KEGG   Felis catus (domestic cat): 101088695Help
Entry
101088695         CDS       T02385                                 

Gene name
PLCE1
Definition
(RefSeq) phospholipase C, epsilon 1
  KO
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Thyroid hormone signaling pathway
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101088695 (PLCE1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101088695 (PLCE1)
   04015 Rap1 signaling pathway
    101088695 (PLCE1)
   04020 Calcium signaling pathway
    101088695 (PLCE1)
   04070 Phosphatidylinositol signaling system
    101088695 (PLCE1)
   04024 cAMP signaling pathway
    101088695 (PLCE1)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    101088695 (PLCE1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    101088695 (PLCE1)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101088695 (PLCE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
D2
AA seq 1808 aa AA seqDB search
MMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQNIYRRVLPV
DYLCFLTRDLGSPECQTSLPCLKASISASILNSQNGEHNALEDLVMRFNEVSSWVTWLIL
TAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDLETMRS
LKDAMAQHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLCPRYNSQ
EETLEFVADYSGQDHFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRSLEAEEEDSPSEGN
SSRKNSLRDKARWQFIIGDLLDSENDIFEKSKEWDAHGSEEPQKAFDHGTELIPWYVLSI
RADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTASLASAKAKLGVLSN
TSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLGSMFLSETGVT
LLYGLQTTDNRLLHFVAPRHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQYVSLYQE
DGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNVQRNNTLGISTTKKKKKILIR
GESGEAADDEMATRKAKMHRECRSRSGSDPQDMNEQEESEANAIMSPPNTLPSRRAHSLT
TAGSPNLSAGTSSPNRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGFQSFMVSDSNM
SFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESVPLYTNLTIDENTSDLQPDLDL
LTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGVGILQLNDFL
VNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNFASKNDESQENIKE
LQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGLPIIYHG
HTLTTKIPFKEVVEAIERSAFVNSDLPIIISIENHCSLPQQRKMAEIFKSVFGEKLVAKF
LFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAYNGGNAN
PPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRIKKADNS
ACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASGSSRGKE
RKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQAWEESSSPLNPTTSLSAIIRTPK
CYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVA
LNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNMEPAIYSL
TIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRVHFEDL
VFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRMEENSS
SSTTPASLMFNSEERKCLQAHRVTVHGVPGPEPFTVFSISGGTKAKQLLQQVLTTEQDTK
PIITDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPEEGYVGRIVLKTQQ
ENLEEKSIVQDDKEVTLSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAK
