KEGG   Felis catus (domestic cat): 101090494Help
Entry
101090494         CDS       T02385                                 

Gene name
PRKACA
Definition
protein kinase, cAMP-dependent, catalytic, alpha
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
fca  Felis catus (domestic cat)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Module
cAMP signaling
Brite
KEGG Orthology (KO) [BR:fca00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101090494 (PRKACA)
   04010 MAPK signaling pathway
    101090494 (PRKACA)
   04310 Wnt signaling pathway
    101090494 (PRKACA)
   04340 Hedgehog signaling pathway
    101090494 (PRKACA)
   04020 Calcium signaling pathway
    101090494 (PRKACA)
   04024 cAMP signaling pathway
    101090494 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    101090494 (PRKACA)
   04210 Apoptosis
    101090494 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    101090494 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101090494 (PRKACA)
   04062 Chemokine signaling pathway
    101090494 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    101090494 (PRKACA)
   04910 Insulin signaling pathway
    101090494 (PRKACA)
   04912 GnRH signaling pathway
    101090494 (PRKACA)
   04913 Ovarian Steroidogenesis
    101090494 (PRKACA)
   04915 Estrogen signaling pathway
    101090494 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    101090494 (PRKACA)
   04921 Oxytocin signaling pathway
    101090494 (PRKACA)
   04918 Thyroid hormone synthesis
    101090494 (PRKACA)
   04919 Thyroid hormone signaling pathway
    101090494 (PRKACA)
   04916 Melanogenesis
    101090494 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101090494 (PRKACA)
   04270 Vascular smooth muscle contraction
    101090494 (PRKACA)
  Digestive system
   04970 Salivary secretion
    101090494 (PRKACA)
   04971 Gastric acid secretion
    101090494 (PRKACA)
   04976 Bile secretion
    101090494 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    101090494 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101090494 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    101090494 (PRKACA)
   04727 GABAergic synapse
    101090494 (PRKACA)
   04725 Cholinergic synapse
    101090494 (PRKACA)
   04728 Dopaminergic synapse
    101090494 (PRKACA)
   04726 Serotonergic synapse
    101090494 (PRKACA)
   04720 Long-term potentiation
    101090494 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    101090494 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    101090494 (PRKACA)
   04742 Taste transduction
    101090494 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    101090494 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    101090494 (PRKACA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101090494 (PRKACA)
   05205 Proteoglycans in cancer
    101090494 (PRKACA)
   05203 Viral carcinogenesis
    101090494 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    101090494 (PRKACA)
   05020 Prion diseases
    101090494 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    101090494 (PRKACA)
   05031 Amphetamine addiction
    101090494 (PRKACA)
   05032 Morphine addiction
    101090494 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    101090494 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    101090494 (PRKACA)
   05169 Epstein-Barr virus infection
    101090494 (PRKACA)
   05146 Amoebiasis
    101090494 (PRKACA)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     101090494 (PRKACA)
Protein kinases [BR:fca01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   101090494 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
A2
AA seq 344 aa AA seqDB search
MMASNPNDVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETG
NHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGG
EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG
FAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQI
YEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIY
QRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1035 nt NT seq  +upstreamnt  +downstreamnt
atgatggcttccaaccccaacgatgtgaaagagttcttagccaaagccaaagaagatttt
cttaaaaaatgggaaaatcctgctcagaatacagcccatttggatcagtttgaacgaatc
aagaccctcggcacgggctcctttgggcgggtgatgctggtaaagcacaaggagaccggg
aaccactttgccatgaagatcctcgacaaacagaaggtggtgaagctgaaacagattgag
cacaccctgaacgaaaagcgcatcctgcaagcggtcaactttccgttcctcgtcaaactc
gagttctccttcaaggacaactcgaacttatacatggtcatggagtacgtgcctggcggg
gagatgttctcacacctgcggcggattggaaggttcagtgaacctcacgcgcgcttttat
gcggcccagatcgtcctgaccttcgagtacctgcactcacttgacctcatctaccgggac
ctgaagccggagaacctcctcattgaccagcagggctacattcaggtgacagacttcggt
tttgccaagcgtgtaaaaggccgcacctggaccttatgcgggacccctgagtacctggcc
ccggagatcatcctgagcaaaggctacaacaaggccgtggactggtgggccctaggggtg
ctcatctacgagatggccgccggctaccctcctttcttcgctgaccagcccatccagatc
tatgagaagattgtctctgggaaggtgcggttcccatcccacttcagctccgacctgaag
gatctgctgcggaacctactgcaggtggacctcaccaaacgctttgggaacctcaagaat
ggagtcaacgatatcaagaaccacaaatggtttgccacaactgactggatcgccatctac
cagaggaaggtggaagctcccttcataccaaagtttaaaggccctggggacacgagtaat
ttcgacgactatgaggaggaagagatccgagtctccatcaatgagaagtgtggcaaggag
tttactgagttttag

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