KEGG   Gallus gallus (chicken): 424826Help
Entry
424826            CDS       T01006                                 

Gene name
PIK3CB
Definition
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
gga  Gallus gallus (chicken)
Pathway
gga00562  Inositol phosphate metabolism
gga04012  ErbB signaling pathway
gga04068  FoxO signaling pathway
gga04070  Phosphatidylinositol signaling system
gga04140  Autophagy - animal
gga04150  mTOR signaling pathway
gga04210  Apoptosis
gga04218  Cellular senescence
gga04370  VEGF signaling pathway
gga04510  Focal adhesion
gga04620  Toll-like receptor signaling pathway
gga04625  C-type lectin receptor signaling pathway
gga04810  Regulation of actin cytoskeleton
gga04910  Insulin signaling pathway
gga04914  Progesterone-mediated oocyte maturation
gga04933  AGE-RAGE signaling pathway in diabetic complications
gga05164  Influenza A
Module
gga_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:gga00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    424826 (PIK3CB)
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    424826 (PIK3CB)
   04370 VEGF signaling pathway
    424826 (PIK3CB)
   04068 FoxO signaling pathway
    424826 (PIK3CB)
   04070 Phosphatidylinositol signaling system
    424826 (PIK3CB)
   04150 mTOR signaling pathway
    424826 (PIK3CB)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    424826 (PIK3CB)
  Cell growth and death
   04210 Apoptosis
    424826 (PIK3CB)
   04218 Cellular senescence
    424826 (PIK3CB)
  Cellular community - eukaryotes
   04510 Focal adhesion
    424826 (PIK3CB)
  Cell motility
   04810 Regulation of actin cytoskeleton
    424826 (PIK3CB)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    424826 (PIK3CB)
   04625 C-type lectin receptor signaling pathway
    424826 (PIK3CB)
  Endocrine system
   04910 Insulin signaling pathway
    424826 (PIK3CB)
   04914 Progesterone-mediated oocyte maturation
    424826 (PIK3CB)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    424826 (PIK3CB)
  Infectious diseases
   05164 Influenza A
    424826 (PIK3CB)
Enzymes [BR:gga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     424826 (PIK3CB)
Membrane trafficking [BR:gga04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    424826 (PIK3CB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_p85B PI3K_rbd PI3K_C2 DUF4135
Motif
Other DBs
NCBI-GeneID: 424826
NCBI-ProteinID: NP_001026482
CGNC: 4100
Ensembl: ENSGALG00000005505
UniProt: Q5F4A2
Position
9
AA seq 1066 aa AA seqDB search
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRATTSVWDICSPFKIVLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSTEISGRSDHAWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
NT seq 3201 nt NT seq  +upstreamnt  +downstreamnt
atgcctcctgccgtgacagacagccttgacatctgggcagtggattcacagatcggtgct
gatggctcaatatccgtggacttcctattgcccactggaatctacatcaacttggatgtc
cctcgagatgccactatatctcatattaagcagctgttatggaagcaggcacacacctat
ccactcttccatctcctcatggagattgactcttacatgttctcatgtgtgaatcagacg
gccgtacatgaagaattagaagatgaaacacggagactttgtgacgtcagaccctttctt
