KEGG   Felis catus (domestic cat): 101092925Help
Entry
101092925         CDS       T02385                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101092925 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101092925 (PLCG1)
   04015 Rap1 signaling pathway
    101092925 (PLCG1)
   04012 ErbB signaling pathway
    101092925 (PLCG1)
   04370 VEGF signaling pathway
    101092925 (PLCG1)
   04064 NF-kappa B signaling pathway
    101092925 (PLCG1)
   04066 HIF-1 signaling pathway
    101092925 (PLCG1)
   04020 Calcium signaling pathway
    101092925 (PLCG1)
   04070 Phosphatidylinositol signaling system
    101092925 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    101092925 (PLCG1)
   04660 T cell receptor signaling pathway
    101092925 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    101092925 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    101092925 (PLCG1)
   04670 Leukocyte transendothelial migration
    101092925 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    101092925 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    101092925 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101092925 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101092925 (PLCG1)
   05206 MicroRNAs in cancer
    101092925 (PLCG1)
   05205 Proteoglycans in cancer
    101092925 (PLCG1)
   05214 Glioma
    101092925 (PLCG1)
   05223 Non-small cell lung cancer
    101092925 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    101092925 (PLCG1)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101092925 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
A3
AA seq 1179 aa AA seqDB search
MEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRI
SAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSSDITYGQFAQLYRSLMYSAQKTMDLPF
LEASALRAVERPELCRVSLPEFQQFLLEYQGELWAIDQLQVQEFMLSFLRDPLREIEEPY
FFLDEFVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEA
YARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILS
IEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAY
EEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDE
EEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV
GDYTLSFWRNGKVQHCRIHSRQDAGAPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR
LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKI
KHCRVQQEGQTVVLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYG
ALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGD
YGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNN
RLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALE
LSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIY
PKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDE
AFDPFDKSSLRGLEPYAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVV
DNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKAGYRAVPL
KNNYSEDLELASLLIKIEVFPAKQENGDVSPFSSMSLRERGSDASGQLFHGRGREGSFEA
RYQQPFEDFRVSQEHLADHFDSRERRAPRRTRVNGDNRL
NT seq 3540 nt NT seq  +upstreamnt  +downstreamnt
atggagttccgcctgaagaccctgagcctgcaagctacatctgaggatgaagtgaacatg
tggatcaaggggttaacttggctgatggaagatacattgcaggcggccacacctctgcag
attgaaaggtggctgaggaagcagttctattcggtggatcggaatcgtgaggatcgtata
tcagccaaggacctgaagaacatgctgtcccaggtcaactaccgggtccccaacatgcgc
ttcctccgagagcgtctgacggacctggagcagcgcagcagtgacatcacctatgggcag
tttgctcagctgtaccgcagcctcatgtacagcgcccagaagacgatggacctccccttc
