KEGG   Felis catus (domestic cat): 101085029Help
Entry
101085029         CDS       T02385                                 

Gene name
SETD2
Definition
(RefSeq) histone-lysine N-methyltransferase SETD2
  KO
K11423  histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00310  Lysine degradation
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    101085029 (SETD2)
Enzymes [BR:fca01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     101085029 (SETD2)
Chromosome and associated proteins [BR:fca03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     101085029 (SETD2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SRI SET WW
Motif
Other DBs
NCBI-GeneID: 101085029
NCBI-ProteinID: XP_023103989
Ensembl: ENSFCAG00000019287
Position
A2
AA seq 2563 aa AA seqDB search
MKQLPPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFFKGPMFKGVASSRFLPKGTK
TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQNDTPNSPAGPLQVDLTPKIKMDV
GDTLSTTEESSPPKSRVELGKIHFKKHLLHVTSRPLLTTATAVVSPPPPVVPLPAVIAES
TTVDSPPSSPPPPPPPPQATTPSPAPVTEPVALPHTPIPVLMTAPVDVAVRTLKEPPVTT
VPESSDVDTKQDAVSNSSEEHITQNLNEQADTPSQKEDSHIGKEEEIPDSSKSNLGSKKT
GSKKKSSQSEGTFLASESDEDSVRTSSSQRSHDLKFSASIEKERDSKKSLAPLKSEDLGK
SSRSKTERDDKYFSYSKLERDTRYISSRCRSERERRRSRSRSRSDRGSRTSLSYSRSERS
HYYDSDRRYHRSSPYRERARYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSFSYRDLRT
SSSYSKSDRDCKTESSYLEMEKRGKYSSKVERESKRTSENEAMKRCCSPPNELGFRRGSS
YSKHDNSASRYKSALSKSVSKSDKFKNSFCCTELNEEIRSSHSFNLQAPCSKGSELRMIS
KIPEREKTGSPSPSNRLNDSPTFKKLDESLIFKSEFIGHDSHDSIKELDSLSKVKNDQLR
SYCPIELNINGSPGAESDLATFCTSKTDTVLMSSDDSVTGSEVSPLVKACMLSSNGFQNI
NRCKEKDSDNTCMLRSKSGSPFRETEPTVSPHQDKLMSLPVTTIDYSKTVIKEPVDMAVS
CCKTKDSDLYCTSNDNNPSLRHSEAEKIEPSVMKISSNSFMNVHLKSKTVICDDRNLTDQ
HSKFAREEYKQSVGSTSSASVNHFDDIYQPIESSGVASSLQSLPPGVKVDSLTLLQCGEN
ASPVLDAVLKSKSTEFVKHAEKETIIEVGSDLPDSGRGFASWENRHNNGLSGKCVQEAQE
EGSSIVLERRGRSEISLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDGITYTLKCDSS
GHASEIVSTVHEDYSGSSESSSDESDSEDTDSDDSSFPRNRLQSVVVVPKNSTLPTEETS
PCSSRSSQSYRHYSDHWEDERLESRRHSYEEKYDSVASKPCSQTEKFFHHKGTEKNPEIS
FTHPSRKQIDNHLSEIVHPQSDGVDSTSHTDVKSDFLGHPNSEETAKAKIASRQQEELPV
YSSDDFEDIPNKSRQQTIFPNRPDSRLGKTELSFSSSCEISRVDGFRSSEELRNLGWEFS
QQEKPTTTYQQPDSSYGACGGHKYQQSAEHYGGTRNYWQGNGYWDPRSAGRPPGTGVVYD
RIQGQVPDSLTDDREEEDSWDQCAGSHFSSQSSKFFLSLQKDKGSVQAPEISSNSIKDSL
AVNEKKDLSKNLEKNDMKDRGPPKKRRPELESDSESDGELQDRKKVRVAVEQGETALPPG
SALVGPSCVMEDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCEC
APLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKG
WGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKG
NCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCG
SANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRL
MVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEII
KTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAIPPLSEGDGYSSENTSRAHTPLNTPDPS
TKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLEHVPVEDEE
ELQSQQLLTQQLPESKVESEIAMEASKLPISEPEADAEIEPKEGNGTKLEETIAEETPSQ
DEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTITERG
RDAVGFRDQTAAPKTPNRSRERDPDKQTQNKEKRKRRGSLSPPSSAYERGTKRPDDRYDT
PTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAPH
HPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHSQPLVGHSTEPLAAPP
PVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVTVLPVPAPGPVQGQNYGVWDSNQQSVS
VPQQYSPAQSQATIYYQGQTCPAVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHP
QGVVVQPAAAVTAIVTPGQPQPLQPPEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDP
EGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKTSKKPKTAEAD
TSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKEL
KYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
NT seq 7692 nt NT seq  +upstreamnt  +downstreamnt
atgaagcagctgccgccgcagccgcctccgaagatgggggatttctacgaccccgagcac
ccgacccctgaagaagaagaaaatgaggcaaagattgaaaatgtgcagaaaacaggtttc
ttcaaaggaccaatgttcaaaggtgttgcttctagtcgatttttacctaaaggcaccaag
acaaaagttaatttggaggaacagggacgacaaaaggtgtctttcagcttcagccttaca
aagaaaactttgcagaataggtttctgactgcacttggcaatgaaaagcaaaatgatact
ccaaactccccagctggacctcttcaagtagacttgactcctaaaattaaaatggacgtt
ggagataccttatctactacagaagaatcttccccaccaaaatcaagggtagaattgggc
aaaattcattttaagaaacacctgcttcatgtgacgtccaggccactgctgactacagcc
acagcagtggtgtctccacctcctccagtagtaccattaccagcagtcatagcagaatca
acaactgtagattcaccaccctcttctccacctccaccacctccacctccccaggccacg
acaccctcaccagcaccagtaacagagccagtggccttgccacacacaccaatcccagtt
ctgatgacagcaccggtagatgtagcagttagaacactgaaggaaccaccagttacgact
gtaccagaatcttcagacgtggacactaagcaggacgctgtatctaatagttcagaagaa
cacataactcagaatttgaatgagcaagcagatactccctcacaaaaagaagattcccat
attgggaaggaagaagaaattccagatagttctaagagtaatctgggctctaaaaaaaca
ggttctaagaagaaatcctcacaatccgaaggcacctttcttgcttcagaatctgatgaa
gattctgtacggacttcctcaagtcaaagatcacacgatttaaaattttcagcaagcatt
gaaaaggaaagagattcaaaaaagagcttagcacctttaaaaagtgaggatttagggaaa
tcttcacgatctaaaacagagagagatgataaatattttagctactcaaaacttgaaaga
gatactcggtatatatcttctcgatgtagatcagagagagagcgaaggcggagcagatct
cgttcaagatctgacagaggctctagaactagtttatcctattcccggtcggaacgatcc
cattattatgactctgatcgtcgctaccatcggagttccccttaccgagagagggctcgc
tattctcggccatatacagataacagagctcgggagagttctgactcagaagaggagtat
aagaagacctactcaaggcgcacctcatcccattccttctcttacagagacctaaggaca
tcatcatcctattctaaatctgatcgggactgcaaaactgagtcctcttacttagagatg
gagaaaagaggaaagtattcttcaaaagtagaaagagaatccaaaaggacttcagaaaat
gaagcaatgaaaagatgttgttctccccctaatgaactgggattccgacggggctcatcc
tattccaagcatgataacagtgcttcccgttacaaatctgccctttcaaagtctgtatcc
aagtccgataaatttaagaattctttctgttgtacagaattaaatgaggaaatcagatca
tctcattcttttaatttacaggctccttgttcaaaaggtagtgaattaagaatgattagt
aaaattcctgaaagagaaaagactgggtctccatcaccatcaaatcgattaaatgattca
cctacttttaaaaagctagatgaatcccttatttttaaatctgaatttataggacatgat
agccatgatagtattaaggaattagactctttatctaaagtgaagaatgatcagttaaga
agttattgtcccatagaattaaatataaatggatctcctggggcagaatctgatttggca
acattttgcacttctaaaactgacactgttttgatgtcttctgatgatagtgtgactgga
