KEGG   Felis catus (domestic cat): 101090005Help
Entry
101090005         CDS       T02385                                 

Gene name
PLCB4
Definition
phospholipase C, beta 4
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101090005 (PLCB4)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    101090005 (PLCB4)
   04310 Wnt signaling pathway
    101090005 (PLCB4)
   04020 Calcium signaling pathway
    101090005 (PLCB4)
   04070 Phosphatidylinositol signaling system
    101090005 (PLCB4)
   04022 cGMP - PKG signaling pathway
    101090005 (PLCB4)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    101090005 (PLCB4)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101090005 (PLCB4)
   04062 Chemokine signaling pathway
    101090005 (PLCB4)
  Endocrine system
   04911 Insulin secretion
    101090005 (PLCB4)
   04912 GnRH signaling pathway
    101090005 (PLCB4)
   04915 Estrogen signaling pathway
    101090005 (PLCB4)
   04921 Oxytocin signaling pathway
    101090005 (PLCB4)
   04918 Thyroid hormone synthesis
    101090005 (PLCB4)
   04919 Thyroid hormone signaling pathway
    101090005 (PLCB4)
   04916 Melanogenesis
    101090005 (PLCB4)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101090005 (PLCB4)
   04270 Vascular smooth muscle contraction
    101090005 (PLCB4)
  Digestive system
   04970 Salivary secretion
    101090005 (PLCB4)
   04971 Gastric acid secretion
    101090005 (PLCB4)
   04972 Pancreatic secretion
    101090005 (PLCB4)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101090005 (PLCB4)
  Nervous system
   04724 Glutamatergic synapse
    101090005 (PLCB4)
   04725 Cholinergic synapse
    101090005 (PLCB4)
   04728 Dopaminergic synapse
    101090005 (PLCB4)
   04726 Serotonergic synapse
    101090005 (PLCB4)
   04720 Long-term potentiation
    101090005 (PLCB4)
   04730 Long-term depression
    101090005 (PLCB4)
   04723 Retrograde endocannabinoid signaling
    101090005 (PLCB4)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101090005 (PLCB4)
  Environmental adaptation
   04713 Circadian entrainment
    101090005 (PLCB4)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    101090005 (PLCB4)
   05016 Huntington's disease
    101090005 (PLCB4)
  Infectious diseases
   05146 Amoebiasis
    101090005 (PLCB4)
   05142 Chagas disease (American trypanosomiasis)
    101090005 (PLCB4)
   05143 African trypanosomiasis
    101090005 (PLCB4)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101090005 (PLCB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
A3
AA seq 1206 aa AA seqDB search
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL
ECSLINSIRLGATPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE
VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSM
MEAGESAAPVNILEDDNEEEIESADQEEEAHPEYKFGSELSADDLGHKEAVANSVKKASD
DLEHEINKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNI
HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNRLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQ
SSSELRPTTTAALGSGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAK
EHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLISAHEQQTQQLKLS
HDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEVGSRDGPQTSNSSV
KLQNAN
NT seq 3621 nt NT seq  +upstreamnt  +downstreamnt
atggccaaaccttatgaatttaactggcaaaaggaagttccttcctttttgcaagaagga
gccgtttttgacagatatgaagaggaatcctttgtgtttgaacccaactgcctcttcaaa
gtggatgaatttggcttctttctgacctggagaagtgaaggcaaggaaggacaagttcta
gaatgctccctcatcaacagtattcgattgggagccaccccaaaggatcccaaaatcctg
