KEGG T02385: 100113473

Felis catus (domestic cat): 100113473

Entry

100113473 CDS T02385

Gene name

PRF1, perforin

Definition

perforin 1 (pore forming protein)

Orthology

K07818

perforin 1

Organism

fca Felis catus (domestic cat)

Pathway

fca04650	Natural killer cell mediated cytotoxicity
fca04940	Type I diabetes mellitus
fca05320	Autoimmune thyroid disease
fca05330	Allograft rejection
fca05332	Graft-versus-host disease
fca05416	Viral myocarditis

Class

Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:fca04650]
Human Diseases; Immune diseases; Autoimmune thyroid disease [PATH:fca05320]
Human Diseases; Immune diseases; Allograft rejection [PATH:fca05330]
Human Diseases; Immune diseases; Graft-versus-host disease [PATH:fca05332]
Human Diseases; Cardiovascular diseases; Viral myocarditis [PATH:fca05416]
Human Diseases; Endocrine and metabolic diseases; Type I diabetes mellitus [PATH:fca04940]

SSDB

Motif

Pfam:

MACPF C2

Other DBs

NCBI-GI:

156071445

NCBI-GeneID:

100113473

UniProt:

A7LLU2

Position

AA seq 555 aa
MGACVLLPGLLLLLLPRPAPAPCHTAARSECRRNRPFVPGSMLAGEGVDVTSLRRSGSFP
VDTESFLRPDGTCTLCHNVLKQGALQRLPLALTDWRAQGSGCQRQVVRAKASSTEAVARE
AASNIRNDWRVGLDVSPKPSANVHVTVAGSHSHMANFAAQKTFHDQYSFSTDLVECRFYS
SHLVHSPPLHPNFQRVVRDLPPDFNTSTEADYLRLISNYGTHFIRSMELGGRISALTALR
TCELALDGLGAKEVEDCLAVEAQVSISGRADSSSELKACEEKKKHHKITTSFHQAYRERF
SEIVGGHHTSVSDLLFGDQAGPEQFSAWVASLLDRPSLVDYTLEPLHVLLESQDPRREAL
RQAVSKYVMDRARWKDCSRPCPLGQKKSPHNPCQCVCHGSAVTNQDCCPRQRGLAHLEVM
NFQASGLWGDSFTRTDAYLKVFFGGQELRVGTVWNDNNPKWMTRLDFGDVILSTGGPLRV
QVWDQDHGWDDDLLGTCDQNPRSGLHEVRCGLSHGHLRFSYHAKCLPHLKGATCLEYAPH
GLLGELPGNRSGPVW

NT seq 1668 nt +upstreamnt +downstreamnt
atgggtgcctgcgtgctcctcccaggcctcctcctcctgctgctgccccgccccgcccca
gccccctgccacacggccgcccgctccgagtgccgccgcaaccgtccgtttgtgcccggc
tcaatgctggctggggagggcgtggacgtgaccagtctcaggcgctcgggctccttcccg
gtggacacagagagcttcctgcggcccgacggcacctgcactctctgccacaacgtcctg
aaacagggcgcccttcagcgcctccctctggcactgactgactggcgcgcccagggctca
ggctgccagcgccaagtggtcagggccaaggccagttccaccgaggccgtggccagggaa
gcagccagcaacatccgcaacgactggcgggtggggctggacgtgtctcccaaacccagc
gccaacgtgcatgtgaccgtggctggctcgcactcccacatggccaacttcgcggcccag
aagaccttccacgaccagtacagcttcagcactgacttggtggaatgtcgcttctacagc
tctcacctggtacactctcccccactccaccccaatttccagagggtcgtcagagacctg
ccccccgacttcaacacctccaccgaggccgactacctccggctcatctccaactacggc
acccacttcatccggtccatggagctgggcggccggatctcggccctcaccgccctgcgc
acctgtgagctggccctggatgggctcggggccaaagaggtggaggactgcctggccgtc
gaggcccaggtcagcataagtggccgtgccgactcttcatcggaactcaaggcctgtgag
gagaagaagaagcaccacaagataaccacctccttccaccaggcctatcgggagcgcttt
tccgaaatagttggcggccaccacacctccgtaagtgacctgctgtttggggaccaggcc
gggcccgagcagttctcggcctgggtggcctcgctgctggacagacccagcctggtggac
tacaccctggagcctctgcatgtgctcctggagagccaggacccgcggcgggaggccctg
cgacaggccgtgagcaagtacgtgatggacagggcccgctggaaggactgtagcaggcct
tgccccctggggcagaagaagagcccccacaacccatgccagtgtgtctgccacggctca
gcggtcaccaaccaggactgctgtccccggcagaggggcctggcccacttggaggtcatg
aacttccaggcgtcaggcctgtggggagactctttcactaggacggacgcctacctgaag
gtcttctttggaggccaggagctgagagtgggcacagtgtggaacgataacaaccccaag
tggatgacgcggctggacttcggggacgtgatcctgtccaccgggggtcccctgagggtg
caggtctgggaccaagaccacggctgggacgatgacctcctcggcacctgtgaccagaac
ccacggtctggcttgcacgaggtgaggtgtggcctgtcccacggtcacctgagattctcc
taccatgccaagtgcttgcctcacctgaagggggccacctgcctggagtatgccccccac
ggtcttctgggggagcttcccggaaaccggagtgggccggtgtggtga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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