KEGG   Felis catus (domestic cat): 101092262Help
Entry
101092262         CDS       T02385                                 

Gene name
PLCB1
Definition
phospholipase C, beta 1 (phosphoinositide-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:fca00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:fca04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:fca04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:fca04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:fca04070]
Cellular Processes; Cell communication; Gap junction [PATH:fca04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:fca04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:fca04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:fca04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:fca04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:fca04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:fca04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:fca04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:fca04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:fca04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:fca04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:fca04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:fca04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:fca04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:fca04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:fca04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:fca04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:fca04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:fca04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:fca04720]
Organismal Systems; Nervous system; Long-term depression [PATH:fca04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:fca04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:fca04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:fca04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:fca05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:fca05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:fca05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:fca05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:fca05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
A3
AA seq 1252 aa AA seqDB search
MALLWEPTRQRTQRSSRQVVADAKLQRLAPEWRRQKIIKNTSDVEIRSDARTVLERSPVR
HYLKKDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRE
LLDVGNIGRLEHRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR
DAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFT
PEVYRVFLNNLCPRPXXXXXXXHFFSQFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYP
PLKQEQVQVLIEKYEPNDSLAKKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSH
YFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTT
EISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKY
PLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGA
GEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFETSKKRNRS
FEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVAL
NFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIIS
GQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLAC
LRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYA
DVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSETRTTPAENGV
NHTTSLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKPFVKLQK
KHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKTAKKDSKKKSEPSSPD
HGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTD
VAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQ
EVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMDLEQEYQDKFKRLPLEILEF
VQEAMKGKISEDSNHSSAPPSLASDPGKLNHRPPSSEELEGDNPGKEFDTPL
NT seq 3759 nt NT seq  +upstreamnt  +downstreamnt
atggcacttttatgggagcccacgcggcagaggacacagcggtccagccgacaggtggtc
gctgatgccaaacttcagcgcctggctccggagtggaggagacagaaaattatcaagaac