ttggaagccagtgccctgagggcggtggagcggccggagctctgtcgcgtgtcccttcct
gagttccagcagttcctcctcgagtaccagggggagctgtgggccatcgaccagcttcag
gtgcaagaatttatgctcagctttctccgagaccccttgcgagagattgaagagccgtac
ttcttcctggatgagtttgtcaccttcctgttctccaaagagaacagtgtgtggaactca
cagctggatgcagtgtgcccagaaaccatgaacaaccccctctcccactactggatctcc
tcctcccacaacacatacctgaccggggaccagttctccagcgagtcctccctggaagcc
tacgctcgctgcctgcggatgggctgtcgctgcattgagttggactgctgggatggccca
gatgggatgccagtcatttaccatggacacacccttaccaccaagatcaagttctcagac
gtcctgcacactatcaaggagcacgcctttgtggcctcagagtacccggtcatcctgtcc
attgaggaccattgcagcattgcccagcagaggaacatggcacagtacttcaagaaggtg
cttggggacacactccttaccaagcctgtggacatcgctgccgatggactcccctcaccc
aaccagctcaagaggaagatccttatcaagcacaagaagctggcagagggcagtgcctat
gaagaggtgcctacatcagtgatgtactccgagaacgatatcagcaactccatcaagaat
ggcatcctctacctggaggaccctgtgaaccacgagtggtatccccactacttcgtcctg
accagcagcaaaatctactactctgaggagacgagcagtgaccagggcaacgaggatgag
gaggagcccaaggaggccagtggcagcacagagctgcactccagtgagaaatggttccac
gggaagctcggggcaggacgggatgggcggcacatcgctgagcgcctgcttaccgagtac
tgcattgagaccggggcccctgatggctccttcctcgtgcgagagagcgagaccttcgtg
ggcgactataccctctctttctggcggaatgggaaagtccagcactgccggatccactct
cggcaggacgctggggcccccaagttcttcttgacagacaacctggtctttgactcgctc
tatgacctcatcacacactaccagcaggtgcccctacgctgcaacgaatttgagatgcgc
ctctcagagccagtcccgcagaccaatgcccacgagagcaaagagtggtaccatgccagc
ctgaccagagctcaggccgagcacatgctgatgcgcgtcccccgggatggggccttcctg
gtgaggaaacggaatgagcccaactcctacgccatctccttccgggctgagggcaagatc
aagcattgccgcgtccagcaggagggccagacggtggtcctgggcaactcagagttcgac
agcctcgtggacctcatcagctactacgagaagcacccactgtaccgcaagatgaagctg
cgctatcccatcaacgaggaggcgctggagaagatcggcacagctgagccagactacggg
gccctgtatgagggccgcaacccaggcttctatgtggaggcgaatcctatgccgactttc
aagtgtgcagtcaaagcactctttgactacaaggcccagagagaggatgagctgactttc
actaagagcgccatcatccagaacgtggagaagcaagaaggtggctggtggcggggggac
tatggtgggaagaagcagctgtggttcccgtcaaactacgtggaagagatggtcagcccc
gcagccctggagcctgagagggagcacttggacgagaacagccccttgggggatttgctc
cggggggtcttggatgtgccagcttgtcagattgccatccgtcccgagggcaagaacaac
cggctgttcgtcttctccatcagtatggcttccgtggcgcactggtccctggatgtcgct
gctgactcacaagaggagctgcaggactgggtgaagaagatccgagaagtggcccagacg
gcagacgccaggctcacggagggcaagatgatggagcggaggaagaagatcgccctggag
ctctccgagctggttgtctactgtcgacctgttccctttgatgaagagaagattggcaca
gaacgtgcctgctaccgggacatgtcgtccttcccggaaaccaaggctgagaaatacgtg
aacaaggccaaaggcaagaagtttctccagtacaaccggctgcagctctcccgcatctac
cccaagggccagcggctggactcttccaattacgaccccttgcccatgtggatctgtggc
agtcagctcgtggctctcaacttccagaccccagacaagcctatgcagatgaaccaggcc
ctcttcatggccggtggccactgtggctacgtgctgcagccgagcaccatgcgggatgag
gcctttgatccctttgacaagagcagcctccgaggcctggagccatatgccatctgcatc
gaggtgctgggggcccggcacctgccgaagaatggccgaggcatcgtgtgtccttttgtg
gagattgaggtggccggagcagagtatgacagcatcaaacagaagacagaatttgtggtg
gacaacggactgaaccctgtttggcccgccaagcccttccacttccagatcagtaaccca
gaattcgccttcctgcgctttgtggtgtatgaggaggacatgttcagtgaccagaacttc
ctggctcaggccaccttcccagtaaagggcttgaaggcaggatacagagccgtgcctttg
aagaacaactacagtgaggacctggagctggcctccctgctcatcaagatcgaggttttc
cctgccaagcaggagaacggtgacgtcagtcccttcagtagcatgtctctgcgcgagcgg
ggctccgatgcctcgggtcagctgttccatggccggggccgggaaggttcctttgaagcc
cgctaccagcagccgtttgaggactttcgtgtctcccaagagcatctggcagaccatttt
gacagtcgggaacggagggccccacgaaggactcgggtcaacggggacaaccgcctctag

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