tcagaggtatcccctttggtcaaagcatgcatgctttcatcaaatggatttcagaatatt
aatagatgtaaagagaaagactcagacaatacatgcatgctgcgtagtaagtcaggaagc
ccatttagagaaacagaacctacagtgtcgccacaccaagataaactcatgtctttgcca
gttacgactatagattattccaaaactgtaattaaagaaccagtcgatatggcagtttct
tgttgtaaaaccaaagattcagatctatactgtacttcaaatgacaacaacccttctttg
cgtcattctgaagctgaaaagattgagccttcggttatgaagatttcttcaaatagcttt
atgaatgtgcatttgaaatcaaaaacagttatatgcgatgatagaaatctgacagatcag
cactcaaaatttgcacgtgaagaatataagcagagcgttggtagcaccagttcagcttct
gttaatcattttgatgacatatatcaaccgatagagagttcaggcgttgcttcatctctt
cagagtctgccaccaggagtaaaagtggacagtttaactctcttacaatgtggagagaac
gcatctccagttttggatgctgtgctgaagagtaaaagcacagagtttgtaaagcatgca
gagaaagaaaccatcatagaagtaggtagcgaccttcctgattcaggaaggggatttgcc
tcttgggaaaacaggcataataatgggctctctgggaaatgtgtgcaagaggctcaagaa
gaagggagttccatagtgcttgagagaagaggaaggtcagaaatctctttagatgaagaa
ggagggagaggacatgctcatacttctgatgactcagaagttgtattttcttcttgtgac
ttgaatttaaccatggaggacagtgatggcataacatataccttaaaatgtgacagtagt
ggtcacgcctcagagatcgtatccactgtccatgaagattattctggttcttctgaaagc
tcaagtgatgaaagtgactctgaagatacagattctgatgatagcagttttccaagaaac
cgtcttcagtctgttgtggtagtcccaaagaattctactttgcccacggaagaaaccagt
ccgtgttcttctcggagtagtcaaagttacagacactattctgaccactgggaagatgag
agattggagtcgaggagacattcatatgaggaaaaatatgacagtgtagcaagtaaaccc
tgttctcagacagagaagttcttccatcataaaggaacagagaagaatccggaaatttct
tttacacaccccagcagaaaacagatagataaccacctgtctgaaattgttcatcctcag
agtgacggggttgatagtacaagtcatacagatgtgaaatctgactttctaggtcatcca
aattctgaggaaacagcaaaagccaaaatagcctctaggcagcaagaagagctgccagtt
tattcttctgacgattttgaagacatcccgaataagtctcggcaacaaaccattttccct
aacaggccagatagtagactgggaaaaacagagttgagtttttcttcctcttgtgagatc
tcccgagtggatggcttccgctcatcagaagagctcaggaacctagggtgggaattctct
caacaagaaaagcctactaccacatatcagcaacctgacagcagctatggagcctgtggt
ggacacaagtatcagcaaagtgcagaacattatggtgggacacgtaattactggcaaggt
aacggctactgggatccaagatcagcaggtagacctcctggaacaggggttgtgtatgat
cgaattcaagggcaggtaccagattccttaacagatgaccgtgaagaggaggacagttgg
gatcaatgtgcagggtctcacttttcaagccagtccagtaaattttttctatctcttcag
aaggacaaggggtccgtgcaggcacctgaaataagcagcaattccattaaggactcttta
gctgtgaatgaaaagaaagatctttcaaaaaacttagaaaaaaatgatatgaaagataga
ggacctcctaaaaaaaggagaccggaattggagagtgattctgaaagcgatggtgaactt
caggacagaaagaaagttcgagtggcagtagagcagggagaaacggcattgcccccaggc
tcagcactggttgggccttcctgtgtcatggaggatttcagggacccacagcgatggaaa
gaatgtgccaagcaagggaagatgccctgttactttgatctgattgaagaaaatgtttat
ttaacagaaagaaagaagaataaatcacatcgggatattaagcgaatgcagtgtgagtgt
gcacctctttctaaagatgaaagagcgcaaggtgaaatagcatgtggggaagattgtctt
aatcgactcctcatgattgaatgttcttctcggtgtccgaatggggattattgttccaat
agacggtttcagagaaaacagcatgcagatgtggaagtcatactcacagaaaagaaaggc
tggggcttgagagctgcgaaagaccttccttcgaacacctttgtcctggaatattgtgga
gaggtacttgatcataaagagtttaaagcccgggtaaaggagtatgcacgaaacaaaaac
atccactactatttcatggccctgaagaatgatgagataatagatgccactcagaaagga
aactgctctcgtttcatgaatcacagctgtgaaccaaactgtgagactcaaaaatggact