accagtgatgtagagattagaagtgatgcaaggacagtattggagaggtcaccagtcaga
cactacctgaagaaggactccactattgtcactccaattattttgaggactgaccctcag
ggatttttcttttactggacagatcaaaataaggagacggagctgttagatctcagcctt
gtcaaggatgccagatgtgggaaacatgccaaagctcccaaggaccccaaattacgtgaa
cttttggatgtggggaacatcggacgcttggagcatcgcatgataacggtggtgtacggg
cctgacttagttaacatctcccatttgaatctcgtggctttccaagaggaagtggccaag
gaatggacaaatgaggttttcagtttggcaacaaacctgctggcccaaaatatgtccaga
gacgcatttctggaaaaagcctatacgaagcttaagctgcaagtcactccagaagggcgc
attcctctcaaaaacatataccgcttgttctcagcagaccggaagcgagttgaaactgct
ttagaggcttgtagtcttccatcttcaaggaatgattcaatacctcaagaagatttcact
ccagaagtgtacagagttttcctgaacaacctttgccctcgacctgnnnnnnnnnnnnnn
nnnnnncactttttctcgcaatttggtgccaaaagcaaaccataccttacagttgatcag
atgatggattttatcaacctgaagcagcgagatcctcggctaaatgaaatactttaccca
cctttaaagcaagagcaagtccaagtactgattgagaagtatgagcccaacgatagcctt
gccaaaaaaggacagatatcagtggatggctttatgcgctatctgagtggagaagaaaat
ggagtcgtttcgcctgagaaactggatttgaatgaagatatgtctcagcccctttctcac
tatttcatcaattcctcacacaacacctacctcacagctggccagctggctggaaattcc
tctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtggagttggactgc
tggaaaggacggactgcagaagaggaaccagtcatcacccatgggttcaccatgacaact
gaaatatccttcaaggaagtgatagaagcaattgctgagtgtgcatttaagacgtcacct
tttccaattctgctttcatttgagaaccacgtagattccccaaagcagcaagccaagatg
gcagagtattgccgactgatctttggagatgctcttctcatggaaccactggaaaaatac
ccactggaatctggagttcctcttccaagccctatggatttaatgtacaaaattttggtg
aaaaataagaagaaatcgcataagtcatcagaaggaagtggcaaaaagaagctctcagaa
caagcctccaacacgtacagtgactcctccagcgtgtttgagccctcatctccaggagcc
ggggaagctgatactgagagtgacgacgatgacgatgatgacgactgtaaaaaatcttca
atggatgagggtactgctggcagtgaggccatggccacagaagagatgtctaacctggtg
aactatattcagccagtcaagtttgagtcctttgaaacttcaaaaaaaagaaatagaagt
tttgaaatgtcttccttcgtggaaaccaaaggactcgagcaactgacaaagtctccagtg
gaatttgtagaatataacaaaatgcagctcagcaggatatatccaaaaggaacccgtgtg
gattcatccaactacatgcctcagctcttctggaatgctggttgccaaatggttgcactt
aattttcaaactgtggacctggctatgcaaataaatatggggatgtatgaatacaatggg
aaaagtggctacagattaaagccagagttcatgaggagacccgacaagcactttgatcca
ttcaccgaaggcatcgtagatgggatagtggccaacactttatctgtgaagattatttca
ggtcagtttctttctgataagaaagttgggacctatgtggaagtggatatgtttggtttg
cctgtggacacaaggaggaaggcatttaagaccaaaacatcacaaggaaatgctgtaaat
cctgtctgggaagaagagcccattgtgttcaaaaaggtggttcttccttctctggcctgt
ttgaggatagcagtttatgaagaaggaggtaaatttatcggtcaccggatcttgcctgta
caggcaattcggccaggctatcactacatctgtctgcggaatgagaggaaccagcctctg
atgctcccagctgtctttgtctacatagaggtgaaagactatgtcccagatacatatgca
gatgtgattgaagctttgtcaaatccaatacgatatgtgaatctgatggagcagagagca
aagcaactggctgctctgacactggaagatgaagaagaagtaaagaaagaggctgatcct
ggggaaacaccatcagaagctccaagtgaaaccaggacaactccagcagaaaacggagtg
aatcacactacatccctggcacccaaaccaccctcccaggctccccacagccaaccagct
ccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagtgttttaacagaa
gtggaagcacagactatcgaagagctaaagcaacagaaaccgtttgtgaaacttcaaaag
aagcactacaaagaaatgaaagacctggtgaaaagacaccacaagaaaaccactgacctt
atcaaagaacacactacaaaatataatgaaattcagaatgactacttgagaaggagggca
gctttggaaaagacagccaaaaaggatagtaagaaaaaatcagaacccagcagtcctgac
catggttcatcaacaattgagcaagatcttgctgccctagatgctgaaatgacccaaaag
ttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcgacaagaacagtat
tacagtgagaaataccagaagcgagaacatattaaactgcttattcagaaattgacggat
gttgccgaagaatgtcagaacaatcagctgaagaagctcaaagaaatctgtgagaaggag
aagaaggaattaaagaagaaaatggataaaaaaaggcaggagaagatcacagaagctaaa
tccaaagacaaaagtcaaatggaagaggaaaagacagagatgatccggtcatacatccag
gaggtggtacagtacatcaagaggttagaagaggcacaaagtaaacggcaagaaaaactt
gtagagaaacacaaggagatccgtcagcagatcctggatgaaaagcccaagctgcagatg
gatctggagcaagagtaccaagacaagttcaaaagactgcccctggagatcttggagttc
gtgcaggaagccatgaaagggaagatcagtgaagacagcaatcacagttctgcccctccc
tccctggcctcagaccctggaaaactgaaccacaggcctccttccagtgaggagctagaa
ggggacaacccaggaaaagagtttgatactcctctgtga

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