KEGG   Felis catus (domestic cat): 101092961Help
Entry
101092961         CDS       T02385                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101092961 (PLCB3)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    101092961 (PLCB3)
   04310 Wnt signaling pathway
    101092961 (PLCB3)
   04020 Calcium signaling pathway
    101092961 (PLCB3)
   04070 Phosphatidylinositol signaling system
    101092961 (PLCB3)
   04022 cGMP - PKG signaling pathway
    101092961 (PLCB3)
 Cellular Processes
  Cell communication
   04540 Gap junction
    101092961 (PLCB3)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101092961 (PLCB3)
   04062 Chemokine signaling pathway
    101092961 (PLCB3)
  Endocrine system
   04911 Insulin secretion
    101092961 (PLCB3)
   04912 GnRH signaling pathway
    101092961 (PLCB3)
   04915 Estrogen signaling pathway
    101092961 (PLCB3)
   04921 Oxytocin signaling pathway
    101092961 (PLCB3)
   04918 Thyroid hormone synthesis
    101092961 (PLCB3)
   04919 Thyroid hormone signaling pathway
    101092961 (PLCB3)
   04916 Melanogenesis
    101092961 (PLCB3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101092961 (PLCB3)
   04270 Vascular smooth muscle contraction
    101092961 (PLCB3)
  Digestive system
   04970 Salivary secretion
    101092961 (PLCB3)
   04971 Gastric acid secretion
    101092961 (PLCB3)
   04972 Pancreatic secretion
    101092961 (PLCB3)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101092961 (PLCB3)
  Nervous system
   04724 Glutamatergic synapse
    101092961 (PLCB3)
   04725 Cholinergic synapse
    101092961 (PLCB3)
   04728 Dopaminergic synapse
    101092961 (PLCB3)
   04726 Serotonergic synapse
    101092961 (PLCB3)
   04720 Long-term potentiation
    101092961 (PLCB3)
   04730 Long-term depression
    101092961 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    101092961 (PLCB3)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101092961 (PLCB3)
  Environmental adaptation
   04713 Circadian entrainment
    101092961 (PLCB3)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    101092961 (PLCB3)
   05016 Huntington's disease
    101092961 (PLCB3)
  Infectious diseases
   05146 Amoebiasis
    101092961 (PLCB3)
   05142 Chagas disease (American trypanosomiasis)
    101092961 (PLCB3)
   05143 African trypanosomiasis
    101092961 (PLCB3)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101092961 (PLCB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
D1
AA seq 1191 aa AA seqDB search
MEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFL
NFMAVQDDTAKVWTEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKM
FSADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGK
PYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSR
YLGGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGC
RCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDS
AKQQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHQPSTGVP
NSSIRKRPLEQSSSALSESSATTEPSSPQLGSPSSDSCLGLSNGEELGLEKPSLEPRKSL
GEEGLQRGPDALGSADREDEEEDEEEEEQADPKKPTSDEGTASSEVNATEEMSTLVNYIE
PVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSN
YMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEV
IVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDE
EPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPAL
LIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQVGPETCQETPSQ
QPVTPNPTPSTLDISPRRPPGPATSPTSPSLGSPGQRDDLIASLLSEVAPAPLDELRGHK
ALVKLRSRQERELRELHKKHQRKAVALTRRLLDSLAQARAERRCRQRPGVLHRPPSPSPC
DNLSVTQRGSSCRGGEDEKAEEEEVKRYREFQKRQVQSLLELREAQADTEAERRLEHLRQ
AQQRLREIVLDAHATQFKRLKETNEREKKELQKILDRKRHNSISEAKTREKHKKEAELTE
INRRHITESVNSIRRLEEAQKQRHERLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARL
PQEACRSLLGETPEGLGDGHLVACASNGHAPGSGGHLSGADSESQEENTKL
