KEGG   Felis catus (domestic cat): 100037406Help
Entry
100037406         CDS       T02385                                 

Gene name
GCK
Definition
glucokinase (hexokinase 4) (EC:2.7.1.2)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
fca  Felis catus (domestic cat)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100037406 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100037406 (GCK)
   00052 Galactose metabolism
    100037406 (GCK)
   00500 Starch and sucrose metabolism
    100037406 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100037406 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    100037406 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    100037406 (GCK)
   04910 Insulin signaling pathway
    100037406 (GCK)
   04917 Prolactin signaling pathway
    100037406 (GCK)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100037406 (GCK)
   04950 Maturity onset diabetes of the young
    100037406 (GCK)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100037406 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
A2
AA seq 465 aa AA seqDB search
MLDDRARMEATKKEKAEQILADFQLQEADLKKVMWRMQKEMARGLRLETHEEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMHN
VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE
LVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS
ATDCDIVRRACESVSTRAAYMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK
ERFHAIVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt
atgctggacgacagagccaggatggaggccaccaagaaggaaaaggcagagcagatcctg
gcggacttccagctgcaggaggccgacttgaagaaggtgatgtggcggatgcagaaggag
atggcgcgaggcctgcggctggagacccacgaggaggccagcgtgaagatgctgcccacc
tacgtgcgctccaccccggaaggctctgaagttggggacttcctctccctggacctgggc
ggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaagaggggcagtggagc
gtgaagaccaagcaccagatgtattccatccccgaggacgccatgacgggtactgctgag
atgctctttgactacatctctgagtgcatctccgacttcctggacaagcaccagatgaag
cacaagaagctgcccttgggcttcaccttctccttccccgtgaggcacgaggacatcgac
aagggcatcctcctcaattggaccaagggcttcaaggcctcaggagcagaagggaacaac
atcgtggggctcctacgtgatgccatcaaacggagaggggactttgaaatggacgtggtg
gcgatggtgaatgacactgtggccacgatgatctcctgctactatgaagaccgccggtgt
gaggttggcatgattgtgggaacaggctgcaatgcctgctacatggaggagatgcacaac
gtggagctggtggaaggggacgagggccgcatgtgcgtcaacaccgagtggggcgccttc
ggggactccggagagctggacgagttcctgctggagtacgaccgcgtggtggacgagaac
tccctgaaccccgggcagcagctatacgagaagctcatcggcggcaagtacatgggcgag
ctggtgcggctcgtgctgctgaagctcgtggacgagaacctgctcttccgcggggaggcc
tcggagcagctgcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggagagc
gactcgggcgaccgcaagcagatctacaacatcctgagcactctggggctgaggccctca
gccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacacgcgccgcgtac
atgtgcgccgcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgaggac
gtgatgcgcatcaccgtgggcgtggacggctctgtgtacaaactgcaccccagcttcaag
gagaggttccacgccatcgtgcgcaggctgacgcccagctgcgagatcaccttcatcgag
tcggaggaaggcagcggccgaggcgccgccctggtgtccgcggtggcctgtaagaaggcc
tgcatgctgggccagtga

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