KEGG   Felis catus (domestic cat): 101094274Help
Entry
101094274         CDS       T02385                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
fca  Felis catus (domestic cat)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101094274 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101094274 (PIK3CD)
   04015 Rap1 signaling pathway
    101094274 (PIK3CD)
   04012 ErbB signaling pathway
    101094274 (PIK3CD)
   04370 VEGF signaling pathway
    101094274 (PIK3CD)
   04630 Jak-STAT signaling pathway
    101094274 (PIK3CD)
   04668 TNF signaling pathway
    101094274 (PIK3CD)
   04066 HIF-1 signaling pathway
    101094274 (PIK3CD)
   04068 FoxO signaling pathway
    101094274 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    101094274 (PIK3CD)
   04024 cAMP signaling pathway
    101094274 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    101094274 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    101094274 (PIK3CD)
   04152 AMPK signaling pathway
    101094274 (PIK3CD)
   04150 mTOR signaling pathway
    101094274 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    101094274 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    101094274 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    101094274 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    101094274 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    101094274 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    101094274 (PIK3CD)
   04660 T cell receptor signaling pathway
    101094274 (PIK3CD)
   04662 B cell receptor signaling pathway
    101094274 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    101094274 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    101094274 (PIK3CD)
   04670 Leukocyte transendothelial migration
    101094274 (PIK3CD)
   04062 Chemokine signaling pathway
    101094274 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    101094274 (PIK3CD)
   04915 Estrogen signaling pathway
    101094274 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    101094274 (PIK3CD)
   04917 Prolactin signaling pathway
    101094274 (PIK3CD)
   04921 Oxytocin signaling pathway
    101094274 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    101094274 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101094274 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    101094274 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101094274 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    101094274 (PIK3CD)
   04722 Neurotrophin signaling pathway
    101094274 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101094274 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    101094274 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101094274 (PIK3CD)
   05205 Proteoglycans in cancer
    101094274 (PIK3CD)
   05203 Viral carcinogenesis
    101094274 (PIK3CD)
   05210 Colorectal cancer
    101094274 (PIK3CD)
   05212 Pancreatic cancer
    101094274 (PIK3CD)
   05214 Glioma
    101094274 (PIK3CD)
   05221 Acute myeloid leukemia
    101094274 (PIK3CD)
   05220 Chronic myeloid leukemia
    101094274 (PIK3CD)
   05218 Melanoma
    101094274 (PIK3CD)
   05211 Renal cell carcinoma
    101094274 (PIK3CD)
   05215 Prostate cancer
    101094274 (PIK3CD)
   05213 Endometrial cancer
    101094274 (PIK3CD)
   05222 Small cell lung cancer
    101094274 (PIK3CD)
   05223 Non-small cell lung cancer
    101094274 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101094274 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    101094274 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    101094274 (PIK3CD)
   05166 HTLV-I infection
    101094274 (PIK3CD)
   05162 Measles
    101094274 (PIK3CD)
   05164 Influenza A
    101094274 (PIK3CD)
   05161 Hepatitis B