NT seq 3576 nt NT seq  +upstreamnt  +downstreamnt
atggaggtggacaccctggacatcagttccatcagggacacgcggacgggccgttatgcc
cgcctgcccaaggaccccaagatccgagaggtgctgggctttggaggccctgacacccgg
ctggaggagaagttgatgacagtggtggccgggccagacccggtgaatacaacattcttg
aacttcatggccgtgcaggatgacacagccaaggtctggaccgaggagctgttcaagctg
gctatgaacatcctggctcagaacgcctcccggaacacctttctgagaaaagcatacacc
aagctgaagctgcaggtaaaccaggatggacggatcccagtgaagaacatcctgaagatg
ttctcagcagataagaagcgcgtcgagactgcgctggaatcctgtggcctcaatttcaac
cggagtgagtccatccggcccgacgagttctccttggaaatcttcgagcggttcctgaat
aagctgtgtctgcggccagacattgacaagatcctgctggagataggcgccaagggcaag
ccatacctgacgctggagcagctcatggacttcatcaaccagaagcaacgggacccgagg
ctcaacgaagtgctgtatccacccctgcggccctcccaggcccggctgctcattgagaag
tatgagcccaaccagcagttcctggaacgagaccagatgtccatggagggcttcagccgc
tacctggggggtgaggagaatggaatcctgcccttggaggccctggatctgagcgcagac
atgacccagccgctaagcgcctacttcatcaactcctcacacaacacctatctcacagcg
gggcagctggctgggacgtcgtcggtggagatgtaccggcaggcactgctctggggctgc
cgctgcgtggagctggacgtgtggaaagggcggcccccggaggaggagccctttatcacc
cacggcttcaccatgaccaccgaggtgccgctgcgagacgtgctcgaggccattgcggaa
accgccttcaagacctcgccctaccctgtcatcctctccttcgagaaccacgtggactcg
gcaaagcaacaggcgaagatggccgagtactgtcgttcgatctttggggacgcgctgctc
atcgacccactggacaagtacccgctggccccaggcgtcccgctgcccagcccccaggac
ctgatgggccgcatcctggtgaagaacaagaagcgacaccagcccagcactggtgtcccc
aacagctccattcgcaagcggccgctggagcagagcagctcggccctgagcgagagctct
gccaccaccgagccctcctcgcctcagctcgggtcccccagctctgacagctgcctgggc
ctgagcaatggggaagagctgggccttgagaagcccagcctggagcctcggaagtctctg
ggcgaggaggggctacagcggggccctgatgctcttggatctgccgaccgtgaggacgag
gaggaagacgaggaagaggaggaacaggcagatcccaaaaagccgacctcggatgagggc
actgccagcagtgaagtcaatgccactgaggagatgtcaaccctcgtcaactacatcgag
cctgtcaagttcaagtcctttgaggctgctcgaaagaggaacaaatgcttcgagatgtca
tccttcgtggaaaccaaggccatggagcaactgaccaagagccccatggagtttgtggaa
tacaataaacaacagctcagccgcatctaccccaagggcacccgcgtggactcctccaac
tacatgccccagctcttctggaacgtgggctgccagcttgtggccctcaactttcagacc
ctggatgtggcgatgcagctcaacgcgggtgtgtttgagtacaacggacgcagcggctac
ctgctcaagcccgagttcatgcggcggccggacaagtccttcgaccccttcaccgaagtc
atcgtggacggcatcgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctg
tccgacaggaaggtgggcatctacgtggaggtggacatgtttggcctccccgttgacaca
cggcgcaaataccgcactcggacgtctcaggggaactcattcaatcctgtgtgggatgag
gaaccctttgacttccccaaggtggtgctccccacgctggcttcgctccgcatcgcggcc
tttgaggaaggtggcaagtttgtggggcatcggattctgcccgtctctgccatccgttca
gggtaccactacatttgcctgcggaacgaggccaaccagccgctctgcctgccagccctg
ctcatatacaccgaagcctccgactatattcctgatgaccaccaggactacgcagaggcc
ctgatcaaccccatcaagcatgtcagcctgatggaccagagggccaagcagttggccgcc
ctcatcggggagagcgaggctcaggttggcccagaaacctgtcaggagactccatctcag
cagccggtgaccccaaaccccacacccagcacactggacatctccccgcgccggcccccg
ggccccgccacgtcccctaccagcccctccctcggcagcccagggcagcgcgacgacctc
atcgccagcctcctctcagaggtggccccggccccgctggacgagctccgaggccacaag
gctctggtgaaactccggagccgtcaagagcgagagcttcgggagctgcacaagaagcat
cagcggaaggcggttgccctcactcgccggttgctcgacagcttggcccaggcccgggct
gagcgcaggtgccggcagcggccgggtgtcctacaccgccctcccagcccgagtccctgt
gacaacctgagtgtcacccagaggggttcttcctgcagaggcggggaggacgagaaggcg
gaggaggaagaggtgaagcggtatcgagagttccagaagagacaggtgcagagtctgctg
gagctgcgggaggcccaggcggatacagaggccgagcggaggctggagcatctgcgacag
gctcagcagcggctcagggagatcgtcctggatgctcacgccacccagttcaagcggctg
aaggagacgaatgagagggagaagaaggaactgcagaagattctggacaggaagcgccac
aacagtatctcagaagccaagacaagggagaaacataagaaggaggcggaactgacagag
attaaccgtcggcacatcaccgagtccgtcaactccatccgtcggctggaggaggcccag
aagcagcggcacgaacgccttgtggccgggcagcagcaggtgctgcagcagctggccgaa
gaagagcccaagctgctggcccaactggcccaggagtgtcaggaacagcgggcaaggctg
ccccaggaggcctgccggagcctgctgggcgagacgccggaggggctgggggacgggcat
ctggtggcctgtgccagcaatggtcacgcacctgggagcggcgggcacctgtctggcgct
gactcagagagccaagaggagaatacgaagctctga

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