KEGG   Felis catus (domestic cat): 101090328
Entry
101090328         CDS       T02385                                 
Symbol
MAP3K1
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 1 isoform X1
  KO
K04416  mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04010  MAPK signaling pathway
fca04120  Ubiquitin mediated proteolysis
fca04530  Tight junction
fca04622  RIG-I-like receptor signaling pathway
fca04722  Neurotrophin signaling pathway
fca04912  GnRH signaling pathway
fca04935  Growth hormone synthesis, secretion and action
fca05161  Hepatitis B
fca05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:fca00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101090328 (MAP3K1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101090328 (MAP3K1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101090328 (MAP3K1)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    101090328 (MAP3K1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101090328 (MAP3K1)
   04935 Growth hormone synthesis, secretion and action
    101090328 (MAP3K1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101090328 (MAP3K1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101090328 (MAP3K1)
   05161 Hepatitis B
    101090328 (MAP3K1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    101090328 (MAP3K1)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:fca04121]
    101090328 (MAP3K1)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     101090328 (MAP3K1)
Protein kinases [BR:fca01001]
 Serine/threonine kinases: STE group
  STE11 family
   101090328 (MAP3K1)
Ubiquitin system [BR:fca04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    101090328 (MAP3K1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CEP104-like_TOG Kinase-like Pkinase_fungal zf-RING_2 SWIM ABC1 zf-ANAPC11
Other DBs
NCBI-GeneID: 101090328
NCBI-ProteinID: XP_003981022
EnsemblRapid: ENSFCTG00005013491
UniProt: M3WK29
Position
A1:124916862..124993418
AA seq 1509 aa
MAAAAGNRASSSGFPGARAASPEAGGGGGALKASSAPAAAAGLLREAGSGGRERADWRRR
QLRKVRSVELDQLPEPPLFLAASPPSSSTSPSPEPSDTAAGGSGFQPVAVPQPHGTASRG
GAQPPEPAAAPDSGAPSPAGAESGEKRTTAAEPPPAAAPAGREMENKETLKGLHKMDDRP
EERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPIKGDGSETHSLAAESPGESQAST
ASPAPKGRRSPSPGSSPAGRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYS
PEETNRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCGRGTFCIHLLF
VMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHT
LSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECR
RNREPLICPLCRSKWRSHDFYSHELSSPVDSPSSLRAAQQQTIQQPPLAGSQRRSQESNF
NLTHYGTQQIPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLAN
GESTGNSGSNGRSSPSAGATSGSSQTSISGDVVEACCNVLSMVCADPVYKVYVAALKTLR
AMLVYTPCHSLAERIKLQRLLRPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAV
GREILKAGSIGIGGVDYVLSCILGNQTESNNWQELLGRLCLMDRLLLEFPAEFYPHIAST
DVSQAEPVEVRYKKLLSLLTFALQSIDNSHSMVGKLSRRIYLSSARMVTAVPHVFSKLLE
MLNVSSSTHFTRMRRRLMAIADEVEIAEAIRLGIEDNLDGQHDSFLQASVSNSFPETTEN
SSLEHTDHVEKTGKVLCATKLSANSEDITDRLGSISVGLPSSTTMEQPKPVVQTKGRPHS
QCLNSSPLSHHSQLVFPSLSTPSSSAPSAPVGTGTDITKHRPQGFIPCKIPSASPQTQRK
FSLQFQRNCSENRDSDKLSPIFTQSRPLPSSTIHRPKPSRPTPGNTSKQGDVSKNSMTLD
LKSSTSKCDDSFGGSSNSSSAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSS
DTTVTFKSEVAVLSPEKDENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALP
IVPQLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDV
GTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFI
EWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQR
LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMA
CAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELL
KHPVFRTTW
NT seq 4530 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggggaatcgcgcctcgtcgtcgggattcccgggcgcccgggcggcg
agccccgaggcgggtggcggtggaggtgctctcaaggctagcagcgcgcccgcagcagcc
gcggggctacttcgggaggcgggcagcgggggccgcgagcgggctgactggcggcggcgg
cagctgcgcaaagtgcggagtgtggagctggaccagctgccggagccgccgctcttcctc
gccgcctcaccgccgtcctcctccacttccccgtcgccggagccctcggacacagcggcg
ggcgggagcggtttccagcctgtggccgtgccgcaaccccacggaaccgcgagccgtggc
ggcgcccaacctccggagcccgcggccgcaccggacagcggcgctccgagccccgcgggg
gccgagtccggggagaagcggacgaccgccgccgagccgcctcctgcagcggccccagcc
ggtcgcgagatggagaataaagaaactctcaaggggttgcataagatggacgatcgccca