gtgaacggacaactgagggtcgggttttttaccaccaaattagttccttcaggctcggag
ttaacatttgactatcagttccaaagatatggaaaagaagctcagaaatgtttctgtggg
tcagctaattgccgaggttacctgggaggagagaatagagtcagtatcagagcagcagga
ggaaaaatgaagaaggaacgatctcgtaagaaggattcagtggatggagagctagaagct
ctgatggagaatggtgagggtctctctgataaaaaccaggtgctcagcttatcccggcta
atggttagaattgaaactttggagcagaaacttacctgtcttgagctcatacagaacacg
cattcacagtcttgcctgaagtcctttctggaacgtcatgggctgtctttgttgtggatc
tggatggcagagctaggtgatggccgggaaagtaaccagaagcttcaagaagagattata
aagactttggaacacttacccattcctactaaaaatatgttggaggaaagcaaagtactt
ccaattatccaacgctggtctcagaccaaaactgccattcctccgttgagtgaaggagat
gggtattcaagtgagaatacgtcacgtgctcacacaccactcaacactcctgatccttcc
accaagctaagcacagaagctgacacagatacccccaagaagctcatgtttcgcagactt
aaaattataagtgaaaatagcatggacagtgcaatatctgatgctaccagtgagctggaa
ggcaaggatggcaaagaggaccttgaccagttagaacacgtccctgtagaagacgaggaa
gagttacagtcacaacagctactcacacaacagctgcctgagtctaaagttgagagtgaa
attgccatggaagccagtaagctacccatatctgaaccagaggctgatgctgaaatagag
cctaaagagggcaatggcacgaaactggaagaaacaattgctgaggaaacaccatcccaa
gatgaagaggagggtgtatctgatgtggagagtgagaggagccaggaacagccagataaa
acagtagatataagtgatttggccaccaagctcctggatagttggaaagacctaaaggag
gtttatcgaattccaaagaaaagtcaaactgaaaaggagaacacaataactgaacgagga
agggatgctgttggcttcagagatcaaacagctgccccaaagactcctaacaggtcaaga
gagagagacccagacaagcaaactcaaaataaagagaaaaggaaacgaaggggctctctc
tcaccaccttcttctgcctatgagcggggaacaaaaaggccagatgacagatatgataca
ccaacttctaagaagaaagtacgaattaaagaccgcaataaactttctacagaggagcgc
cggaagttgtttgagcaagaggtggctcagcgggaggctcagaaacaacagcagcagatg
cagaacctgggaatgacatctccactgccctatgactctctgggctacaatgcccctcat
cacccctttgctggctacccaccaggttatcccatgcaggcctatgtggatcccagcaac
cctaatgctggaaaggtgctcctccccacacctagcatggaccccgtgtgttctcctgct
ccttatgatcattctcagcccttggtgggacattctacagaaccccttgctgcccctcca
cctgtaccagtggtgccacatgtggcagcccctgtggaagtttccagttcacagtatgtg
gcccaaagtgatggtgtggtacaccaagactccagcgtcaccgtcttgccagtgccagcc
ccaggcccagttcagggacagaattatggtgtttgggattcaaaccaacagtctgtcagt
gttccccagcagtattctcctgcacagtctcaagcaaccatatattatcaaggacagact
tgtccagctgtctatggtgtgacatcaccctattcacagacaactccaccaattgtgcag
agttatgcccaaccaagtcttcagtacatccaaggacagcagattttcacagctcatccg
caaggcgtggtcgtacagccagctgcagccgtgactgcgatagtcacaccagggcagcct
cagcccttacagccgcctgaaatggtagtgacaaataatcttctggatctgccacccccc
tctcctcccaaaccaaaaaccattgtcttacctcccaactggaagacagcccgagatcca
gaagggaagatttattactaccacgtgatcacaaggcagactcagtgggatcctcctact
tgggaaagcccaggagatgatgccagccttgagcatgaagctgagatggacctggggacc
ccaacgtatgatgaaaaccccatgaagacatcaaaaaagcctaagacagcagaagcagac
acctccagtgagctggctaagaaaagcaaagaagtattcagaaaagagatgtcccagttc
atcgtccagtgcctgaacccttaccggaaacctgactgcaaagtgggaagaatcaccaca
actgaagacttcaaacacctagctcgcaagctgactcacggcgttatgaataaggagctg
aagtactgtaagaaccctgaggacctggagtgcaatgagaatgtgaaacacaaaaccaag
gagtatattaagaagtacatgcagaagtttggggctgtttacaaacccaaagaggacact
gaattagagtga

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