KEGG T02591: FP2

Faecalibacterium prausnitzii L2-6: FP2_27030

Entry

FP2_27030         CDS       T02591

Name

(GenBank) Methionine synthase I (cobalamin-dependent), methyltransferase domain

K24042

methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]

Organism

fpr Faecalibacterium prausnitzii L2-6

Pathway

fpr00270

Cysteine and methionine metabolism

fpr00450

Selenocompound metabolism

fpr00670

One carbon pool by folate

fpr01100

Metabolic pathways

fpr01110

Biosynthesis of secondary metabolites

fpr01120

Microbial metabolism in diverse environments

fpr01230

Biosynthesis of amino acids

Brite

KEGG Orthology (KO) [BR:fpr00001]
09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    FP2_27030
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    FP2_27030
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    FP2_27030
Enzymes [BR:fpr01000]
1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     FP2_27030
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     FP2_27030

SSDB

Motif

Pfam:

S-methyl_trans MTHFR

Other DBs

NCBI-ProteinID:

CBL00006

UniProt:

D4K157

Position

2741610..2743403

AA seq 597 aa
MTDIREYLAHKPLLFDGGMGTYYKAAPGADCEMANLTDPEGVKKVHAEYLAAGAQAIKTN
TFGLPRMAAAQTPGWEELAEAGWKLACDAAAEKDAAVFADLGPAPDTEAAPASSAYGLVA
QQFAALGAKNFLFETLSSDVGIVEAVKALRVAVPDAFVMVSFAVLPDGYTREGLLFRDLL
RRMEQSGVVDAVGLNCVSAPGAMKKLVQGLGETLLPLSVMPNAGYPVVTRARVLYQGKPA
YFAREMGQIAAAGVRILGGCCGTTPAHIAALRAELDALPQRTEAAPAAKLSTGTAPAVEK
DDAFLRKLNAGEKVIAIELDSPRVADLSGYLDGARRLQAAGADLLTIADCPIAQARMDSS
LVACRVHRELGMCALPHMTCRDRNLNATKALLLGLYAEGVREVLAITGDPIPTAERDEVK
NVYQFNSRKLAQYIVSLAGEGREMPSAMTVLGALNLNARNFDVELRRAVEKLENGMSGFL
TQPVLSAQAVENLRKARQTLGERAKILAGIMPVVSQRNAIFMENEINGIHVEEDIIQRFA
GLDREQGEALGLEVSMQMAREALPYADGFYLMTPFNRVALMERLIARLKTELLDAED

NT seq 1794 nt +upstreamnt +downstreamnt
atgacggacatccgagagtatcttgcccacaagccgcttttgtttgacggcggcatgggt
acctattataaagcggcaccgggcgcggactgcgaaatggccaacctcaccgaccccgag
ggcgtgaagaaggtccatgcggaatatctggccgcaggcgcacaggccatcaagaccaac
accttcggtctgccccggatggcggctgcccagacgccgggctgggaagagctggccgag
gcgggctggaagctggcctgtgacgctgccgctgagaaggatgccgccgtctttgctgac
ctcggcccggccccggacaccgaggctgccccagccagcagcgcttacggccttgtggcg
cagcagttcgccgcactgggggcaaagaactttctgttcgagacgctcagctccgatgtg
ggcattgtggaggcggtaaaggcactgcgtgtggccgtgccggacgcctttgtcatggtg
tccttcgcggtgctgccggacggctacacccgcgagggcctgctgttccgcgacctgctg
cgccggatggagcagagcggcgtggtggacgccgtgggcctgaactgcgtctcggccccc
ggcgcgatgaagaaactggtgcagggccttggcgagacgctgctgcctctgtcggtgatg
cctaatgcgggctatccggtggtcacccgggcgcgggtgctgtatcagggcaagcctgcg
tattttgcccgggagatggggcagatcgccgctgcgggcgtccgtattttgggcggctgc
tgcggcacgacgcccgcccacatcgcggccctgcgtgcagagctggatgccctgccccag
cggaccgaggccgctccggcagcgaagctttccaccgggacggcaccggcggtggaaaaa
gatgatgccttcctgcggaaactgaacgcaggtgagaaggtcatcgccattgaactggat
tcgccccgggtggccgacctgagcggctatctggacggcgcacggcggctgcaggccgca
ggcgctgacctgctgaccatcgccgactgccccatcgcacaggcccggatggattcctcc
ctcgtggcctgccgggtacaccgggaactgggaatgtgtgctctgccccacatgacctgc
cgcgaccgaaacctcaacgccaccaaggcccttctgctgggcctttacgccgagggcgtg
cgggaggtgctggccatcaccggcgaccccatccccaccgcagagcgggacgaggtgaag
aatgtctaccagttcaactcccgcaagctggcccagtacatcgtctcgctggccggggag
ggccgggagatgccctcggccatgaccgtccttggtgcgctgaatctcaacgcccggaac
tttgacgtggagctgcgccgggctgtggaaaagctggaaaacgggatgtcgggcttcctg
acccagccggtgctgtcggcgcaggcggtggaaaatctccgcaaggcccgtcagacactg
ggcgaacgtgctaaaatcctggccggcatcatgcccgtggtcagccagcggaacgccatc
ttcatggagaacgagatcaacggcatccatgtggaggaggacatcatccagcgctttgcg
ggcctcgaccgggagcagggcgaggcactgggccttgaggtgtcgatgcagatggcccgg
gaggctctgccctacgccgacggcttctatctcatgacccccttcaaccgtgtggccctg
atggagcggctcattgcccggctgaaaacggagcttctggacgcggaagactga

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