cctgtccttaaactagtgacaaggaattgtgatccaggagaaaagttggactccaaaata
ggtgttcttataggcaaaggtctccatgagtttgatgccttacaagatcctgaagtgaat
gactttcgagctaaaatgcggagaatcagtgaggagaagattcagtcgcttgtgggtctt
tcctggatggactggttaaagcacacttacccaccagaacaggaacccgttgtcccagag
aacttccaagataagctttatagtggaaatcttgtagtggctattcattttgataactgc
caggatgtatttagttttcaagtgtctcctaacatgaatcccatcaagttgaatgaactg
gcaatccgaaaacgtttgactatccatggaaaagaagatgaggaaattgatcctgctgac
tatgtgctgcaagttagtgggaggctagaatatgtttttggtgatcatccgttaattcag
tttcagtatatacacaactgtgtgatgaacaggactctccctcagctgactctagttgag
tgttgcaccataaagaaaatgtgtgagcaggaaatgatcgccatagaagttgccataaac
cgaaaatcatccaaccttcctcttcctctgccaccaaaaaaaacaagagcaacgactagt
gtatgggacatttgcagccctttcaagattgttctattgaagggtaataagctaaataca
gaagaaaatgccaaagttcatgttagggctggtattttccacggtacggagctcctttgt
aaaactattgtaagcacagaaatatctgggagaagtgaccatgcttggaatgaagtactg
gagtttgaaataaatgtctgtgatctaccaagaatggcaagactctgctttgcagtttat
gctgtgatggataagatgaaaactaaaaagtcaactaagtcaatgaatccctccaagtac
caaaccattagaaaagcaggaaaagtgcactaccctgtagcctgggtaaatactatggta
tttgattacaaaggacagctgaagaatggagaattcgtactgcacagctggtcatcattt
ccagatgagcttgaagaaatgttaaacccaatgggaactgtccagactaacccttacact
gaaaatgcaacagctttgcacattagatttcaagaatattcaaaacagcctattaattac
cctccctttgataagatacttgaaaaggcagctgagattgcaagaagcagtgacaacgct
gccatggcgggtcgaggtggtaaaaaattttatattgtgctaaaagaaataatggaaaga
gatcctttgtctcagctctgtgaaaatgaaatggatctcatctggactttgcgatatgac
tgtcgtgaaaattttccacaatcgttgccaaagctgctgctctccttaaaatggaacaaa
cttgaagatgttgctcagcttcaagctctccttcagatatggcccaagctgctgcctaga
gaagctttagaattgttggatttcaattaccccgaccagtatgtgagagaatatgcagtg
ggttgtttaaagcaaatgagtgatgaagagctttctcagtatcttcttcaacttgtgcaa
gtcctgaaatacgaaccttttcttgactgtgctctctccagatttctactagagagggca
cttgctaatagaagaataggacagatgttgttctggcatctgaggtcagaggttcacata
cctgctgtttcagtacagtttggtttgatacttgaagcttactgccgaggaagcgttgct
cacatgaaagtgcttgccaaacaggtggaagctcttaataaaatgaagactttaaacagc
ctaattaagctgaatgccatgaaacaaagcaaagcaaaaggaaaagatgcaatgcacaca
tgtttgaaacaaaatgcttacagagaagcactctctgacctccagtctcctctgaatcct
tctgttatactttcagaactgcatgttgagaagtgtaagtacatggattctaaaatgaaa
cctctatggatagtatacaacaacaagatgtttggaggagatcttgtagggatcatcttt
aaaaatggtgatgatctccgacaggacatgttgacactccagattttacgtttgatggac
gtactttggaaagaagctggcctggatctccggatattgccatacggctgtttagcaact
ggagatcattctggccttattgaggctgtttccagttcagaaaccattgctgacattcag
ctaaatagtagcaatgttgccgccgctgctgccttcaacaaagatgctctcttaaactgg
ctgaaggaatacaatttaggagatgacttggaccgagccattgaagaattcactctgtct
tgtgctggctactgtgtagctacttacgtgctggggattggcgacagacacagtgacaat
attatggtccgaaaaaatggtcagctctttcatatagactttgggcatattcttggaaac
ttcaagtccaagtttggaattaaaagggaaagggtacctttcatacttacctatgatttc
attcatgttattcaacaaggaaaaacagggaacaccgaaaaatttggtcggttccgccag
tattgtgaagaagcatacctgatcctgagaaaacatggaaacctatttattacacttttt
gcactgatgttaactgcagggcttccagagctaacctctgtcaaggacatccagtatctc
aaggattctcttgccttggggaagagtgaggaagaagcactaaaacaatttaagcaaaag
tttgatgaagcactccgggaaagctggactactaaagtgaactggatggctcacactgtt
cgcaaggattacagatcctag

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