KEGG   Felis catus (domestic cat): 494146Help
Entry
494146            CDS       T02385                                 

Gene name
UGT1A
Definition
UDP-glucuronosyltransferase 1A (EC:2.4.1.17)
Orthology
K00699  
glucuronosyltransferase [EC:2.4.1.17]
Organism
fca  Felis catus (domestic cat)
Pathway
Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Starch and sucrose metabolism
Retinol metabolism
Porphyrin and chlorophyll metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Chemical carcinogenesis
Module
Glucuronate pathway (uronate pathway)
Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    494146 (UGT1A)
   00053 Ascorbate and aldarate metabolism
    494146 (UGT1A)
   00500 Starch and sucrose metabolism
    494146 (UGT1A)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    494146 (UGT1A)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    494146 (UGT1A)
   00860 Porphyrin and chlorophyll metabolism
    494146 (UGT1A)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    494146 (UGT1A)
   00982 Drug metabolism - cytochrome P450
    494146 (UGT1A)
   00983 Drug metabolism - other enzymes
    494146 (UGT1A)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    494146 (UGT1A)
Enzymes [BR:fca01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     494146 (UGT1A)
Glycosyltransferases [BR:fca01003]
 Others
  Hydrophobic molecule
   494146 (UGT1A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
AA seq 533 aa AA seqDB search
MAAGFLVPLPVLTGLLLFLCVGPRAEGGKVLVLPTDGSHWLSMKKALQELHARGHEIVVV
SPEVNLHIKKEDFFTLRTYAISYTQEEFNDFFLGHSYLVFEKGHFLKMFLKIMENLKTAS
FIFQRSCKELMHNKELIGHLNSSSFDVVLTDPVYPCGAVLAKYLSLPAVFFLRSVPCDLD
FEGTQCPNPSSYIPRLLTMNSDHMTFLQRVKNMLYPLSLKYICHIAFTPYASLASELLQR
EVSVVDVFSSASMWLFRGDFVLDYPRPVMPNMVFIGGINCANRKPLSQEFEAYVNASGEH
GIVVFSLGSMVSAIPKEKAMEIADALGKIPQTVLWRYTGTPPPNLAKNTILVKWLPQNDL
LGHPKARAFITHSGSHGIYEGICNGVPMVMLPLFGDQMDNAKRMETRGAGLTLNVLEMTS
EDLANGLKAVINDKSYKENIMRLSSLHKDRPIEPLDLAVFWVEFVMRHKGAPHLRPAAHD
LTWYQYHSVDVIGFLLAIVLGIVFITYKCCAFGCRKCFGRKGRVKKSHKSKTH
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atggctgcaggattcctggttcccctgccggtgctcacggggctgttgctgttcctgtgt
gtcgggccccgggctgaaggtgggaaggtgctggtcttgcccacggatggcagccactgg
ctcagcatgaagaaggccctgcaggagctccatgccagaggccacgaaatagtggtcgtt
tcgccagaggtgaatctgcatatcaaaaaagaggactttttcaccctgaggacctacgcc
atttcgtacacccaggaggaatttaatgacttctttctgggccactcttatctggttttt
gaaaaaggacattttctaaagatgtttttgaaaatcatggaaaatttgaaaactgcttct
ttcatttttcaaaggtcttgcaaggagctgatgcacaacaaggagctgatcgggcacctg
aactctagttcctttgatgtggttttaacagatcctgtttacccctgtggggcagtcctg
gctaagtacctgtcactgcctgccgtgttttttttgcgctctgttccatgcgacttagat
tttgagggcacgcagtgcccaaacccttcctcatatattcctaggctattaacaatgaat
tcagaccacatgacgttcctgcaaagggtcaagaacatgctctaccctctgtccctgaag
tacatttgccacattgctttcactccttacgcaagcctcgcctctgagctcctgcagaga
gaggtgtcggtggtggatgttttcagctctgcatccatgtggctgttcagaggagatttt
gtactggactaccccaggccagtgatgcccaacatggtcttcatcgggggcataaactgt
gccaacaggaagccattatcacaggaatttgaagcctatgttaatgcttctggagaacat
ggaattgtggttttctctttgggctccatggtctcagcgattcccaaggagaaagctatg
gaaattgctgatgctttgggcaaaatacctcagacagtcctgtggcggtatactggcact
ccaccaccaaatcttgcgaagaacacaatacttgtcaagtggcttccccaaaatgatctg
cttggtcacccgaaggctcgtgccttcatcacacattctggctcccatggcatatacgag
gggatatgcaatggcgttcccatggtgatgctgcccttatttggtgatcagatggacaac
gcgaagcgcatggagacccggggggctggattgaccttgaacgtcctggaaatgacttct
gaagatttagcaaatggcctaaaagctgtcatcaatgacaaaagctacaaggagaacatc
atgcgcctgtccagcctgcacaaggaccgccccatcgagcccctggacctggctgtgttc
tgggtagagttcgtgatgaggcacaagggggccccgcacctgcgccctgcagcccacgat
ctcacctggtaccaataccactctgtggacgtgatcggcttcctcctggccattgtgctg
ggcattgtcttcatcacgtacaaatgctgcgccttcggctgccggaagtgctttgggaga
aaaggacgagttaagaaatctcacaagtctaagacacactga

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