KEGG T00949: ECSP

Escherichia coli O157 H7 TW14359 (EHEC): ECSP_0076

Entry

ECSP_0076 CDS T00949

Gene name

leuC

Definition

isopropylmalate isomerase large subunit

Orthology

K01703

3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]

Organism

etw Escherichia coli O157:H7 TW14359 (EHEC)

Pathway

etw00290	Valine, leucine and isoleucine biosynthesis
etw00660	C5-Branched dibasic acid metabolism
etw01100	Metabolic pathways
etw01110	Biosynthesis of secondary metabolites
etw01210	2-Oxocarboxylic acid metabolism
etw01230	Biosynthesis of amino acids

Module

etw_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; C5-Branched dibasic acid metabolism [PATH:etw00660]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:etw00290]

SSDB

Motif

Pfam:

Aconitase

Other DBs

NCBI-GI:

254791210

NCBI-GeneID:

8214642

UniProt:

C6UVQ9

Position

complement(84052..85452)

AA seq 466 aa
MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGILLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK

NT seq 1401 nt +upstreamnt +downstreamnt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaat
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctacccagactaaagacattaatgcctgcggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgaactgtatgacctg
aatcacccctatcaagggatcgtccacgtaatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgtgcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgttggcaattatcggtaaaaccggtagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcggatgaccctgtgc
aatatggcaatcgaaatgggcgcgaaagccggtctggttgcacctgacgaaaccaccttt
aactatgtcaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactttgcag
gcagaagagatttcaccgcaggtcacctggggaactaacccaggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgttggcctatatggggctgaaaccgggtattctgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgcaccaactcacgtattgaagatttacgcgcggcggcggaa
atcgccaaagggcggaaagtcgcgccaggcgtacaggcgctggtggttcccggctctggt
ccggtaaaagcgcaggcggaagcagaaggtctggataaaatctttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgtcaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgccgcggctgtgaccggccatttcgcc
gacattcgcaacattaaataa

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (7)   
   KEGG ENZYME (2)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (29)   

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