstreamnt  +downstreamnt
ttgaaaatttcattgatttctgcaacgtcagaaaatggcgtaatcggtaatggccctgat
atcccatggtcagcaaaaggtgagcagttactctttaaagcgctcacatataatcagtgg
ctccttgttggaaggaaaacatttgactctatgggtgttcttccaaatcgaaaatatgca
gtagtgtcgaggaaaggaatttcaagctcaaatgaaaatgtattagtctttccttcaata
gaaatcgctttgcaagaactatcgaaaattacagatcatttatatgtctctggtggcggt
caaatctacaatagtcttattgaaaaagcagatataattcatttgtctactgttcacgtt
gaggttgaaggtgatatcaattttcctaaaattccagagaatttcaatttggtttttgag
cagttttttttgtctaatataaattacacatatcagatttggaaaaaaggctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (27)   

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