KEGG   Felis catus (domestic cat): 101090942Help
Entry
101090942         CDS       T02385                                 

Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Apelin signaling pathway
Gap junction
Platelet activation
NOD-like receptor signaling pathway
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101090942
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    101090942
   04310 Wnt signaling pathway
    101090942
   04371 Apelin signaling pathway
    101090942
   04020 Calcium signaling pathway
    101090942
   04070 Phosphatidylinositol signaling system
    101090942
   04072 Phospholipase D signaling pathway
    101090942
   04071 Sphingolipid signaling pathway
    101090942
   04022 cGMP - PKG signaling pathway
    101090942
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    101090942
 Organismal Systems
  Immune system
   04611 Platelet activation
    101090942
   04621 NOD-like receptor signaling pathway
    101090942
   04062 Chemokine signaling pathway
    101090942
  Endocrine system
   04911 Insulin secretion
    101090942
   04922 Glucagon signaling pathway
    101090942
   04912 GnRH signaling pathway
    101090942
   04915 Estrogen signaling pathway
    101090942
   04921 Oxytocin signaling pathway
    101090942
   04926 Relaxin signaling pathway
    101090942
   04918 Thyroid hormone synthesis
    101090942
   04919 Thyroid hormone signaling pathway
    101090942
   04916 Melanogenesis
    101090942
   04924 Renin secretion
    101090942
   04925 Aldosterone synthesis and secretion
    101090942
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101090942
   04270 Vascular smooth muscle contraction
    101090942
  Digestive system
   04970 Salivary secretion
    101090942
   04971 Gastric acid secretion
    101090942
   04972 Pancreatic secretion
    101090942
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101090942
  Nervous system
   04724 Glutamatergic synapse
    101090942
   04725 Cholinergic synapse
    101090942
   04728 Dopaminergic synapse
    101090942
   04726 Serotonergic synapse
    101090942
   04720 Long-term potentiation
    101090942
   04730 Long-term depression
    101090942
   04723 Retrograde endocannabinoid signaling
    101090942
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101090942
  Environmental adaptation
   04713 Circadian entrainment
    101090942
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101090942
  Neurodegenerative diseases
   05010 Alzheimer's disease
    101090942
   05016 Huntington's disease
    101090942
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    101090942
  Infectious diseases
   05146 Amoebiasis
    101090942
   05142 Chagas disease (American trypanosomiasis)
    101090942
   05143 African trypanosomiasis
    101090942
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101090942
Membrane trafficking [BR:fca04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    101090942
 Endocytosis
  Macropinocytosis
   Phospholipase C
    101090942
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
B3
AA seq 688 aa AA seqDB search
MSLLNPVLLPPKVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEIEFLD
ITSIRDTRFGKFAKIPKSQKLRDVFNMDFPENNFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGQNWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSSCHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDSRLNSLLFPPARPDQVRGLIDKYEPSAINVQRGQLSPEGMVWFLCGPEN
SVLAQDKLLLYQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRTMFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPASPSKEPGGE
AEGDCPPSASVGEGTAWAGEEGAEPEEEEVEEEEESGSLNEEEIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSR
IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMR
RPDKQFNPFSVDRIDVVVATTLSITARP
NT seq 2067 nt NT seq  +upstreamnt  +downstreamnt
atgtctctgctcaaccctgtcctgctgccccccaaggtgaaggcttatctgagccaaggg
gagcgcttcatcaaatgggacgatgaaaccacaatagcctccccggttatcctccgcgtg
gatcccaagggctactacttatattggacatatcagagtaaggagatagagtttctggat
atcaccagcatcagggatactcgctttgggaagtttgccaagatacccaagagccagaag
ctccgggatgtcttcaacatggactttcctgagaacaacttcctgctaaagacgctcact
gtggtgtctggcccggacatggtggacctcaccttccacaactttgtctcctacaaggag
aacgtaggccagaactgggctgaagatgtcctggctctggtcaagcacccgctgacagcc
aatgcctctcgcagcaccttcctggacaaaatcctggtaaagctcaagatgcagctcaat
cccgaagggaagattcctgtgaagaattttttccagatgtttcctgctgaccgcaagcgg
gtggaagctgccctcagctcctgccacctccccaaaggcaagaatgatgccatcaatcct
gaggacttcccagaatccgtctacaagagtttcctcatgagcctctgtcctcggccagaa
atagatgagatcttcacttcctaccacgccaaggccaagccctacatgaccaaggaacac
ctgaccaaattcatcaaccagaaacagagggactcccgcctcaactctttgctgtttccg
cccgcccggcctgaccaagtgcggggcctcatcgacaagtacgagcccagcgcaatcaac
gtgcagaggggccagctgtcacctgagggcatggtgtggtttctctgtgggccagagaac
agtgtgctggcccaggacaagctgctactctaccaagacatgacacagccactcaaccat
tacttcatcaactcctcacacaacacctacctgacagctggccagttctctggcctttcc
tcggcagagatgtaccgccaggtgctgctggctggctgtcgctgcgtggagctggactgc
tggaagggcaggccccctgacgaggagcccatcatcacccacggctttaccatgaccaca
gacatctatttcaaggaagcaattgaagccattgcagaaagtgcttttaagacctccccc
tatcctgtcatcctgtcatttgaaaaccatgtggactcaccccgccaacaggccaagatg
gctgagtattgccggacgatgtttggggacatgctactcacagagcccctggaaaagttc
ccactgaaaccaggcatccccctgcccagccccgaggatctccgaggcaagatcctcatc
aagaacaaaaagaaccagttttctggcccagcatcccccagcaaggagccgggtggggag
gcggagggcgactgcccacccagtgcctctgtgggtgagggcacagcgtgggctggtgaa
gaaggagcagagccggaggaggaagaggtggaagaggaggaggagtcgggaagcctgaat
gaggaagagatcaagaagatgcagtcggacgagggcacagcgggcctggaggtgacggct
tatgaggagatgtccagcctagtgaattacattcaacccaccaagttcatctcctttgag
ttctctgcccagaagaaccgaagttatgtcatctcctccttcacagagctcaaggcttac
gacctgctctccaaggcctcagtgcagtttgtggactacaacaagcgccagatgagccgc
atttaccctaagggcacccgcatggactcctccaactacatgccccagatgttctggaat
gctggttgccagatggttgccctcaacttccagacgatggacctgcccatgcagcagaac
atggcgctgtttgagttcaatgggcagagtggctacctcctcaagcatgagttcatgcgc
cggccagacaagcagttcaaccccttctcagtggaccgcatcgatgtggtggtagccacc
accctctccattacggcaaggccctga

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