KEGG   Felis catus (domestic cat): 101090942Help
Entry
101090942         CDS       T02385                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101090942 (PLCB2)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    101090942 (PLCB2)
   04310 Wnt signaling pathway
    101090942 (PLCB2)
   04020 Calcium signaling pathway
    101090942 (PLCB2)
   04070 Phosphatidylinositol signaling system
    101090942 (PLCB2)
   04022 cGMP - PKG signaling pathway
    101090942 (PLCB2)
 Cellular Processes
  Cell communication
   04540 Gap junction
    101090942 (PLCB2)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101090942 (PLCB2)
   04062 Chemokine signaling pathway
    101090942 (PLCB2)
  Endocrine system
   04911 Insulin secretion
    101090942 (PLCB2)
   04912 GnRH signaling pathway
    101090942 (PLCB2)
   04915 Estrogen signaling pathway
    101090942 (PLCB2)
   04921 Oxytocin signaling pathway
    101090942 (PLCB2)
   04918 Thyroid hormone synthesis
    101090942 (PLCB2)
   04919 Thyroid hormone signaling pathway
    101090942 (PLCB2)
   04916 Melanogenesis
    101090942 (PLCB2)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101090942 (PLCB2)
   04270 Vascular smooth muscle contraction
    101090942 (PLCB2)
  Digestive system
   04970 Salivary secretion
    101090942 (PLCB2)
   04971 Gastric acid secretion
    101090942 (PLCB2)
   04972 Pancreatic secretion
    101090942 (PLCB2)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101090942 (PLCB2)
  Nervous system
   04724 Glutamatergic synapse
    101090942 (PLCB2)
   04725 Cholinergic synapse
    101090942 (PLCB2)
   04728 Dopaminergic synapse
    101090942 (PLCB2)
   04726 Serotonergic synapse
    101090942 (PLCB2)
   04720 Long-term potentiation
    101090942 (PLCB2)
   04730 Long-term depression
    101090942 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    101090942 (PLCB2)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101090942 (PLCB2)
  Environmental adaptation
   04713 Circadian entrainment
    101090942 (PLCB2)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    101090942 (PLCB2)
   05016 Huntington's disease
    101090942 (PLCB2)
  Infectious diseases
   05146 Amoebiasis
    101090942 (PLCB2)
   05142 Chagas disease (American trypanosomiasis)
    101090942 (PLCB2)
   05143 African trypanosomiasis
    101090942 (PLCB2)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101090942 (PLCB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
B3
AA seq 699 aa AA seqDB search
MSLLNPVLLPPKVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEIEFLD
ITSIRDTRFGKFAKIPKSQKLRDVFNMDFPENNFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGQNWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSSCHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDSRLNSLLFPPARPDQVRGLIDKYEPSAINVQRGQLSPEGMVWFLCGPEN
SVLAQDKLLLYQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRTMFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPASPSKEPGGE
AEGDCPPSASVGEGTAWAGEEGAEPEEEEVEEEEESGSLNEEEIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSR
IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMR
RPDKQFNPFSVDRIDVVVATTLSITARPEVDKWPGGLGT
NT seq 2100 nt NT seq  +upstreamnt  +downstreamnt
atgtctctgctcaaccctgtcctgctgccccccaaggtgaaggcttatctgagccaaggg
gagcgcttcatcaaatgggacgatgaaaccacaatagcctccccggttatcctccgcgtg
gatcccaagggctactacttatattggacatatcagagtaaggagatagagtttctggat
atcaccagcatcagggatactcgctttgggaagtttgccaagatacccaagagccagaag
ctccgggatgtcttcaacatggactttcctgagaacaacttcctgctaaagacgctcact
gtggtgtctggcccggacatggtggacctcaccttccacaactttgtctcctacaaggag
aacgtaggccagaactgggctgaagatgtcctggctctggtcaagcacccgctgacagcc
aatgcctctcgcagcaccttcctggacaaaatcctggtaaagctcaagatgcagctcaat
cccgaagggaagattcctgtgaagaattttttccagatgtttcctgctgaccgcaagcgg
gtggaagctgccctcagctcctgccacctccccaaaggcaagaatgatgccatcaatcct
gaggacttcccagaatccgtctacaagagtttcctcatgagcctctgtcctcggccagaa
atagatgagatcttcacttcctaccacgccaaggccaagccctacatgaccaaggaacac
ctgaccaaattcatcaaccagaaacagagggactcccgcctcaactctttgctgtttccg
cccgcccggcctgaccaagtgcggggcctcatcgacaagtacgagcccagcgcaatcaac
gtgcagaggggccagctgtcacctgagggcatggtgtggtttctctgtgggccagagaac
agtgtgctggcccaggacaagctgctactctaccaagacatgacacagccactcaaccat
tacttcatcaactcctcacacaacacctacctgacagctggccagttctctggcctttcc
tcggcagagatgtaccgccaggtgctgctggctggctgtcgctgcgtggagctggactgc
tggaagggcaggccccctgacgaggagcccatcatcacccacggctttaccatgaccaca
gacatctatttcaaggaagcaattgaagccattgcagaaagtgcttttaagacctccccc
tatcctgtcatcctgtcatttgaaaaccatgtggactcaccccgccaacaggccaagatg
gctgagtattgccggacgatgtttggggacatgctactcacagagcccctggaaaagttc
ccactgaaaccaggcatccccctgcccagccccgaggatctccgaggcaagatcctcatc
aagaacaaaaagaaccagttttctggcccagcatcccccagcaaggagccgggtggggag
gcggagggcgactgcccacccagtgcctctgtgggtgagggcacagcgtgggctggtgaa
gaaggagcagagccggaggaggaagaggtggaagaggaggaggagtcgggaagcctgaat
gaggaagagatcaagaagatgcagtcggacgagggcacagcgggcctggaggtgacggct
tatgaggagatgtccagcctagtgaattacattcaacccaccaagttcatctcctttgag
ttctctgcccagaagaaccgaagttatgtcatctcctccttcacagagctcaaggcttac
gacctgctctccaaggcctcagtgcagtttgtggactacaacaagcgccagatgagccgc
atttaccctaagggcacccgcatggactcctccaactacatgccccagatgttctggaat
gctggttgccagatggttgccctcaacttccagacgatggacctgcccatgcagcagaac
atggcgctgtttgagttcaatgggcagagtggctacctcctcaagcatgagttcatgcgc
cggccagacaagcagttcaaccccttctcagtggaccgcatcgatgtggtggtagccacc
accctctccattacggcaaggcctgaggtggacaagtggccgggagggctggggacttga

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