YSYSILSNPNPSDYVLLEEVVKDTTKKSSTPKSSQRVLLDQECVFQAQSKWKGAGKFILK
LKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLASPSQVLALEGVQNKEEKPMGSLSS
SDTMDYRQ
NT seq 5427 nt NT seq  +upstreamnt  +downstreamnt
atgatgctaaaagaacgtcagccaggcacctccatggccaattctagtgccctcccttca
agttcagctgggatcagcaaggagctgattgatctgcagcccctcattcagttcccagag
gaagtcgccagcatcctgatggagcaggagcagaacatttaccgaagggtcttgccagtt
gactacctttgcttcttgacccgggacttgggctctccagaatgccagacatccctgccc
tgcctcaaagcgtccatctcagcatcaattcttaactcccagaacggagaacacaatgcc
ctggaagatcttgtgatgagatttaatgaggtgagctcctgggtaacgtggctgatcctc
acggcgggctccatggaggagaagcgagaagtcttctcctatttagtgcacgtggccaaa
tgctgctggaacatgggcaactacaatgctgtcatggagttcttggccggcctcaggtca
agaaaagttttaaaaatgtggcagtttatggaccagtctgacctagagaccatgaggagc
ctgaaggatgccatggctcagcacgaatcttcctgcgagtacaagaaggtggtcacgcgg
gctctgcacatacctggctgtaaggtggttccgttctgtggggtgtttctgaaggagctc
tgtgaagtactggacggagcctccggcctcatgaagctttgcccgaggtacaattcccaa
gaagaaactctagagtttgtagccgattacagtggacaagatcatttcttacaacgagtg
ggacataatggcttaaagaattcggagaaggagtccacagtcaacagcatctttcagatc
atcaggagctgcagccgaagtctggaggccgaggaggaggacagccccagtgaaggaaac
agctccaggaaaaattccttaagggataaagcccgatggcagtttatcattggagacctg
ttagattctgaaaatgacatctttgagaaatccaaagaatgggacgctcacggatcagaa
gagccacagaaggcctttgaccatgggacagagctaatcccatggtacgtgctgtccatc
cgagccgatgtgcaccagttcctgctgcagggggccactgtcatccactatgaccaggac
acgcacctctctgcccgatgcttcctccagcttcagcctgacaacagcaccttgacctgg
acaaagcccaccactgcttccctggccagtgctaaagcaaaactcggtgtgcttagtaac
acgtctgagcctggcaaattcccgttactgggcaatgctggactaagtggcctggcagag
ggggtcttggatctgttctcagcaaaagctgtgtacatgggacaccctagcatcgatata
cacactgtgtgtgttcagaacaaactgggtagcatgtttctctcagagactggcgtgacg
ctgctctatgggctccagaccacggacaatagattattgcactttgtggcacccaggcac
acagctaagatgctcttcagtggattgctggaactcacgagagccgtgaggaagatgagg
aagttccctgaccagagacagcagtggctgcggaaacagtacgtcagcctctatcaggaa
gatggacggtacgaaggcccaactttggctcacgccgtggagttgtttggtggcaggcgg
tggagtacacgaaaccccagccccgggacatcagcaaagagtgccgagaagcccaatgtg
cagagaaacaacaccttgggcataagcactaccaagaaaaagaagaaaatccttataagg
ggtgagagcggagaggcagccgacgatgagatggccacccgaaaagccaaaatgcacaga
gagtgtcgcagccggagtggttctgaccctcaagacatgaatgaacaagaagaatcagag
gcaaatgccatcatgagccctcctaacactctgccttccagaagagcccactctttgacc
acggctgggtcccctaacttgtctgccgggacatcatctcccaacaggccagtgtcttcc
cctgtgctgtcttcttcaaacaagagcccgtccagtgcttggagcagcagcagctggcac
gggaggatcaaaggcggaatgaaaggtttccagagcttcatggtttcagacagtaacatg
agctttgttgaattcgttgagctgttcaaatcattcagcgtgaggagccgcaaggacctg
aaggacctcttcgacgtctatgccgtgccctgcaaccgagccggctccgagtcggtgcca
ctctacaccaacctaacaattgacgaaaacaccagcgatcttcagcctgacctagattta
ttgaccagaaacgtctcggatttggggttgttcattaagagtaaacagcagctgtcagac
aaccagaggcagatatctgatgccattgctgctgcaagtatcgtgacaaacggcactggg
gtcgagagcacatccttgggcgtgtttggggttggcatcctccagctcaatgacttccta
gtgaactgccaaggagaacactgcacttatgatgaaatcctcagcatcatccagaagttc
gagcctagcgttagtatgtgtcatcagggcctactgtcatttgaaggatttgcaaggttt
