KEGG T02385: 101100222

Felis catus (domestic cat): 101100222

Entry

101100222 CDS T02385

Gene name

ITGA8

Definition

integrin, alpha 8

Orthology

K06584

integrin alpha 8

Organism

fca Felis catus (domestic cat)

Pathway

fca04151	PI3K-Akt signaling pathway
fca04510	Focal adhesion
fca04512	ECM-receptor interaction
fca04514	Cell adhesion molecules (CAMs)
fca04810	Regulation of actin cytoskeleton
fca05410	Hypertrophic cardiomyopathy (HCM)
fca05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
fca05414	Dilated cardiomyopathy

Class

Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:fca04151]
Environmental Information Processing; Signaling molecules and interaction; ECM-receptor interaction [PATH:fca04512]
Environmental Information Processing; Signaling molecules and interaction; Cell adhesion molecules (CAMs) [PATH:fca04514]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:fca04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:fca04510]
Human Diseases; Cardiovascular diseases; Hypertrophic cardiomyopathy (HCM) [PATH:fca05410]
Human Diseases; Cardiovascular diseases; Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:fca05412]
Human Diseases; Cardiovascular diseases; Dilated cardiomyopathy (DCM) [PATH:fca05414]

SSDB

Motif

Pfam:

Integrin_alpha2 FG-GAP VCBS Integrin_alpha

Other DBs

NCBI-GI:

410963318

NCBI-GeneID:

101100222

Position

AA seq 1028 aa
MSARARRGPRDGRAQWLAPLWCLSAALGVLRTPASQAFNLDVDKLTVYSGPEGSYFGYAV
DFHIPAARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCKQIPFDNTNNRKIRV
NGTKEPIEFKSNQWFGATVKAHRGEVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAY
AEYSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASIADIIANYS
FKDILRKLAREKQTDVAPASYDDSYLGYSVAAGEFTGDSEQELVAGVPRGAQNFGYVSII
NSTDMTFIQNFTGEQMASYFGYTVTVSDVNNDGMDDVLIGAPLFMEREFETSPREVGQVY
LYLQVSALVFRDPQILAGTEVFGRFGSAVAHLGDLNQDGYNDIAIGAPFAGKDQRGKVLI
YNGNKDGLHTKASQILQGLWASQTIPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVY
RARPVVTVDAQLLLHPMIINLENKTCQIPESVSPVACFSLKVCASVAGQSISNTIGLTAE
VYLDTLKQKGAVKRTLFLDNNQSHFIFPLTIKRQKSLQCQDFVVYLRDETEFRDKLSPIN
ISLNYSLDESTFKEGLDVKPILNYYKENTVTEQAHILVDCGEDNMCIPDLKLSARPDKYQ
VIIGDENHLMLVINARNEGEGAYEAELFVMIPEEADYVGIERSNKGLRPLSCEYKMENTS
RMVVCDLGNPMVAGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINI
TAVAQVEIRGVSHPPQIVLPVPNWEPEEELHKEEGVGPVVEHIYELHNIGPSTISDTLLE
VGWPFSARDEFLLYIFHIQTLGPLQCQTNPDINPLDIKPATPPEDTPELSAFLRNSTIPH
LVRKRDVRVPEPHRQSPAKILNCTNIECLQISCVVGRLEGGESAVLKVRSRLWAKTFLQI
KTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQDDMNDREQL
TDEKTIDT