gctgctcttgaagctgttggaaagtcagagaatgatctggaagggcgaatagtttgtgtc
tgcagtggcacagatctggtgaacatcagtttcacatacatggtggctgaaaatccggaa
gtaactaagcaatgggtagaaggactgagatcaatcatacacaacttcagggccaacaat
gtcagtccaatgacctgcctcaaaaaacactggatgaaattggcgtttatgaccaacaca
aatggtaaaattccagttaggagtattactagaacctttgcatcggggaaaacagaaaag
gtgatctttcaagcactcaaggagttaggtcttcccagtggaaagaatgatgaaatcgag
cctgcagcatttacttatgaaaagttctatgaactgacacaaaagatttgtcctcgaaca
gatatagaggatctttttaaaaaaatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcagcgagaccctcgactgaatgaaattttgttc
ccattttatgatgctaaaagggcaatgcagatcatcgagatgtatgagcctgatgaagat
ttgaagaaaaaaggcctcatatcaagcgatgggttttgcagatatctgatgtcagatgaa
aatgcccctgtcttcctggatcgtttagaactttaccaagaaatggaccatcctctggcc
cactacttcatcagttcttcccataacacctatctcactggccgacagtttggtggaaag
tcttccgtagaaatgtacagacaggttctcctggctggttgcaggtgtgttgaacttgac
tgttgggatggaaaaggtgaagaccaggaaccaataataactcatggaaaagcaatgtgt
acagatatcctttttaaggatgttattcaagccatcaaggaaactgcgtttgtcacatcc
gaatatcctgtaattctctcctttgaaaatcactgcagcaaatatcaacagtacaagatg
tccaaatattgcgaagatctatttggggatctcctgttgaaacaagcacttgaatcacat
ccactcgaaccaggcaggcccttaccatcccccaatgacctcaaaagaaaaatactcatc
aaaaataaacggctgaaacctgaggtcgaaaaaaaacagcttgaagctttgaaaagcatg
atggaagctggagaatctgctgccccggttaacatcttagaggatgataatgaagaggaa
atagagagtgctgaccaagaggaggaagctcaccctgaatacaaatttggaagtgaactt
tctgctgatgacttgggtcacaaggaggctgttgcaaatagtgtcaagaaggcttcagat
gaccttgaacatgaaatcaacaaaaagggcctggttactgtagaagatgaacaggcatgg
atggcatcttataaatatgtaggtgctaccactaatatccatccatatttgtctacaatg
atcaactatgcacagcctgtaaaatttcaaggtttccatgtggctgaagagcgcaatatt
cattataacatgtcttcttttaatgagtccgttggtctaggctacttgaagacacacgcg
attgaatttgtgaattacaacaaacggcaaatgagccgcatttaccccaagggaggccgg
gtcgattccagtaattacatgcctcagattttctggaacgctggctgccagatggtttcg
ctcaactatcagaccccagatttagcgatgcaattgaatcagggaaaatttgagtataat
ggatcatgcggctaccttctcaaaccagatttcatgagacggcccgatcgaacatttgat
cccttctctgaaactcctgtcgacggggttattgcagccacttgctcagtgcaggtcata
tcaggtcagtttttatcagataagaaaattggtacatatgtagaagtggatatgtatggt
ttacccactgacaccatacgtaaggaattccgaactcgcatggtgatgaacaatggactc
aatccagtttacaatgaagaatcatttgtgtttcggaaggtgatcctccctgacctggca
gtcttgagaatagctgtgtatgacgacaacaataggctgataggccagaggattcttccg
ctggatggcctccaagcaggttatcgacacatttctcttcgaaatgagggaaataaacca
ttatcactgccaacaattttctgcaatattgttcttaaaacatatgtgcctgatggattt
ggagatattgtggatgctttatcagatccaaagaaatttctttccattacggaaaagaga
gcagaccaaatgagagctatgggcattgaaactagtgacatagcagatgtgcccagtgat
acttctaagaatgacaagaaaggaaaggccaacactgccaaagcaaacgtgaccccgcag
agcagctctgagctcagaccaaccaccacagcggccctggggtctggagtggaagccaag
aaaggtatcgaacttatccctcaagtgaggatagaagatttaaagcagatgaaggcttac
ttgaagcatttaaagaaacaacagaaggagctaaattctttaaagaagaaacatgctaag
gagcacagcaccatgcagaagctgcattgcacacaagttgacaaaattgtggcacagtat
gacaaagagaagtcgacgcatgagaaaatcctagagaaggcaatgaagaagaagggggga
agtaattgtctcgaaatgaaaaaagaaacagaaattaaaattcagacactgacatcagat
cacaaatctaaggtcaaagagatagtggcccagcacacaaaggagtggtcagaaatgatt
aacacccacagtgctgaggagcaagaaatccgggacctgcacctcagccagcagtgtgag
ctcctgagaaagctactgatcagcgcccacgagcagcaaacccagcagctaaaactgtcc
catgacagggaaagcaaggaaatgcgagcacaccaggctaagatttctatggaaaatagc
aaagccatcagccaagataaatctatcaagaataaagcagagcgggaaaggagagtcagg
gagttaaatagcagcaacaccaaaaagtttctggaagaaagaaagagactcgccatgaaa
cagtccaaagaaatggatcagttgaaaaaagtccagcttgaacacctggagttcctagag
aaacagaatgagcagctattgaaatcctgccatgcagtgtcccaaacgcaaggcgaagga
gatgcagcagatggtgaagttggaagccgagatggaccgcagaccagcaacagtagtgtg
aaactccagaacgcaaactga

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