    101094274 (PIK3CD)
   05160 Hepatitis C
    101094274 (PIK3CD)
   05169 Epstein-Barr virus infection
    101094274 (PIK3CD)
   05146 Amoebiasis
    101094274 (PIK3CD)
   05145 Toxoplasmosis
    101094274 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    101094274 (PIK3CD)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     101094274 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
C1
AA seq 1043 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
NT seq 3132 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggttgactgccccatggaattctggaccaaggaggagaatcagagtgtg
gcagttgacttcctgctgcccacgggggtctatctgaacttccctgtgtcccggaatgcc
aacctcagcaccatcaagaaggtgttgtggcaccgcgcccagtatgagccactcttccac
atgctcagcgaccctgaggcctacgtgttcacctgcgtcaaccagaccgcggagcagcag
gagctggaggacgagcagcggcgactgtgtgacatccagcccttcctgccggtgctgcgc
ctggtggcccgagagggtgacagggtgaagaagcttgtcaactcacagatcagcctcctc
atcggcaaaggcctccacgagttcgactccttgcgggaccccgaggtgaatgactttcgc
accaagatgcgccagttctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggctgcagtacagcttccccctgcagctggagccctcggcccggagctggggggcc
ggcaccctgcgggtccccaaccgggccctcctcgtcaacgtcaagtttgagggcagcgag
gagagcttcaccttccaggtgtccagcaaggatgtgcccctggcactgatggcctgtgcc
ctccggaagaaggccacggtgttccggcagccgctgctggagcggcctgaggactacacc
ctgcaggtgaacgggaagcacgagtacctctacggcagctaccccctctgccagttccag
tacatctgcagctgcttgcacagcgggctgaccccccacctgaccatggtgcactcttct
tccatcctcgccatgcgggatgagcagagcaaccctgccccccaagtccaaaaaccacgc
accaaaccgccccccattcccatgaagaagccttcttccttgtccctgtggtccctggag
cagcctttctgcgtggagctgatccagggtagcaaagtgaatgcggatgagcggatgaag
ctggtggtgcaggccgggctcttccatggcaacgagacgctgtgcaagacggtgtccagc
tcggaggtgagcgtgtgctcagagcccgtgtggaagcagcggctagagtttgacatcaac
gtctgcgacctgcctcgcatggctcgtctctgctttgcactttacgccgtgatcgagaag
gccaagaaggctcggtccaccaagaagaagtccaagaaggcggactgccccatcgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagaccggtgaatgctgcctgtac
atgtggccgtccgcaccagacgagaagggggagctgctgaaccccgcgggaacagtgcgg
agtaaccccaacacggagagcgctgctgccctagtcatctgcctccctgaggtgtccccc
taccctgtgtactacccggccctggacaagattctggagctggggcggcacggggagcac
gggcgcttcagcgaggaggagctgcagctgcgggaaatcctggagcggcgggggtccggg
gagctgtatgagcacgagaaagacctggtgtggaagatgcggcacgaggtccaggagcgc
ttcccggaggcgctggcccgcctgctgctggtcaccaagtggaacaagcacgaggatgtg
gcccagatgctctacctgctgtgctcctggccggacctgcccgtcctgagcgccctggag
ctgctggacttcagcttccccgaccgccacgtgggctccttcgccatcaagtctctgcgg
aaactgacggacgacgagcttttccagtacctgctgcagctggtgcaggtcctcaagtac
gagtcctacctggactgcgagctgaccaagttcctgctggaccgggccctgtccaaccgc
aagatcggccacttccttttctggcacctccgctccgagatgcacgtgccctccgtggcg
ctgcgcttcggcctcatcatggaagcctactgcaggggcagcacccaccacatgaaggtg
ctgatgaggcagggcgaggcgctgagcaaactgaaggccctgaacgactttgtcaaggtg
agctcccagaagaccacccggccccagaccaaagagctgatgcacctgtgcatgcgccag
gagacctacctggaggccctctccaacctgcagtccccgctggaccccagcaccctgctg
gccgaagtctgcgtggaacagtgcaccttcatggactccaagatgaagcccctgtgggtc
atgtacagcaacgaggaggcgggcagtgacagcagtgtgggcatcatctttaagaacggg
gacgacctccgccaggacatgctgactctgcagatgatccagctcatggacgttctgtgg
aagcaggagggattggacctgaggatgaccccctatggctgcctctccacgggggaccgc
acaggcctcatcgaggtggtgcttcactcagacaccatcgccaacatccagctgaacaaa
agcaacatggcagccacggctgccttcaacaaggatgccctgctcaactggctcaagtcc
aagaaccctggggaagccttggatcgagccattgaggagtttaccctctcctgcgcgggt
tactgtgtggccacttacgtgttgggcatcggtgatcgtcacagtgacaacatcatgatc
cgcgagaatgggcagctgttccacattgattttggccactttctggggaatttcaagacc
aagtttggaatcaaccgtgagcgcgtcccattcatcctcacgtacgactttgtgcacgtg
atccagcaggggaaaacgaataacagtgagaaatttgaaaggttccgtggctactgtgag
cgagcctataccatcctgcggcgccacgggcctctgttccttcacctcttcgccctgatg
cgggccgccggcctgcctgagctcagctgctccaaagacatccagtatctcaaggactct
ctggccttgggaaagacagaggaggaggctctaaagcacttccgagtgaagttcaacgaa
gccctccgggagagctggaagaccaaagtgaactggctggcccacaacgtgtccaaagac
aacaggcagtag

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