KEGG   Felis catus (domestic cat): 101092262Help
Entry
101092262         CDS       T02385                                 

Gene name
PLCB1
Definition
(RefSeq) phospholipase C beta 1
  KO
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Apelin signaling pathway
Gap junction
Platelet activation
NOD-like receptor signaling pathway
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101092262 (PLCB1)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    101092262 (PLCB1)
   04310 Wnt signaling pathway
    101092262 (PLCB1)
   04371 Apelin signaling pathway
    101092262 (PLCB1)
   04020 Calcium signaling pathway
    101092262 (PLCB1)
   04070 Phosphatidylinositol signaling system
    101092262 (PLCB1)
   04072 Phospholipase D signaling pathway
    101092262 (PLCB1)
   04071 Sphingolipid signaling pathway
    101092262 (PLCB1)
   04022 cGMP - PKG signaling pathway
    101092262 (PLCB1)
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    101092262 (PLCB1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101092262 (PLCB1)
   04621 NOD-like receptor signaling pathway
    101092262 (PLCB1)
   04062 Chemokine signaling pathway
    101092262 (PLCB1)
  Endocrine system
   04911 Insulin secretion
    101092262 (PLCB1)
   04922 Glucagon signaling pathway
    101092262 (PLCB1)
   04912 GnRH signaling pathway
    101092262 (PLCB1)
   04915 Estrogen signaling pathway
    101092262 (PLCB1)
   04921 Oxytocin signaling pathway
    101092262 (PLCB1)
   04926 Relaxin signaling pathway
    101092262 (PLCB1)
   04918 Thyroid hormone synthesis
    101092262 (PLCB1)
   04919 Thyroid hormone signaling pathway
    101092262 (PLCB1)
   04916 Melanogenesis
    101092262 (PLCB1)
   04924 Renin secretion
    101092262 (PLCB1)
   04925 Aldosterone synthesis and secretion
    101092262 (PLCB1)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101092262 (PLCB1)
   04270 Vascular smooth muscle contraction
    101092262 (PLCB1)
  Digestive system
   04970 Salivary secretion
    101092262 (PLCB1)
   04971 Gastric acid secretion
    101092262 (PLCB1)
   04972 Pancreatic secretion
    101092262 (PLCB1)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101092262 (PLCB1)
  Nervous system
   04724 Glutamatergic synapse
    101092262 (PLCB1)
   04725 Cholinergic synapse
    101092262 (PLCB1)
   04728 Dopaminergic synapse
    101092262 (PLCB1)
   04726 Serotonergic synapse
    101092262 (PLCB1)
   04720 Long-term potentiation
    101092262 (PLCB1)
   04730 Long-term depression
    101092262 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    101092262 (PLCB1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101092262 (PLCB1)
  Environmental adaptation
   04713 Circadian entrainment
    101092262 (PLCB1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101092262 (PLCB1)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    101092262 (PLCB1)
   05016 Huntington's disease
    101092262 (PLCB1)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    101092262 (PLCB1)
  Infectious diseases
   05146 Amoebiasis
    101092262 (PLCB1)
   05142 Chagas disease (American trypanosomiasis)
    101092262 (PLCB1)
   05143 African trypanosomiasis
    101092262 (PLCB1)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101092262 (PLCB1)
Membrane trafficking [BR:fca04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    101092262 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    101092262 (PLCB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
A3
AA seq 1248 aa AA seqDB search
MALLWEPTRQRTQRSSRQVVADAKLQRLAPEWRRQKIIKNTSDVEIRSDARTVLERSPVR
HYLKKDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRE
LLDVGNIGRLEHRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR
DAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFT
PEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQ
EQVQVLIEKYEPNDSLAKKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFIN
SSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISF
KEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLES
GVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEAD
TESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFETSKKRNRSFEMS
SFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQT
VDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFL
SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIA
VYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIE
ALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSETRTTPAENGVNHTT
SLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKPFVKLQKKHYK
EMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKTAKKDSKKKSEPSSPDHGSS
TIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEE
CQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQ
YIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMDLEQEYQDKFKRLPLEILEFVQEA
MKGKISEDSNHSSAPPSLASDPGKLNHRPPSSEELEGDNPGKEFDTPL
NT seq 3747 nt NT seq  +upstreamnt  +downstreamnt
atggcacttttatgggagcccacgcggcagaggacacagcggtccagccgacaggtggtc
gctgatgccaaacttcagcgcctggctccggagtggaggagacagaaaattatcaagaac
accagtgatgtagagattagaagtgatgcaaggacagtattggagaggtcaccagtcaga
cactacctgaagaaggactccactattgtcactccaattattttgaggactgaccctcag
ggatttttcttttactggacagatcaaaataaggagacggagctgttagatctcagcctt
gtcaaggatgccagatgtgggaaacatgccaaagctcccaaggaccccaaattacgtgaa
cttttggatgtggggaacatcggacgcttggagcatcgcatgataacggtggtgtacggg
cctgacttagttaacatctcccatttgaatctcgtggctttccaagaggaagtggccaag
gaatggacaaatgaggttttcagtttggcaacaaacctgctggcccaaaatatgtccaga
gacgcatttctggaaaaagcctatacgaagcttaagctgcaagtcactccagaagggcgc
attcctctcaaaaacatataccgcttgttctcagcagaccggaagcgagttgaaactgct
ttagaggcttgtagtcttccatcttcaaggaatgattcaatacctcaagaagatttcact
ccagaagtgtacagagttttcctgaacaacctttgccctcgacctgaaattgataacatc
ttttctgaatttggtgccaaaagcaaaccataccttacagttgatcagatgatggatttt
atcaacctgaagcagcgagatcctcggctaaatgaaatactttacccacctttaaagcaa
gagcaagtccaagtactgattgagaagtatgagcccaacgatagccttgccaaaaaagga
cagatatcagtggatggctttatgcgctatctgagtggagaagaaaatggagtcgtttcg
cctgagaaactggatttgaatgaagatatgtctcagcccctttctcactatttcatcaat
tcctcacacaacacctacctcacagctggccagctggctggaaattcctctgttgagatg
tatcgccaagtgctcctgtctggttgtcgctgtgtggagttggactgctggaaaggacgg
actgcagaagaggaaccagtcatcacccatgggttcaccatgacaactgaaatatccttc
aaggaagtgatagaagcaattgctgagtgtgcatttaagacgtcaccttttccaattctg
ctttcatttgagaaccacgtagattccccaaagcagcaagccaagatggcagagtattgc
cgactgatctttggagatgctcttctcatggaaccactggaaaaatacccactggaatct
ggagttcctcttccaagccctatggatttaatgtacaaaattttggtgaaaaataagaag
aaatcgcataagtcatcagaaggaagtggcaaaaagaagctctcagaacaagcctccaac
acgtacagtgactcctccagcgtgtttgagccctcatctccaggagccggggaagctgat
actgagagtgacgacgatgacgatgatgacgactgtaaaaaatcttcaatggatgagggt
actgctggcagtgaggccatggccacagaagagatgtctaacctggtgaactatattcag
ccagtcaagtttgagtcctttgaaacttcaaaaaaaagaaatagaagttttgaaatgtct
tccttcgtggaaaccaaaggactcgagcaactgacaaagtctccagtggaatttgtagaa
tataacaaaatgcagctcagcaggatatatccaaaaggaacccgtgtggattcatccaac
tacatgcctcagctcttctggaatgctggttgccaaatggttgcacttaattttcaaact
gtggacctggctatgcaaataaatatggggatgtatgaatacaatgggaaaagtggctac
agattaaagccagagttcatgaggagacccgacaagcactttgatccattcaccgaaggc
atcgtagatgggatagtggccaacactttatctgtgaagattatttcaggtcagtttctt
tctgataagaaagttgggacctatgtggaagtggatatgtttggtttgcctgtggacaca
aggaggaaggcatttaagaccaaaacatcacaaggaaatgctgtaaatcctgtctgggaa
gaagagcccattgtgttcaaaaaggtggttcttccttctctggcctgtttgaggatagca
gtttatgaagaaggaggtaaatttatcggtcaccggatcttgcctgtacaggcaattcgg
ccaggctatcactacatctgtctgcggaatgagaggaaccagcctctgatgctcccagct
gtctttgtctacatagaggtgaaagactatgtcccagatacatatgcagatgtgattgaa
gctttgtcaaatccaatacgatatgtgaatctgatggagcagagagcaaagcaactggct
gctctgacactggaagatgaagaagaagtaaagaaagaggctgatcctggggaaacacca
tcagaagctccaagtgaaaccaggacaactccagcagaaaacggagtgaatcacactaca
tccctggcacccaaaccaccctcccaggctccccacagccaaccagctccaggttctgta
aaggcacctgccaaaacagaagatcttattcagagtgttttaacagaagtggaagcacag
actatcgaagagctaaagcaacagaaaccgtttgtgaaacttcaaaagaagcactacaaa
gaaatgaaagacctggtgaaaagacaccacaagaaaaccactgaccttatcaaagaacac
actacaaaatataatgaaattcagaatgactacttgagaaggagggcagctttggaaaag
acagccaaaaaggatagtaagaaaaaatcagaacccagcagtcctgaccatggttcatca
acaattgagcaagatcttgctgccctagatgctgaaatgacccaaaagttaatagacttg
aaggacaaacaacagcagcagctgcttaatcttcgacaagaacagtattacagtgagaaa
taccagaagcgagaacatattaaactgcttattcagaaattgacggatgttgccgaagaa
tgtcagaacaatcagctgaagaagctcaaagaaatctgtgagaaggagaagaaggaatta
aagaagaaaatggataaaaaaaggcaggagaagatcacagaagctaaatccaaagacaaa
agtcaaatggaagaggaaaagacagagatgatccggtcatacatccaggaggtggtacag
tacatcaagaggttagaagaggcacaaagtaaacggcaagaaaaacttgtagagaaacac
aaggagatccgtcagcagatcctggatgaaaagcccaagctgcagatggatctggagcaa
gagtaccaagacaagttcaaaagactgcccctggagatcttggagttcgtgcaggaagcc
atgaaagggaagatcagtgaagacagcaatcacagttctgcccctccctccctggcctca
gaccctggaaaactgaaccacaggcctccttccagtgaggagctagaaggggacaaccca
ggaaaagagtttgatactcctctgtga

DBGET integrated database retrieval system