gaagaacgaatgatcagggagaaactgaaggcaacctgtatgccagcctggaaacacgag
tggctggagagaagaaataggaggggccctgtggtggtaaaaccaatccctattaaagga
gacggttctgaaactcacagcttggcagctgagtctccaggagaaagccaggcaagcacc
gcttcaccagctcccaagggccgccgcagtccttctcctggcagctccccggcgggccgc
acagtgaaatctgaatctccaggagtgaggagaaagagagtctcccccgtaccttttcag
agcgggagaatcacaccacctagaagagccccttccccagatggcttctcaccatacagc
cctgaggagacaaaccgccgtgtaaacaaagtcatgcgggccaggctgtacttactgcaa
caaataggacccaactctttcctgattggaggagatagcccagacaataaataccgggtg
tttattgggcctcagaactgcagctgtggacgtggaacattttgtatccatctgttattt
gttatgctccgggtgtttcaactagaaccttcagacccaatgttatggagaaaaacttta
aagaattttgaggttgaaagtttgttccagaaatatcacagtaggcgtagctcaaggatc
aaagctccatctcgtaacaccatccagaagtttgtttcacgcatgtcaaattctcatacg
ttgtcatcatctagtacttctacatctagttcagaaaacagtatcaaagatgaggaggaa
cagatgtgtcctatttgcttgttgggcatgcttgatgaagaaagtcttactgtgtgtgaa
gacggctgcaggaacaagctgcatcaccactgcatgtcaatctgggcagaagaatgtaga
agaaatagagaacctttaatatgtcccctttgtaggtctaaatggagatctcacgatttc
tacagccatgagttgtcaagccctgtggattccccttcttccctgcgagctgcacagcag
caaaccatacagcagccgcctttggctggatcacaacgaaggagtcaggagagcaacttt
aaccttactcattatggaactcagcagattcctcctgcttacaaagatttagctgagcca
tggattcaggtatttggaatggaactcgttggctgcttattttctagaaactggaatgta
agagagatggctctcaggcgtctttcccatgatgttagtggggctctgctattggcaaat
ggggagagcactggaaattctgggagcaatggtagaagcagcccgagtgctggagccacc
agtgggtcttcccagaccagtatctcaggagacgtggtagaggcatgctgcaacgtttta
tcaatggtctgtgctgaccctgtctacaaagtgtacgttgctgctttaaaaacattgaga
gccatgctggtatatactccttgccatagtttggcagaaagaatcaaactgcagagactt
ctccggccagttgtagacaccatcctagtcaagtgtgcagatgccaatagtcgcacaagt
cagctgtctatatcaaccctgttggaattgtgcaaaggccaagcaggagagttggcagtt
ggcagagaaatacttaaagctggatccattggtattggtggtgttgattatgtcttaagt
tgtattcttggaaaccaaactgaatcaaacaactggcaagaacttctgggccgcctttgt
cttatggacagactgctgttggaatttcctgctgaattttaccctcatatcgccagtact
gatgtttcacaagctgagcctgttgaagtcaggtataaaaagctgctgtccctcttaacc
tttgctttgcagtccattgataattcccactcaatggttggcaaactctcccgaaggatc
tatttgagttctgcaagaatggttactgcagtaccccatgtattttcaaaactgttagaa
atgctgaatgtttccagttccactcattttaccaggatgcgtcgtcgtctgatggctatt
gcagatgaggtggaaatcgctgaggccatccggctgggcatagaagacaatttggatggt
caacatgacagctttttgcaggcatctgtctctaacagctttcctgaaaccacagagaac
agctcccttgagcacacagaccatgtagagaaaactggaaaagtactgtgtgccacaaaa
ctgagtgccaattcagaagacattactgacagactgggcagcatttcagtaggacttcct
agttcaacaacaatggagcaaccaaagccagtggttcaaactaaaggcagaccccacagt
cagtgtttgaactcctctcctttatctcatcattcccaattagtgtttccatccttgtca
actccttcttcatctgccccatctgcaccagttggtaccggaacagatatcactaagcat
agacctcagggattcattccctgcaaaataccttctgcatctcctcaaacacagcgtaag
ttttctctacagttccagagaaactgttccgaaaacagagactcagataaactttccccc
atctttactcagtcaagacccctgccttctagtactatacacaggccaaagccgtctcga
cctaccccaggtaatacaagtaaacaaggagatgtctcaaagaatagcatgacacttgac
ctgaaaagtagtacttccaaatgtgatgacagctttggtggcagcagcaatagcagtagt
gctgttatacccagtgatgagacagtattcaccccagtagaagagaaatgcagattagac
gtcaatacagaactcaattccagcattgaggaccttcttgaagcatctatgccttcaagt
gacacaacagtaacttttaagtcagaagttgctgtcctgtctcctgaaaaggatgaaaat
gatgatacctacaaagatgatgtgaatcataatcagaagtgcaaagaaaagatggaagct
gaagaagaagaagctttagcaattgccatggcaatgtcagcgtctcaggatgccctcccc
atagttcctcaactacaggttgaaaatggagaggatatcatcattattcaacaggataca
cccgaaactctaccaggacataccaaagcaaagcaaccttacagagaagacactgaatgg
ctaaaaggtcagcagataggccttggagcattttcttcttgttatcaggctcaagatgtg
ggaactggaactttaatggctgttaaacaggtgacatatgtcagaaatacatcttctgag
caagaagaagtagtggaagcattaagagaagagatcagaatgatgagccatttgaatcat
cccaacatcattaggatgttgggagccacatgtgagaagagcaattataatctcttcatc
gaatggatggcagggggatctgtggctcatttgctcagtaaatatggagccttcaaagag
tcagtagttattaactatactgaacaattacttcgtggcctttcatatctccatgaaaac
cagatcattcacagagatgtcaaaggtgccaatttgctcattgacagcacaggtcagaga
ctgagaattgcagattttggagctgcagccaggttggcatcaaaaggaactggtgcagga
gagtttcagggacagttattggggacaattgcatttatggcacctgaggtactaagaggt
cagcaatatggtaggagctgtgatgtatggagtgttggctgtgctattatagaaatggct
tgtgctaaaccaccctggaatgcagaaaaacactccaatcatcttgctttgatatttaag
attgcaagtgcaactactgctccatcgatcccttcacatttgtctcctggtttacgggat
gtggctcttcggtgtttggaacttcaacctcaggatagacctccgtcaagagagctactg
aagcatccagtcttccgtactacatggtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (9)   
   Pfam (9)   
All databases (71)   

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