NT seq 3087 nt +upstreamnt +downstreamnt
atgtctgcccgggcccgccgcggtccccgggacggccgggcgcagtggctcgcgcccctc
tggtgcctctcggccgcgctgggcgtgctgcggacccccgcctcgcaggcgttcaacttg
gacgtggacaagctcaccgtgtacagcggccccgagggcagctacttcggctacgcggtg
gacttccacatacctgccgctcgcacagcgagtgtcttggtgggggcgcccaaagccaac
accagccagccagacatcgtggaagggggagcggtctattactgtccctggcccgccgag
gggtctgcacagtgcaagcagatcccgtttgacaacaccaacaacagaaagatcagagtt
aatggaaccaaggaacctatagaatttaaatcgaatcagtggtttggggcaacagtgaaa
gctcaccgaggcgaagttgtggcctgcgctcccttataccactggagaactcttaagcca
acaccggagaaggacccggtcggcacctgctacgtagcaattcagaatttcagcgcgtat
gcggagtattcgccttgtcggaacagtaatgctgatcccgaaggccagggttactgccaa
gcaggatttagtctggatttttacaagaatggagacctcatagtgggaggacccgggagt
ttttattggcaaggtcaggtgatcactgccagtattgcagatatcattgcgaattactcg
ttcaaggatatcctaaggaaattggctcgagagaaacagacagacgtggctccagcttcc
tatgatgacagttaccttggatattcagttgctgctggggaattcactggagactctgag
caagagctggttgccggagttccaagaggagcacagaattttggatatgtttcaatcatt
aactctacagatatgacttttattcagaatttcactggtgaacagatggcatcttatttt
ggatatacagtcacagtgtcagatgttaacaatgatggaatggatgatgtattgattggg
gcccctctcttcatggaacgtgaatttgagaccagccctagggaagtagggcaagtttat
ctgtatttgcaagtgagtgctcttgtcttcagagacccacagatcctcgcgggcaccgag
gttttcgggagattcggtagtgctgtggcacacttaggagacctgaaccaagatggatac
aatgacattgccatcggggcaccctttgcaggcaaggaccaaagaggcaaagtgctcatt
tacaacgggaacaaggatggcttacacaccaaggcgtcccagattctgcaaggattgtgg
gcctcccagaccatcccttctggattcggctttactctcagaggagattcggacatagac
aagaatgattacccagatttgattgtaggtgccttcggaacaggaaaagtagctgtttac
agagcaaggccagtcgtgactgtggatgcccagcttttgctgcacccgatgattatcaat
ctggaaaataaaacatgccagattccggagtctgtgtcacctgtggcctgcttttcttta
aaagtatgtgcttcagtagcgggccagagcatttcaaatacaataggcctgaccgccgag
gtatacttggatactctgaaacaaaaaggagccgtcaaacgcacgcttttccttgacaac
aatcagtcacatttcattttccctctcaccatcaagcggcagaaatccctccaatgccag
gactttgtcgtttacctccgagatgaaaccgaattccgagataaattatctccaatcaac
attagtttgaattacagtttggatgaatccacctttaaagaaggcctggatgtgaaacca
atattgaattactacaaggaaaacactgtcaccgagcaggctcacatcctggtggactgt
ggagaagacaacatgtgcattcctgacctgaagctgtcagctagaccagataagtatcag
gtcatcattggagatgaaaatcatcttatgctcgtaatcaatgcaagaaatgaaggagaa
ggtgcctacgaagctgaactcttcgtgatgataccagaagaggcagattatgttgggatt
gaacgcagcaacaaggggctacgtccactgagctgtgagtacaagatggaaaatacaagc
cggatggtggtgtgtgaccttggcaaccctatggtggctggaacaaattactctctgggc
ctccgatttgcagttccacgtcttgagaaaacaaacatgagcattaacttcgatctccaa
atcagaagttccaacaaggacaacccagacagcaattttgtgagcctgcaaatcaacatc
actgctgtagctcaagtagaaataagaggagtgtcgcaccctccgcagatcgttctgccc
gttcctaactgggaaccagaagaggagctccacaaagaggagggagttggaccagtggtg
gaacatatttatgagctgcacaatattggaccgagtaccatcagtgacactctcctggag
gtgggctggccattctctgcccgggatgaatttctcctctacatttttcatattcaaact
ctcggacctctgcagtgtcaaacaaatcctgacatcaacccactagatataaagcccgcc
acccccccagaggacacccccgagctgagcgcctttctacggaactcgaccatccctcat
cttgtcaggaagagagacgtgcgtgtgccagagccccatagacagagccccgcaaaaatc
ctcaattgtacaaatatcgagtgcttacaaatctcctgcgtggtggggcgactagaagga
ggagaaagcgccgtcctaaaagtcagatcacggttatgggccaagaccttcctccagatt
aagacatcagttatctgggcaaccccaaatgtttccttctcaatcccattatgggtaata
atactagcaatacttcttggattattggttctggccatcttaaccttagctttatggaag
tgcggattctttgacagagcaagaccaccccaggatgacatgaatgacagggaacaactc
acagatgagaaaaccattgatacatga

All links

Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (19)   

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