ctgatggataaagataatttcgcctccaaaaatgatgagtcacaggaaaacattaaagaa
ctacagctgcccctctcctactattacattgaatcttcacacaatacctacctcacaggc
caccagctcaaaggagagtcctcagtagaactctacagccaggtcctcctgcaaggctgt
aggagcgtagagctggattgttgggatggagacgacgggttgcccatcatctatcatgga
cacacgctgacaaccaagatccccttcaaggaggtggttgaagccattgaacgcagtgcc
tttgtcaactctgacctgcccatcatcatatcgattgagaaccactgctcattgcctcag
caacgaaaaatggcagaaattttcaagagtgtgtttggagaaaaactggtggctaagttc
ctgtttgagagtgatttctcagatgacccaatgcttccctcacccgaccaacttaggagg
aaagtgctccttaaaaataagaagctaaaagcccaccaaacaccagtggatatcttaaag
caaaaggctcatcagttagcatccatgcaagctcaggcttacaatggtgggaatgccaac
cccccaccggctaataacgaggaagaggaggatgaagaagacgaatatgattatgactat
gaatccctgtctgatgacaacattctggaagacagacctgaaaataaatcatgtaatgac
aagcttcagtttgagtataatgaagaaatccccaagaggataaagaaagcagataactct
gcttgcaacaaaggaaaggtttatgacatggaactgggagaagaattttatctccctcag
aataaaaaggaaagcagacagattgcaccagagctctctgaccttgtcatctattgtcaa
gcagtaaaatttccaggcctgtcaactctaaatgcatctggctctagcagaggaaaagaa
aggaaaagcaggaagtccatttttggcaacaatccgggcagaatgagccctggggagaca
gcatcgtttaacaaagcatctggaaaaagttcctgtgaaggaatgcgacaggcctgggag
gaatcttcttcccccctcaacccaaccacatccctcagcgctatcattagaactcccaaa
tgttaccatatctcctcgctgaatgaaaatgccgccaaacgtctgtgtcgcaggtattct
cagaaactgatccagcacaccgcctgtcagctgctgaggacttacccggctgccactcgc
atcgactcctccaaccccaatcccctcatgttctggctccatgggatacagctcgtggcg
ctcaactaccagacagatgatctccctttacacttaaatgctgccatgtttgaagccaac
ggtgggtgtggttatgttttgaaacccccagttctgtgggacaagaactgtcccatgtat
cagaagttctctcccttagaaagagatctggacaacatggagcctgccatctactcctta
actattgtctctggtcaaaacgtgtgcccgagtagcagcacaggaagcccgtgtatcgaa
gtcgatgtgctgggcatgcccctggacagctgccatttccgcacaaagcccatccaccgg
aacactctgaaccccatgtggaatgaacagtttctcttccgggttcactttgaagatctc
gtatttcttcgttttgccgttgtggaaaacaacagctcagctgtaactgctcagagaatc
atcccactcaaggctttaaaacgaggatatcgacatcttcagctgcgaaatctccacaac
gaagtcttggaaatctctagtttattcataaacagtaggaggatggaagaaaattcctcc
agcagcaccacgccggcctctttgatgtttaattcagaagaaagaaaatgtttgcaggct
cacagagtcacggtgcatggggtcccaggtccagagccctttactgttttctccataagt
ggaggcaccaaagcaaagcagcttctccaacaagttctgaccactgaacaagacaccaaa
cctatcatcacagactattttttgatggaagaaaaatattttatatctaaagaaaagaat
gaatgcaggaaacaaccgttccagagagtcattggtccagaggaagagattatgcagatt
ttaagcagctggtttccagaggaaggatatgttggcaggattgtcttaaaaacccagcag
gaaaacctagaagagaaaagcattgttcaagatgacaaagaggtgaccttgagctcagag
gaggagagtttctttgttcaagtgcacgatgtttctccagagcaacctcgaacggtcatc
aaagcaccacgtgtcagcaccgcacaggacgtcattcagcagaccttatgcaaagcaaag
tattcctacagcatcctgagcaatcccaacccaagtgactatgtgctcttggaagaggtg
gtaaaagacacgaccaagaagtcttccaccccaaagtcctcccagcgggtccttttggat
caggagtgtgtgtttcaagcccaaagcaagtggaaaggggcaggaaaattcatccttaag
ctaaaggagcaggtgcaggcatctcgagaagacaaaaggaaaggcatttcttttgcaagt
gaatttaagaagttcaccaagtcaactaaacaaccccgaggactcgcatcaccttctcag
gtcttggccttagaaggtgtccaaaacaaggaggagaaacctatgggcagcttgtcctcc
agtgacaccatggactatcgacaataa

DBGET integrated database retrieval system